在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DUSP12 Antibody

DUSP12 Antibody

  • 中文名稱：
    DUSP12兔多克隆抗體
  • 貨號(hào)：
    CSB-PA229389
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA229389(DUSP12 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: CSB-PA229389(DUSP12 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    DUSP12
  • 別名：
    Dual specificity phosphatase 12 antibody; Dual specificity protein phosphatase 12 antibody; Dual specificity tyrosine phosphatase YVH1 antibody; DUS12_HUMAN antibody; DUSP 1 antibody; DUSP 12 antibody; DUSP1 antibody; DUSP12 antibody; Serine/threonine specific protein phosphatase antibody; TDSP4 antibody; YVH 1 antibody; YVH1 antibody; YVH1 protein tyrosine phosphatase (S. cerevisiae) ortholog antibody; YVH1 protein tyrosine phosphatase ortholog antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human DUSP12
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. Can dephosphorylate glucokinase (in vitro). Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate and other in vitro substrates.
  • 基因功能參考文獻(xiàn)：
    1. Results from a study on gene variability markers in early-stage human embryos shows that DUSP12 is a putative variability marker for the 3-day, 8-cell embryo stage. PMID: 26288249
    2. A significant decrease in DUSP12 expression in hypertrophic hearts and cardiomyocytes. PMID: 27702885
    3. These results propagate a role for dual specificity phosphatases at RNP particles and suggest that hYVH1 may affect a variety of fundamental cellular processes by regulating messenger ribonucleoprotein (mRNP) dynamics. PMID: 27856639
    4. hYVH1 is a novel modulator of cell cycle progression mediated by a phosphorylation site located at the C-terminal end of the zinc-binding domain PMID: 21521943
    5. propose that the BRC repeats in BRCA2 cooperate in a partially redundant but reinforcing manner to ensure a high probability of RAD51 filament formation PMID: 21556130
    6. these data suggests common SNPs within DUSP12-ATF6 locus may not play a major role in glucose metabolism in the Chinese. PMID: 21211013
    7. tudies confirmed elevated expression of three target antigens RAB38, TBCE, and DUSP12 in CML. PMID: 20103624
    8. Our data suggest that sequences in or upstream of DUSP12 may contribute to type 2 diabetes susceptibility, but the lack of replication suggests a small effect size. PMID: 16936214
    9. hYVH1 is a novel cell survival phosphatase that co-operates with Hsp70 to positively affect cell viability in response to cellular insults. PMID: 18973475
    10. Data determined that hYVH1 forms intramolecular disulfide bonds at the catalytic cleft as well as within the zinc binding domain to avoid irreversible inactivation during severe oxidative stress. PMID: 19567874

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm, cytosol.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
  • 組織特異性：
    Ubiquitous, highest expression in spleen, testis, ovary, and peripheral blood leukocytes and lower expression in liver and lung.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 3067

    OMIM: 604835

    KEGG: hsa:11266

    STRING: 9606.ENSP00000356920

    UniGene: Hs.416216



主站蜘蛛池模板： 特黄三级又爽又粗又大| 狂野欧美激情性xxxx| 人妻少妇中文字幕乱码| 色一情一区二区三区四区| 免费人成年激情视频在线观看| 一本色道av久久精品+网站| 三上悠亚精品一区二区久久| 3d动漫精品啪啪一区二区中| 亚欧成人中文字幕一区| 久热在线播放中文字幕| 欧美丰满老妇性猛交| 真实国产老熟女无套中出| 国产欧美高清在线观看| 日韩乱码人妻无码中文字幕久久| 青青草无码伊人久久| 国产区精品一区二区不卡中文| 一本久道综合色婷婷五月| 日韩精品久久无码人妻中文字幕| 国产精品乱码人妻一区二区三区 | 欧美日韩精品一区二区性色a+v | 人与禽性视频77777| 欧美嫩交一区二区三区| 亚洲人成77777在线播放网站不卡| 亚洲色无码中文字幕yy51999| 无码av高潮抽搐流白浆| 激情五月色综合国产精品| 日韩69永久免费视频| 中文在线www天堂网| 亚洲国产av美女网站| 熟睡人妻被讨厌的公侵犯深田咏美 | 人妻饥渴偷公乱中文字幕| 日韩精品一区二区三区中文| 一本天堂v无码亚洲道久久| 国产真实乱对白精彩久久| 亚洲欧美在线观看| 国内精品国产三级国产av| 狠狠色丁香婷婷综合尤物| 男女午夜猛烈啪啦啦视频| 国产精品福利视频导航| 欧美黑人添添高潮a片www| 日本在线高清不卡免费播放|