在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DPP8 Antibody

  • 中文名稱:
    DPP8兔多克隆抗體
  • 貨號:
    CSB-PA007142GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    DPP8
  • 別名:
    Dipeptidyl peptidase 8 antibody; Dipeptidyl peptidase IV-related protein 1 antibody; Dipeptidyl peptidase VIII antibody; Dipeptidylpeptidase 8 antibody; DP8 antibody; DPP VIII antibody; Dpp8 antibody; DPP8_HUMAN antibody; DPRP-1 antibody; DPRP1 antibody; EC 3.4.14.5 antibody; MSTP141 antibody; Prolyl dipeptidase DPP8 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human DPP8
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2 (Probable). Acts as an inhibitor of caspase-1-dependent monocyte and macrophage pyroptosis: inhibits pyroptosis by preventing activation of NLRP1 and CARD8 via an unknown mechanism.
  • 基因功能參考文獻:
    1. The DPP8 expressing cell model system is a very useful and promising system for investigating the selectivity and associated toxicity of DPP4 inhibitors on DPP8. PMID: 25464020
    2. The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9. PMID: 24072711
    3. Suggest roles for DPP8 and DPP9 in lymphocyte activation and apoptosis and in hepatocytes during liver disease pathogenesis. PMID: 23704821
    4. DPP8 was found in macrophages of carotid atherosclerotic plaque and may play a role in disease progression. PMID: 23608773
    5. analysis of dipeptidyl peptidases 8 and 9 reveals that they may have compensatory roles PMID: 23519473
    6. this study demonstrates for the first time that DP8 and DP9 are expressed in breast and ovarian carcinoma cell lines PMID: 22736146
    7. Data identify modification points in the topology of a representative DPP8/9-inhibitor, capable of rendering selectivity for DPP8 over DPP9. PMID: 21711053
    8. This is the first study to demonstrate the presence of DP8 in chronic lymphocytic leukemia (CLL) and the upregulation of DP8 mRNA in CLL. PMID: 20534982
    9. DPP8 and DPP9 prevail over canonical DPP-IV/CD26 and FAPalpha in all examined meningioma patients PMID: 20043068
    10. cells overexpressing DP8 exhibit behavioral changesin the presence of ECM components; these effects were independent of enzyme activity PMID: 16700509
    11. Dipeptidyl peptidase 8 and dipeptidyl peptidase 9 influence cell-extracellular matrix interactions, and thus may regulate tissue remodeling. PMID: 16704418
    12. study has identified the residues absolutely required for the optimal activity of DPP8 and its unique substrate specificity PMID: 17040910
    13. DP8 cleavage of the N-terminal two residues of IP10 (CXCL10), ITAC (CXCL11) and SDF-1 (CXCL12), is reported. PMID: 18275857
    14. DP8 and DP9 tissue and cellular expression PMID: 19581630

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Peptidase S9B family, DPPIV subfamily
  • 組織特異性:
    Ubiquitously expressed, with highest levels in testis, placenta, prostate, muscle and brain.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 16490

    OMIM: 606819

    KEGG: hsa:54878

    STRING: 9606.ENSP00000339208

    UniGene: Hs.458609



主站蜘蛛池模板: 亚洲精品专区在线观看| 久9视频这里只有精品| 极品熟妇大蝴蝶20p| av亚欧洲日产国码无码| 99久久婷婷国产一区二区| 日本高清视频wwww色| 精品无码国产污污污免费网站| 欧美大屁股流白浆xxxx| aaa欧美色吧激情视频| 国产麻传媒精品国产av| 国产午夜精品一区二区| 亚洲成在人线免费观看| 体验区试看120秒啪啪免费| 香蕉久久人人爽人人爽人人片av| 丰满少妇被猛烈进入高清播放| 国产薄丝脚交视频在线观看| 男女猛烈无遮挡免费视频app| 狠狠色狠狠色综合网| 亚洲精品久久久久久中文字幕| 天堂网www天堂在线资源| 中文字幕人妻第一区| 欧美性猛交aaaa片黑人| 色五月丁香五月综合五月4438| 麻豆ā片免费观看在线看| 欧美xxxx做受视频| 久久天天躁狠狠躁夜夜网站| 午夜在线a亚洲v天堂网2018| 久久无码精品一一区二区三区| 夜夜躁很很躁日日躁麻豆| 中文无码成人免费视频在线观看| 久久精品成人欧美大片| 人妻av无码专区| 色av综合av综合无码网站| 激情综合色五月六月婷婷| 欧美40老熟妇色xxxxx| 亚洲 小说区 图片区 都市| 精品国际久久久久999| 免费人成网站在线视频| 无码视频一区二区三区在线观看 | 亚洲国产av一区二区三区四区 | 日韩 欧美 国产 一区三|