在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. EFHD2 Antibody, FITC conjugated

EFHD2 Antibody, FITC conjugated

  • 中文名稱：
    EFHD2兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA856907LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) EFHD2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    EFHD2
  • 別名：
    EF hand domain containing protein 2 antibody; EF hand domain family; member D2 antibody; EF-hand domain-containing protein D2 antibody; EFHD 2 antibody; EFHD2 antibody; EFHD2_HUMAN antibody; RP3-467K16.3 antibody; Swiprosin 1 antibody; Swiprosin-1 antibody; SWS1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human EF-hand domain-containing protein D2 protein (2-240AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
  • 基因功能參考文獻：
    1. Data demonstrate that EFhd2 shows unique structural and biological features as an EF-hand containing F-actin bundling protein. For F-actin bundling activity, structural stabilization of the EF-hand domains was found to occur in the presence of Ca2+. The core region of EFhd2 maintains its structure in the absence of Ca2+ ; however, changes in local conformational flexibility reduce F-actin bundling activity of EFhd2. PMID: 27974828
    2. Phosphorylation at Ser183 of EFhd2 causes changes in the local conformational dynamics and the surface charge distribution of the actin-binding site, resulting in a re-coordination of the actin-binding sites in the dimer structure. PMID: 28011271
    3. The results imply that EFhd2's physiological and/or pathological function could be regulated by its phosphorylation state. PMID: 24917152
    4. EFhd2 is involved in the control of synapse development and maintenance and is linked to dementia. PMID: 25383639
    5. Swiprosin-1 localizes to microvilli-like membrane protrusions and lamellipodia and exhibits actin-binding activity. PMID: 23977092
    6. Swiprosin-1 is involved in regulating the accessibility of F-actin to cofilin through the clustering of F-actin and the activity of Swiprosin-1 is highly dependent on its phosphorylation status at Ser183 PMID: 23959172
    7. EFhd2 may play an important role in the pathobiology of tau-mediated neurodegeneration. PMID: 23331044
    8. the human Shu complex (hSWS1.SWSAP1) has an evolutionarily conserved function in homologous recombination PMID: 21965664
    9. This protein has been found differentially expressed in thalami from patients with schizophrenia. PMID: 20471030
    10. Its predominant presence in CD8 lymphocytes suggests that swiprosin-1 may be involved in functions that are important for cytotoxic lymphocytes. PMID: 15274114
    11. These results suggest that swiprosin-1 is a PKC-beta I/eta-inducible gene and it modulates mast cell activation through NF-kappaB-dependent pathway. PMID: 19693767

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane raft.
  • 組織特異性：
    Found in lymphocytes; preferentially expressed in CD8+ cells.
  • 數據庫鏈接：

    HGNC: 28670

    OMIM: 616450

    KEGG: hsa:79180

    STRING: 9606.ENSP00000365147

    UniGene: Hs.465374



主站蜘蛛池模板： 极品无码国模国产在线观看| 国产成人综合久久久久久| 久久久久日韩精品免费观看| 狠狠色狠狠色狠狠五月| 好爽又高潮了毛片免费下载| 国产成人一区二区三区影院动漫| 中文字幕人成乱码熟女香港 | 老子影院午夜精品无码| 无码国产激情在线观看| 又粗又黄又猛又爽大片免费| 熟妇人妻系列av无码一区二区| 欧美人与物videos另类xxxxx| 2018亚洲а∨天堂| 综合色就爱涩涩涩综合婷婷| 免费三级网站| 国产内射999视频一区| 成人无码av一区二区三区| 无码午夜福利免费区久久| 粗大猛烈进出高潮视频免费看| www亚洲精品久久久乳| 无人区一线二线三线乱码| 图片区 小说区 区 亚洲五月| 最新国产乱人伦偷精品免费网站| 免费人成视频网站在线观看18| 大伊香蕉精品一区二区| 伊人久久精品一区二区三区| 国产精品成人a区在线观看| 亚洲成在人线在线播放无码vr| 国产欧美日韩精品丝袜高跟鞋| 无码av大香线蕉| 亚洲高清国产av拍精品青青草原| 欧美乱码卡一卡二卡四卡免费| 日韩一欧美内射在线观看| 亚洲熟妇无码久久精品| 体验区试看120秒啪啪免费| 男人添女人囗交做爰视频| 中文在线а√在线| 日本一区二区三区免费播放视频站| 亚洲成av人片一区二区三区| 国产精品久久久久av福利动漫| 午夜福利18以下勿进免费|