在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EFHD2 Antibody

EFHD2 Antibody

  • 中文名稱：
    EFHD2兔多克隆抗體
  • 貨號：
    CSB-PA007458GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    EFHD2
  • 別名：
    EF hand domain containing protein 2 antibody; EF hand domain family; member D2 antibody; EF-hand domain-containing protein D2 antibody; EFHD 2 antibody; EFHD2 antibody; EFHD2_HUMAN antibody; RP3-467K16.3 antibody; Swiprosin 1 antibody; Swiprosin-1 antibody; SWS1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human EFHD2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
  • 基因功能參考文獻：
    1. Data demonstrate that EFhd2 shows unique structural and biological features as an EF-hand containing F-actin bundling protein. For F-actin bundling activity, structural stabilization of the EF-hand domains was found to occur in the presence of Ca2+. The core region of EFhd2 maintains its structure in the absence of Ca2+ ; however, changes in local conformational flexibility reduce F-actin bundling activity of EFhd2. PMID: 27974828
    2. Phosphorylation at Ser183 of EFhd2 causes changes in the local conformational dynamics and the surface charge distribution of the actin-binding site, resulting in a re-coordination of the actin-binding sites in the dimer structure. PMID: 28011271
    3. The results imply that EFhd2's physiological and/or pathological function could be regulated by its phosphorylation state. PMID: 24917152
    4. EFhd2 is involved in the control of synapse development and maintenance and is linked to dementia. PMID: 25383639
    5. Swiprosin-1 localizes to microvilli-like membrane protrusions and lamellipodia and exhibits actin-binding activity. PMID: 23977092
    6. Swiprosin-1 is involved in regulating the accessibility of F-actin to cofilin through the clustering of F-actin and the activity of Swiprosin-1 is highly dependent on its phosphorylation status at Ser183 PMID: 23959172
    7. EFhd2 may play an important role in the pathobiology of tau-mediated neurodegeneration. PMID: 23331044
    8. the human Shu complex (hSWS1.SWSAP1) has an evolutionarily conserved function in homologous recombination PMID: 21965664
    9. This protein has been found differentially expressed in thalami from patients with schizophrenia. PMID: 20471030
    10. Its predominant presence in CD8 lymphocytes suggests that swiprosin-1 may be involved in functions that are important for cytotoxic lymphocytes. PMID: 15274114
    11. These results suggest that swiprosin-1 is a PKC-beta I/eta-inducible gene and it modulates mast cell activation through NF-kappaB-dependent pathway. PMID: 19693767

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane raft.
  • 組織特異性：
    Found in lymphocytes; preferentially expressed in CD8+ cells.
  • 數據庫鏈接：

    HGNC: 28670

    OMIM: 616450

    KEGG: hsa:79180

    STRING: 9606.ENSP00000365147

    UniGene: Hs.465374



主站蜘蛛池模板： 专干熟肥老妇人视频在线看 | 无码精品人妻一区二区三区影院| 90后极品粉嫩小泬20p| 久久777国产线看观看精品| 国产熟女亚洲精品麻豆| 日韩欧国产精品一区综合无码| 第一亚洲中文久久精品无码| 午夜dj在线观看高清在线视频完整版| 秋霞影院午夜伦a片欧美| 香蕉久久福利院| 青春草在线视频免费观看| 中文字幕v亚洲日本在线| 国产在线清纯极品美女援交| 成人午夜特黄aaaaa片男男| 性一交一乱一伦一色一情孩交| 美女黄18以下禁止观看| 怡春院国产精品视频| 成人免费视频在线观看地区免下载| 99久久久国产精品消防器材| 无码播放一区二区三区| 欧美性xxxxx极品娇小| 好男人社区神马在线观看www| 欧美品无码一区二区三区在线蜜桃 | 亚洲妇女水蜜桃av网网站| 亚洲欧洲无码av不卡在线| 无码纯肉动漫在线观看| 成年女人黄小视频| 日日碰狠狠躁久久躁蜜桃| 成人伊人亚洲人综合网站| 成年女人永久免费看片| 国语自产精品视频在线第100页| 大胆欧美熟妇xxbbwwbw高潮了| 亚洲欧美一区二区成人片| 久久久久国产精品人妻aⅴ院| 国产精品一区在线蜜臀| 久久国产加勒比精品无码| 欧美老熟妇videos极品另类| 羞羞视频在线观看| 在线观看国产日韩亚洲中| 亚洲欧洲日韩综合久久| 黑人粗硬进入过程视频|