在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EHD3 Antibody, Biotin conjugated

EHD3 Antibody, Biotin conjugated

  • 中文名稱：
    EHD3兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA878940LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) EHD3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    EHD3 antibody; EHD2 antibody; PAST3EH domain-containing protein 3 antibody; PAST homolog 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human EH domain-containing protein 3 protein (269-498AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. In vitro causes tubulation of endocytic membranes. Binding to phosphatidic acid induces its membrane tubulation activity. Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology. Involved in the recycling of internalized D1 dopamine receptor. Plays a role in cardiac protein trafficking probably implicating ANK2. Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction. In conjunction with EHD4 may be involved in endocytic trafficking of KDR/VEGFR2 implicated in control of glomerular function. Involved in the rapid recycling of integrin beta-3 implicated in cell adhesion maintenance. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary vesicle, an early step in cilium biogenesis; possibly sharing redundant functions with EHD1.
  • 基因功能參考文獻：
    1. Data provide evidence that EHD3 might undergo its tumor suppressor functions at least in part through promoting the sorting of activated EGFR to the lysosomal degradative compartment and spatio-temporal regulation of EGFR signaling via ERK and AKT. PMID: 27811356
    2. the residues Ala-519/Asp-520 of EHD1 and Asn-519/Glu-520 of EHD3 as defining the selectivity of these two paralogs for NPF-containing binding partners PMID: 27189942
    3. The EHD3 gene may be associated with the endophenotype of cognitive function in major depressive disorder patients. PMID: 24997812
    4. 3 SNPs present in the EHD3 gene, of which rs619002 and rs644926 were exclusively associated with female major depressive disorder PMID: 24607927
    5. demonstrate Ehd3 growth inhibitory functions in glioma cells in vivo. We suggest that Ehd3 functions as a tumor suppressor gene and loss of its expression is a very common event in gliomas PMID: 24306026
    6. The combined effect of the EHD3 and FREM3 genes may play an important role in developing major depressive disorder. PMID: 22337703
    7. EHD3 is a previously unrecognized component of the cardiac remodeling pathway in heart failure. PMID: 22406195
    8. presented herein promote a coordinated role for EHD proteins and Rab11-FIP2 in mediating endocytic recycling and provide evidence for the function of EHD3 in early endosome to endocytic recycling compartment transport PMID: 16251358
    9. Our findings support a role for EHD3 in regulating endosome-to-Golgi transport, and as a consequence, lysosomal biosynthetic, but not secretory, transport pathways are also affected PMID: 19139087

    顯示更多

    收起更多

  • 亞細胞定位：
    Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family, EHD subfamily
  • 組織特異性：
    Highly expressed in heart and brain and moderately expressed in kidney, liver, and placenta.
  • 數據庫鏈接：

    HGNC: 3244

    OMIM: 605891

    KEGG: hsa:30845

    STRING: 9606.ENSP00000327116

    UniGene: Hs.368808



主站蜘蛛池模板： 无码人妻熟妇av又粗又大| 成人精品视频一区二区三区| 麻豆av一区二区三区久久| 久99久热只有精品国产女同 | 中文字幕亚洲欧美在线不卡| 青春草在线视频观看| 性欧美大胆免费播放| 色综合久久精品亚洲国产| 色综合天天视频在线观看| 亚洲一码二码三码精华液| 久久欧美一区二区三区性牲奴| 又黄又爽的60分钟视频| 日韩免费视频| 俺也来俺也去俺也射| 极品粉嫩国产18尤物在线观看| 手机看黄av免费网址| 2018高清国产一区二区三区| 欧洲精品一线二线三线区别| 窝窝午夜色视频国产精品破| 少妇被黑人到高潮喷出白浆| 亚洲欧美日韩视频高清专区 | 久久久中日ab精品综合| аⅴ资源天堂资源库在线| 人妻熟女一区二区aⅴ林晓雪| av无码人妻一区二区三区牛牛| 亚洲va在线va天堂va欧美va| 欧美xxxx做受欧美人妖| 国产极品粉嫩泬免费观看| 欧美性大战久久久久久久| 噜噜噜av久久av苍井空| 骚动漫十八禁在线观看| 99久久亚洲精品日本无码| 国内精品久久毛片一区二区| 无码人妻丰满熟妇精品区| 18禁真人抽搐一进一出在线| 午夜国产亚洲精品一区| 久久天天躁狠狠躁夜夜avapp| 国产精品无码一本二本三本色| 久久人妻少妇嫩草av无码专区| 国产在线精品一区二区| 少妇夜夜春夜夜爽试看视频|