在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EEA1 Antibody, Biotin conjugated

  • 中文名稱:
    EEA1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA007405LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) EEA1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Early endosome antigen 1 antibody; Early endosome antigen 1; 162kD antibody; Early endosome associated protein antibody; EEA 1 antibody; EEA1 antibody; EEA1_HUMAN antibody; Endosome associated protein p162 antibody; Endosome-associated protein p162 antibody; MST105 antibody; MSTP105 antibody; ZFYVE2 antibody; Zinc finger FYVE domain containing protein 2 antibody; Zinc finger FYVE domain-containing protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Early endosome antigen 1 protein (734-875AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.
  • 基因功能參考文獻:
    1. This also suggests that this pathway is involved in EEA1-vesicles biogenesis. PMID: 30188634
    2. identification of allergic bronchopulmonary aspergillosis -associated variants in EEA that have functional effects on macrophage phagocytosis and phagolysosome acidification of A. fumigatus conidia. PMID: 29547649
    3. results suggest a new mechanism in which Rab5 induces a change in flexibility of EEA1, generating an entropic collapse force that pulls the captured vesicle towards the target membrane to initiate docking and membrane fusion PMID: 27556945
    4. EEA1 mobility on endosomes is decreased upon stimulation of EGF receptor endocytosis in HeLa cells PMID: 26993163
    5. Under the regulation of Rab5, the fused vesicles are targeted to early endosomes and thus deliver the internalized TbetaRI to the caveolin-1 and EEA1 double-positive early endosomes (caveolin-1-positive early endosomes). PMID: 25998683
    6. In serum-deprivated HeLa cells with low endocytic activity there two types of EEA1-vesicles: the first one carries the both EEA1 and Rab5 at high levels; the second consists of weakly decorated EEA1-vesicles that can be both Rab5-positive and -negative. PMID: 25711083
    7. Data indicate that early endosome antigen 1 (EEA1) is important for the small GTPase Rab31-mediated enhancement of ligand-bound EGF receptor (EGFR) endocytic trafficking. PMID: 24644286
    8. nuclear uptake of Abeta involves the dynamin-dependent EEA1 and TGF-beta/Smad signaling pathways. PMID: 24491918
    9. We therefore propose that the N1072K variant of the EEA1 gene is a candidate mutation for susceptibility to diabetes in the Japanese population. PMID: 23499280
    10. EEA1 interacts with Phafin2 and colocolizes with Phafin2 in endosome membrane. PMID: 22816767
    11. NMR analyses of the interaction between the FYVE domain of early endosome antigen 1 (EEA1) and phosphoinositide embedded in a lipid bilayer. PMID: 22915584
    12. p97 inhibition causes increased EEA1 self-association at the endosome membrane. PMID: 21556036
    13. The knockdown of STEAP4 inhibits insulin-stimulated glucose transport and GLUT4 translocation via the attenuated phosphorylation of Akt, independent of the effects of EEA1. PMID: 21468601
    14. crystal structure of Rab5A in complex with the EEA1 C(2)H(2) zinc finger PMID: 20534488
    15. activation of p38 MAPK caused a decrease in EEA1 colocalization with phagosomes, arresting maturation into the phagolysosome PMID: 12963735
    16. macropinosomes do not mature to late endosomes or fuse with lysosomes. EEA1 continuously mediates homotypic fusion as long as the macropinosomes persist. PMID: 15052657
    17. These results suggest that EEA1 is involved in neuronal synaptic vesicle function and axonal transport and growth. EEA1 may undergo calcium-dependent conformational changes that are required for binding to SNAP-25. PMID: 15451443
    18. Results describe the geometry of the micelle penetration of the early endosome antigen 1 FYVE domain. PMID: 16331966
    19. PIKfyve is distributed in microdomains that are distinct from those occupied by EEA1 and Hrs PMID: 16448788
    20. Impairment of internalization of specific glutamate receptors and their subsequent accumulation in the synapse may account for the neurological deficits observed in some patients developing EEA1 autoantibodies. PMID: 17113235
    21. results suggest that the local production of PtdIns(3)P implicates the fusion of macropinosomes via EEA1 as well as conventional early endosomes PMID: 17146146

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Early endosome membrane; Peripheral membrane protein.
  • 數據庫鏈接:

    HGNC: 3185

    OMIM: 605070

    KEGG: hsa:8411

    STRING: 9606.ENSP00000317955

    UniGene: Hs.567367



主站蜘蛛池模板: 久久成人国产精品| 国产免费爽爽视频在线观看| 国产午夜无码片免费| 亚洲最大成人网 色香蕉| 日产精品久久久久久久| 97香蕉碰碰人妻国产欧美| 亚洲色大成网站www永久一区| 无码熟妇人妻av在线影片免费| 国产免费午夜a无码v视频| 欧美成人免费一区二区| 久久先锋男人av资源网站| 美女人妻激情乱人伦| 18禁成人黄网站免费观看久久| 美女脱了内裤张开腿让男人桶网站 | 欧美日韩国产一区二区三区不卡| 天天综合网久久综合免费人成 | 在线视频观看免费视频18| 18禁裸体女免费观看| 97成人精品国语自产拍| 亚州性无码不卡免费视频| 国产a∨精品一区二区三区不卡| 午夜寂寞少妇aaa片毛片| 国产精品国产av片国产| 久久免费精品国产72精品九九| 久久久精品人妻无码专区不卡| 十八禁视频网站在线观看| 色欲av永久无码精品无码| 67pao国产成视频永久免费| 国产精品毛片无码| 国自产拍偷拍精品啪啪模特| 国产成人亚洲日韩欧美| 亚洲精品国产av成拍色拍婷婷| 成人精品一区二区三区电影| 2022久久国产精品免费热麻豆| 亚洲国产成人无码av在线播放| 久久精品久久久久观看99水蜜桃| 成年无码av片在线| 久久久国产99久久国产久麻豆| 国产黄在线观看免费观看软件| 艳妇乳肉豪妇荡乳av| 久久精品国产9久久综合|