在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DRG1 Antibody

  • 中文名稱:
    DRG1兔多克隆抗體
  • 貨號:
    CSB-PA007185GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    DRG1
  • 別名:
    Developmentally regulated GTP binding protein 1 antibody; Developmentally-regulated GTP-binding protein 1 antibody; DKFZp434N1827 antibody; DRG 1 antibody; DRG-1 antibody; DRG1 antibody; DRG1_HUMAN antibody; NEDD 3 antibody; NEDD-3 antibody; NEDD3 antibody; Neural precursor cell expressed developmentally down regulated protein 3 antibody; Neural precursor cell expressed developmentally down-regulated protein 3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human DRG1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions.
  • 基因功能參考文獻:
    1. DRG1 was an important protein involved in spindle checkpoint signaling, and elevated levels of DRG1 caused lung adenocarcinoma and taxol resistance. PMID: 27626498
    2. DRG-1 plays an important role in melanoma cell growth and transformation, indicating that DRG1 may represent a novel target for CD4(+) T cell-mediated immunotherapy in melanoma. PMID: 25993655
    3. Lerepo4 action leaves Drg1 affinity for nucleotides unaffected, feasibly favoring a switch I reorientation, mainly via the TGS domain. PMID: 23711155
    4. Drg-1 is a candidate metastasis suppressor gene for prostate cancer and may serve as a useful prognostic marker. PMID: 12702552
    5. our results strongly suggest functional involvement of the Drg-1 gene in suppressing the metastatic advancement of human breast cancer. PMID: 15184886
    6. The tumor metastasis suppressor gene Drg-1 suppresses metastasis of prostate tumor cells by inhibiting the invasive ability of the cells via down-regulation of the expression of the ATF3 gene. PMID: 17178897

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm. Note=The DRG1-ZC3H15/DFRP1 complex associates with polysomes.
  • 蛋白家族:
    TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family
  • 組織特異性:
    High levels in skeletal muscle, heart, and kidney. Intermediate levels in liver, placenta and brain. Low levels in colon, thymus, spleen, small intestine, lung and leukocytes.
  • 數據庫鏈接:

    HGNC: 3029

    OMIM: 603952

    KEGG: hsa:4733

    STRING: 9606.ENSP00000329715

    UniGene: Hs.115242



主站蜘蛛池模板: 人人妻人人爽人人爽| 无码 人妻 在线 视频| 狠狠五月深爱婷婷网| 久久久久精品无码一区二区三区| 免费能直接看黄的视频| 久久精品人人做人人爽97| 人与性动交aaaabbbb| 精品国产一区二区三区四区vr| 国产av天堂无码一区二区三区| 午夜福利一区二区三区高清视频 | 国产av人人夜夜澡人人爽麻豆| 欧美内射rape视频| 亚洲a片国产av一区无码| 亚洲精品色播一区二区| 日本xxxx少妇高清hd| 女人被狂躁的高潮免费视频| 人妻精油按摩bd高清中文字幕| 日产国产精品亚洲系列| 欧美亚洲色欲色一欲www| 国产在线视频一区二区三区98| 免费又黄又硬又爽大片| 精品丝袜人妻久久久久久| 亚洲444kkkk在线观看| 欧美综合在线激情专区| 中文字幕日韩欧美一区二区三区| 怡春院国产精品视频| 欧美精品黑人粗大破除| 嫩草国产露脸精品国产软件| 成年美女黄网站色大片免费看| 亚洲性无码av中文字幕| 国色天香精品一卡2卡3卡4| 玩弄少妇人妻中文字幕| 动漫av网站免费观看| 与子敌伦刺激对白播放的优点| 天堂va欧美va亚洲va好看va| 中日韩产精品1卡二卡三卡| 午夜dv内射一区区| 婷婷丁香六月激情综合在线人| 中文无码第3页不卡av| 无码丰满少妇2在线观看| 国产欧美久久一区二区三区|