在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EHD3 Antibody

EHD3 Antibody

  • 中文名稱：
    EHD3兔多克隆抗體
  • 貨號：
    CSB-PA878940LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA878940LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA878940LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA878940LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) EHD3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    EHD3 antibody; EHD2 antibody; PAST3EH domain-containing protein 3 antibody; PAST homolog 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human EH domain-containing protein 3 protein (269-498AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，EHD3 Antibody (CSB-PA878940LA01HU)，的標記方式是Non-conjugated。對于EHD3 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA878940LB01HU EHD3 Antibody, HRP conjugated ELISA
    FITC CSB-PA878940LC01HU EHD3 Antibody, FITC conjugated
    Biotin CSB-PA878940LD01HU EHD3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity. Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology. Involved in the recycling of internalized D1 dopamine receptor. Plays a role in cardiac protein trafficking probably implicating ANK2. Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction. In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function. Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis; possibly sharing redundant functions with EHD1.
  • 基因功能參考文獻：
    1. Data provide evidence that EHD3 might undergo its tumor suppressor functions at least in part through promoting the sorting of activated EGFR to the lysosomal degradative compartment and spatio-temporal regulation of EGFR signaling via ERK and AKT. PMID: 27811356
    2. the residues Ala-519/Asp-520 of EHD1 and Asn-519/Glu-520 of EHD3 as defining the selectivity of these two paralogs for NPF-containing binding partners PMID: 27189942
    3. The EHD3 gene may be associated with the endophenotype of cognitive function in major depressive disorder patients. PMID: 24997812
    4. 3 SNPs present in the EHD3 gene, of which rs619002 and rs644926 were exclusively associated with female major depressive disorder PMID: 24607927
    5. demonstrate Ehd3 growth inhibitory functions in glioma cells in vivo. We suggest that Ehd3 functions as a tumor suppressor gene and loss of its expression is a very common event in gliomas PMID: 24306026
    6. The combined effect of the EHD3 and FREM3 genes may play an important role in developing major depressive disorder. PMID: 22337703
    7. EHD3 is a previously unrecognized component of the cardiac remodeling pathway in heart failure. PMID: 22406195
    8. presented herein promote a coordinated role for EHD proteins and Rab11-FIP2 in mediating endocytic recycling and provide evidence for the function of EHD3 in early endosome to endocytic recycling compartment transport PMID: 16251358
    9. Our findings support a role for EHD3 in regulating endosome-to-Golgi transport, and as a consequence, lysosomal biosynthetic, but not secretory, transport pathways are also affected PMID: 19139087

    顯示更多

    收起更多

  • 亞細胞定位：
    Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family, EHD subfamily
  • 組織特異性：
    Highly expressed in heart and brain and moderately expressed in kidney, liver, and placenta.
  • 數據庫鏈接：

    HGNC: 3244

    OMIM: 605891

    KEGG: hsa:30845

    STRING: 9606.ENSP00000327116

    UniGene: Hs.368808



主站蜘蛛池模板： 日本老熟妇乱子伦视频| 国产成人精品福利网站| 免费情侣作爱视频| 日韩免费无码视频一区二区三区| 欧美综合在线激情专区| 18禁高潮出水呻吟娇喘蜜芽| 在线播放无码后入内射少妇| 国产主播一区二区三区在线观看| 久久国产乱子伦精品免费台湾 | 久久99精品国产麻豆蜜芽| 亚洲欧美综合成人五月天网站 | 亚洲国产精品成人综合色| 久久精品第九区免费观看| 99久久婷婷国产综合精品青草免费| 中文字幕乱码无码人妻系列蜜桃| 吃奶摸下高潮60分钟免费视频| 人妻熟女一区二区aⅴ清水理纱 | 国产精品性夜天天拍拍2021| 性色av一区二区三区人妻| 亚洲va中文字幕无码毛片| 中文字幕亚洲乱码熟女在线| 欧美videos另类极品| 又粗又黄又爽视频免费看| 国产精品久久久久无码av色戒| 中文人妻无码一区二区三区| 亚洲欧美日本中文字不卡| 四虎成人精品永久在线视频| av无码精品一区二区三区| 在线涩涩免费观看国产精品| 人妻无码中文字幕永久在线 | 猫咪www免费人成网站无码| 亚洲最大无码av网站观看| 日本一区二区三区免费高清| 欧美大屁股xxxx高跟欧美黑人| 2020精品国产午夜福利在线观看| 伊人久久大香线蕉av成人| 麻豆av一区二区天美传媒| 久久久亚洲欧洲日产av| 亚洲欧美日韩国产精品一区| 久久人人爽人人爽人人片av东京热| 欧美成人看片一区二区|