在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DPF2 Antibody

  • 中文名稱:
    DPF2兔多克隆抗體
  • 貨號:
    CSB-PA007127GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    DPF2
  • 別名:
    Apoptosis response zinc finger protein antibody; BAF45D antibody; BRG1-associated factor 45D antibody; D4 antibody; D4 zinc and double PHD fingers family 2 antibody; Double PHD fingers 2 antibody; double PHD fingers family 2 antibody; DPF 2 antibody; DPF2 antibody; MGC10180 antibody; Protein requiem antibody; REQ antibody; REQU_HUMAN antibody; Requiem antibody; Requiem apoptosis response zinc finger antibody; UBI D4 antibody; ubi-d4 antibody; UBID 4 antibody; UBID4 antibody; zinc and double PHD fingers family 2 antibody; Zinc finger protein ubi d4 antibody; Zinc finger protein ubi-d4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human DPF2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays an active role in transcriptional regulation by binding modified histones H3 and H4. Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells. Might also have a role in the development and maturation of lymphoid cells. Involved in the regulation of non-canonical NF-kappa-B pathway.
  • 基因功能參考文獻:
    1. de novo variants in DPF2 cause Coffin-Siris syndrome and propose a dominant-negative mechanism of pathogenicity. PMID: 29429572
    2. Authors show that DPF2 interacts with the acetylated tails of both histones 3 and 4 via bipartite binding pockets on the DPF2 surface. Blocking these interactions through targeted mutagenesis of DPF2 abolishes its recruitment to target chromatin regions as well as its ability to prevent myeloid differentiation in vivo. PMID: 28533407
    3. Upon influenza virus infection, DPF2 dysregulated IFN-beta induction and expression of cytokines/chemokines and antiviral proteins. This study provides evidence that influenza virus utilizes DPF2 to escape host innate immunity. PMID: 28404846
    4. The demonstrate that the histone acetylation-binding double PHD finger (DPF) domains of human MOZ (also known as KAT6A) and DPF2 (also known as BAF45d) accommodate a wide range of histone lysine acylation with the strongest preference for propionylation (Kcr). PMID: 27775714
    5. the role of SMARCA4 and the two SWI/SNF subunits SMARCD2/BAF60B and DPF2/BAF45D in leukaemia, was investigated. PMID: 26571505
    6. DPF2 decreases monomeric and mono-ubiquitinated OCT4, assembles poly-ubiquitin chains on OCT4 mainly through Ub-K48 linkage PMID: 26417682
    7. crystal structure of the C2H2-type zinc finger domain of human DPF2 with a canonical C2H2 fold, which contains two beta strands and one alpha helix, was reported. PMID: 21888896
    8. found that targeting Requiem and Alg-2 did not result in extended culture viability, but resulted in an increase in maximum viable cell numbers and cumulative IVCD under fed-batch conditions PMID: 20571937

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    Requiem/DPF family
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 9964

    OMIM: 601671

    KEGG: hsa:5977

    STRING: 9606.ENSP00000436901

    UniGene: Hs.13495



主站蜘蛛池模板: 露脸叫床粗话东北少妇| 老司机久久一区二区三区| 成人av片在线观看免费| 色五月丁香六月欧美综合| 国产熟女一区二区三区四区五区| 又色又爽又高潮免费视频国产| 色丁狠狠桃花久久综合网| 亚洲v天堂v手机在线| 成人免费一区二区三区| 97夜夜澡人人爽人人喊a| 亚洲综合久久成人a片红豆| 国精产品一区一区三区免费视频| 伊人久久久精品区aaa片| 国产96在线 | 韩国| 午夜福利不卡片在线机免费视频 | 任你躁久久精品6| 亚洲国产欧美日韩在线人成| 色婷婷综合久久久中文字幕| 日本不卡三区| 午夜无码片在线观看影院y| 日韩吃奶摸下aa片免费观看| 久久天天躁狠狠躁夜夜网站| 仙踪林果冻传媒一区二区| 久久精品国产只有精品96| 日产精品久久久久久久性色| 青娱乐极品视觉盛宴国产视频 | 国产在线拍偷自揄拍无码| 国产在线乱码一区二区三区| 午夜色大片在线观看| 国产suv精品一区二区四| 日日av色欲香天天综合网| 亚洲精品午夜一区二区电影院| 夜夜高潮夜夜爽夜夜爱| 色屁屁www影院免费观看入口| 美女mm131午夜福利在线| 国产色无码精品视频免费| 性久久久久久| 国产在线欧美日韩精品一区| 久久精品人妻无码专区| 中文字幕无线码| 亚洲精品欧美综合一区二区 |