在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DUSP12 Antibody

DUSP12 Antibody

  • 中文名稱：
    DUSP12兔多克隆抗體
  • 貨號：
    CSB-PA774733
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA774733(DUSP12 Antibody) at dilution 1/77, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    DUSP12
  • 別名：
    Dual specificity phosphatase 12 antibody; Dual specificity protein phosphatase 12 antibody; Dual specificity tyrosine phosphatase YVH1 antibody; DUS12_HUMAN antibody; DUSP 1 antibody; DUSP 12 antibody; DUSP1 antibody; DUSP12 antibody; Serine/threonine specific protein phosphatase antibody; TDSP4 antibody; YVH 1 antibody; YVH1 antibody; YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog antibody; YVH1 protein tyrosine phosphatase ortholog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human DUSP12
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Can dephosphorylate glucokinase (in vitro). Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate and other in vitro substrates.
  • 基因功能參考文獻：
    1. Results from a study on gene variability markers in early-stage human embryos shows that DUSP12 is a putative variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
    2. A significant decrease in DUSP12 expression in hypertrophic hearts and cardiomyocytes. PMID: 27702885
    3. These results propagate a role for dual specificity phosphatases at RNP particles and suggest that hYVH1 may affect a variety of fundamental cellular processes by regulating messenger ribonucleoprotein (mRNP) dynamics. PMID: 27856639
    4. hYVH1 is a novel modulator of cell cycle progression mediated by a phosphorylation site located at the C-terminal end of the zinc-binding domain PMID: 21521943
    5. propose that the BRC repeats in BRCA2 cooperate in a partially redundant but reinforcing manner to ensure a high probability of RAD51 filament formation PMID: 21556130
    6. these data suggests common SNPs within DUSP12-ATF6 locus may not play a major role in glucose metabolism in the Chinese. PMID: 21211013
    7. tudies confirmed elevated expression of three target antigens RAB38, TBCE, and DUSP12 in CML. PMID: 20103624
    8. Our data suggest that sequences in or upstream of DUSP12 may contribute to type 2 diabetes susceptibility, but the lack of replication suggests a small effect size. PMID: 16936214
    9. hYVH1 is a novel cell survival phosphatase that co-operates with Hsp70 to positively affect cell viability in response to cellular insults. PMID: 18973475
    10. Data determined that hYVH1 forms intramolecular disulfide bonds at the catalytic cleft as well as within the zinc binding domain to avoid irreversible inactivation during severe oxidative stress. PMID: 19567874

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm, cytosol.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
  • 組織特異性：
    Ubiquitous, highest expression in spleen, testis, ovary, and peripheral blood leukocytes and lower expression in liver and lung.
  • 數據庫鏈接：

    HGNC: 3067

    OMIM: 604835

    KEGG: hsa:11266

    STRING: 9606.ENSP00000356920

    UniGene: Hs.416216



主站蜘蛛池模板： 国产精品最新免费视频| 婷婷五月综合丁香在线| 国产va免费精品观看| 亚洲va中文字幕无码久久不卡| 一边捏奶一边高潮视频| 国产精品久久久久蜜芽| 国产精品偷窥熟女精品视频| 狂野欧美性猛交免费视频| а√天堂资源中文在线官网| 春药玩弄少妇高潮吼叫| 精品国产一区二区三区av色诱| 宝贝腿开大点我添添公视频免费| 亚洲日韩精品无码专区| 久热国产vs视频在线观看 | 欧美拍拍视频免费大全| 午夜裸体性播放| 大香线蕉伊人精品超碰| 久久国产偷任你爽任你| 亚洲图片综合图区20p| 性少妇中国内射xxxx狠干| 天天爽天天爽夜夜爽毛片| 中国性少妇内射xxxx狠干| 亚洲国产精品av在线播放| 大香伊人久久精品一区二区| 天天躁日日躁狠狠躁欧美老妇小说| 日韩人妻无码一区二区三区久久99 | 丰满人妻熟妇乱偷人无码| 老妇高潮潮喷到猛进猛出| 午夜电影网va内射| 50岁熟妇的呻吟声对白| 女人高潮抽搐喷液30分钟视频| 中文在线√天堂| 免费看女人与善牲交| 欲女熟妇国产一区二区| 欧美日韩亚洲国产精品| 欧美乱妇狂野欧美在线视频| 2018天天躁夜夜躁狠狠躁| 猫咪免费人成网站在线观看| 国内精品久久久久影院一蜜桃| 日本大乳高潮视频在线观看| 国产亚洲精品福利在线无卡一|