在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ELF5 Antibody

  • 中文名稱:
    ELF5兔多克隆抗體
  • 貨號:
    CSB-PA002318
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HuvEc cells using Elf-5 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ELF5
  • 別名:
    E74 like factor 5 (ets domain transcription factor) antibody; E74 like factor 5 antibody; E74-like factor 5 antibody; ELF 5 antibody; ELF5 antibody; ELF5_HUMAN antibody; Epithelium restricted ESE 1 related Ets factor antibody; Epithelium restricted ESE1 related Ets factor antibody; Epithelium specific Ets transcription factor 2 antibody; Epithelium-restricted ESE-1-related Ets factor antibody; Epithelium-specific Ets transcription factor 2 antibody; ESE 2 antibody; ESE-2 antibody; ESE2 antibody; Ets domain TF antibody; Ets domain transcription factor antibody; ETS related transcription factor Elf 5 antibody; ETS related transcription factor Elf5 antibody; ETS-related transcription factor Elf-5 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the C-terminal region of Human Elf-5.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation.; Isoform 2 binds to DNA sequences containing the consensus nucleotide core sequence GGA[AT]. Transcriptionally activates SPRR2A and the parotid gland-specific PSP promoters.
  • 基因功能參考文獻:
    1. Elf5 expression was associated with decreased overall and disease-free survival of triple negative breast cancers patients. PMID: 29396764
    2. When ELF5 was transfected into the parental MCF7 cells that lack CEACAM1, lumen formation was restored, indicating that ELF5 can replace CEACAM1 in this model system of lumenogenesis. PMID: 28800960
    3. These results support the contention that ABO expression is dependent upon a downstream positive regulatory element functioning through a tissue-restricted transcription factor, Elf5, in epithelial cells. PMID: 27587399
    4. Low ELF5 expression is associated with ovarian cancer. PMID: 28184931
    5. The results of this study suggest that ELF5 is a candidate gene that confers genetic susceptibility for pediatric asthma in the Taiwanese population and SNP rs3910901 may have a minor impact on pediatric asthma in the Taiwanese population. PMID: 25648666
    6. a novel EWSR1/ETS chimeric gene, was identified in a patient diagnosed with refractory AML, suggesting a potential role of leukemogenesis in rare cases of AML. This fusion gene is very likely to exhibit oncogenic potential by interfering with the p53/p21-dependent pathway. PMID: 27627705
    7. Alternative promoter use, conferring differential regulatory responses, is the main mechanism governing ELF5 action rather than differential transcriptional activity of the isoforms. PMID: 26738740
    8. Data (including data from studies in transgenic mice) suggest that expression of ELF5 in luminal breast cancer correlates with increased myeloid cell invasion, inflammation, and lung metastasis. PMID: 26717410
    9. we identified Elf5 as a novel biomarker of urothelial cancer on several biological levels and established a causative link between Elf5 and epithelial-mesenchymal transition in urothelial cancer. PMID: 25629735
    10. Elf5 expression is inversely correlated with epithelial-mesenchymal transition in prostate cancer. PMID: 25728398
    11. ELF5 provides a key transcriptional determinant of breast cancer molecular subtype by suppression of estrogen sensitivity in luminal breast cancer cells. PMID: 23300383
    12. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. PMID: 23086238
    13. Loss of ELF5 is associated with kidney cancer. PMID: 21787113
    14. ELF5 is expressed in the human placenta in villous cytotrophoblast cells but not in post-mitotic syncytiotrophoblast and invasive extravillous cytotrophoblast cells. PMID: 20354077
    15. findings show that Ese-2 upregulates K18 gene expression through specific interactions within ETS binding sites in the regulatory first intron of the gene PMID: 15987600
    16. Our studies have identified a critical stretch of nucleotides that is important for both basal as well as calcium responsive reporter activity and that binds to a nuclear factor, keratinocyte restricted factor (KRF). PMID: 16229011
    17. Identification of the ESE-2 consensus site and characterization of the transcriptional activation properties of ESE-2 shed new light on its potential as a regulator of target genes. PMID: 16704374

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    ETS family
  • 組織特異性:
    Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tiss
  • 數據庫鏈接:

    HGNC: 3320

    OMIM: 605169

    KEGG: hsa:2001

    STRING: 9606.ENSP00000311010

    UniGene: Hs.11713



主站蜘蛛池模板: 国产精品无码一本二本三本色 | 国产麻豆精品福利在线| 波多野结衣av高清一区二区三区| 欧美成人国产精品高潮| 久久99国产精品久久99果冻传媒| 国产欧美va欧美va香蕉在线观看| 欧美人与动牲交app视频| 亚洲精品一区久久久久| 欧美日韩色另类综合| 国产精品久久福利网站| 国产在线码观看清码视频| 久久中文字幕人妻熟女| 97精品人人a片免费看| 国内精品久久久久影院薰衣草| 天天躁日日躁aaaxxⅹ| 欧美午夜成人片在线观看| 国产精品白丝喷水在线观看| 亚洲va中文字幕无码久久| 人妻老妇乱子伦精品无码专区| 女女女女女裸体处开bbb| 俺也来俺也去俺也射| 亚洲mv国产mv在线mv综合试看| 伊人久久大香线蕉综合影院首页| 东京热久久综合久久88| 国产综合精品一区二区三区 | 三男一女吃奶添下面视频| 国产成人亚洲高清一区| 久久精品女同亚洲女同| 日韩av午夜在线观看| 欧美野外疯狂做受xxxx高潮| 国产精品乱子伦xxxx| 伦埋琪琪久久影院三级| 扒开双腿吃奶呻吟做受视频| 亚洲中文字幕在线无码一区二区| 成人免费午夜无码视频| 日本高清视频在线www色| 永久免费精品精品永久-夜色| 色综合欧美五月俺也去| 国产精品无码aⅴ嫩草| 99久久久无码国产精品免费| 亚洲国产超清无码专区|