在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DPP8 Antibody

  • 中文名稱:
    DPP8兔多克隆抗體
  • 貨號:
    CSB-PA744278ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA744278ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA744278ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DPP8 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DPP8
  • 別名:
    Dipeptidyl peptidase 8 antibody; Dipeptidyl peptidase IV-related protein 1 antibody; Dipeptidyl peptidase VIII antibody; Dipeptidylpeptidase 8 antibody; DP8 antibody; DPP VIII antibody; Dpp8 antibody; DPP8_HUMAN antibody; DPRP-1 antibody; DPRP1 antibody; EC 3.4.14.5 antibody; MSTP141 antibody; Prolyl dipeptidase DPP8 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Dipeptidyl peptidase 8 protein (10-230AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2 (Probable). Acts as an inhibitor of caspase-1-dependent monocyte and macrophage pyroptosis: inhibits pyroptosis by preventing activation of NLRP1 and CARD8 via an unknown mechanism.
  • 基因功能參考文獻:
    1. The DPP8 expressing cell model system is a very useful and promising system for investigating the selectivity and associated toxicity of DPP4 inhibitors on DPP8. PMID: 25464020
    2. The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9. PMID: 24072711
    3. Suggest roles for DPP8 and DPP9 in lymphocyte activation and apoptosis and in hepatocytes during liver disease pathogenesis. PMID: 23704821
    4. DPP8 was found in macrophages of carotid atherosclerotic plaque and may play a role in disease progression. PMID: 23608773
    5. analysis of dipeptidyl peptidases 8 and 9 reveals that they may have compensatory roles PMID: 23519473
    6. this study demonstrates for the first time that DP8 and DP9 are expressed in breast and ovarian carcinoma cell lines PMID: 22736146
    7. Data identify modification points in the topology of a representative DPP8/9-inhibitor, capable of rendering selectivity for DPP8 over DPP9. PMID: 21711053
    8. This is the first study to demonstrate the presence of DP8 in chronic lymphocytic leukemia (CLL) and the upregulation of DP8 mRNA in CLL. PMID: 20534982
    9. DPP8 and DPP9 prevail over canonical DPP-IV/CD26 and FAPalpha in all examined meningioma patients PMID: 20043068
    10. cells overexpressing DP8 exhibit behavioral changesin the presence of ECM components; these effects were independent of enzyme activity PMID: 16700509
    11. Dipeptidyl peptidase 8 and dipeptidyl peptidase 9 influence cell-extracellular matrix interactions, and thus may regulate tissue remodeling. PMID: 16704418
    12. study has identified the residues absolutely required for the optimal activity of DPP8 and its unique substrate specificity PMID: 17040910
    13. DP8 cleavage of the N-terminal two residues of IP10 (CXCL10), ITAC (CXCL11) and SDF-1 (CXCL12), is reported. PMID: 18275857
    14. DP8 and DP9 tissue and cellular expression PMID: 19581630

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Peptidase S9B family, DPPIV subfamily
  • 組織特異性:
    Ubiquitously expressed, with highest levels in testis, placenta, prostate, muscle and brain.
  • 數據庫鏈接:

    HGNC: 16490

    OMIM: 606819

    KEGG: hsa:54878

    STRING: 9606.ENSP00000339208

    UniGene: Hs.458609



主站蜘蛛池模板: 亚洲 制服丝袜 中文字幕 在线 | 国产精品美女久久久久久| 久章草在线精品视频免费观看| 久久天天躁夜夜躁狠狠综合| 日韩中文亚洲欧美视频二| 极品白嫩的小少妇| 久久综合激激的五月天| 亚洲人成无码网站18禁10| 高潮迭起av乳颜射后入| 欧美s码亚洲码精品m码| 柠檬福利精品视频导航| 色欲色香天天天综合网站| 精品动漫一区二区无遮挡| 久久久久亚洲精品无码网址| 亚洲精品自产拍在线观看| 欧美日韩人妻精品一区二区在线| 国产乱码精品一区二区三区四川人| 中文字幕人成乱码熟女免费| 日韩人妻熟女中文字幕aⅴ春菜| 国产无遮挡又黄又爽动态图| 色视频www在线播放国产人成| 全黄h全肉边做边吃奶视频| 精品久久欧美熟妇www| 国产人妻精品一区二区三首| 亚洲欧美国产精品专区久久| 国产女人高潮视频在线观看| 熟睡中被义子侵犯在线播放| 猫咪免费人成网站在线观看| 精品无码人妻一区二区三区| 久久久www成人免费毛片| 窝窝午夜看片成人精品| 国产成人国产在线观看| 香港三级精品三级在线专区| 玩弄漂亮少妇高潮白浆| 又色又爽又黄还免费毛片96下载| 欧洲极品少妇| 欧美大黑帍在线播放| 狠狠色狠狠色狠狠五月| 免费人成激情视频在线观看冫| 久久综合亚洲色hezyo国产| 无码国产片观看|