在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DOCK7 Antibody, HRP conjugated

DOCK7 Antibody, HRP conjugated

  • 中文名稱：
    DOCK7兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA836266LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DOCK7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DOCK7
  • 別名：
    DOCK7 antibody; KIAA1771Dedicator of cytokinesis protein 7 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization. As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton. Has a role in pigmentation. Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3.
  • 基因功能參考文獻：
    1. these results suggest that the DOCK-ANGPTL3 SNPs and their haplotypes were associated with the angiographic severity to coronary artery atherosclerosis and the risk of coronary artery disease (CAD) and ischemic stroke in the Southern Chinese Han population. PMID: 29454388
    2. Possible inter-locus interactions among the DOCK7, PCSK9 and GALNT2 SNPs were also noted. PMID: 26493351
    3. Differences in lipid profiles between the Jing and Han populations might partially attribute to the DOCK7, PCSK9 and GALNT2 gene polymorphisms and their haplotypes determining different risk for the development of cardiovascular diseases. PMID: 26744084
    4. Interaction of myosin VI and its binding partner DOCK7 plays an important role in NGF-stimulated protrusion formation in PC12 cells. PMID: 27018747
    5. These observations suggest that loss of DOCK7 function causes a syndromic form of epileptic encephalopathy by affecting multiple neuronal processes. PMID: 24814191
    6. Dock7 mediates serum- and HGF-induced glioblastoma cell invasion. PMID: 24518591
    7. DOCK7 functions as an essential and downstream regulator of RAGE-mediated cellular migration through the formation of dendritic pseudopodia. PMID: 23254359
    8. The action of DOCK7 in vivo may involve the coordinated integration of Cdc42/Rac signaling in the context of the membrane recruitment of a DOCK7 guanine nucleotide exchange factor (GEF) complex. PMID: 23718289
    9. Dock7 functions as an intracellular substrate for ErbB2 to promote Schwann cell migration. PMID: 18426980

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Epileptic encephalopathy, early infantile, 23 (EIEE23)
  • 亞細胞定位：
    Cell projection, axon. Note=Enriched in the developing axons of hippocampal neurons.
  • 蛋白家族：
    DOCK family
  • 組織特異性：
    Widely expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19190

    OMIM: 615730

    KEGG: hsa:85440

    STRING: 9606.ENSP00000340742

    UniGene: Hs.744927



主站蜘蛛池模板： 午夜私人成年影院| 3d动漫精品啪啪一区二区中| 最新国产aⅴ精品无码| 777yyy亚洲精品久久久| 人人妻人人妻人人人人妻人人| 女人高潮抽搐潮喷视频开腿| 午夜性刺激在线视频免费 | 中文字幕人成人乱码亚洲电影| 邻居少妇张开腿让我爽了在线观看| 无码日韩精品一区二区免费| 国产麻豆放荡av剧情演绎| 久久www成人_看片免费不卡| 精品玖玖玖视频在线观看| 欧美婷婷丁香五月社区| 国内少妇偷人精品视频| 女人被爽到呻吟gif动态图视看| 一区二区视频| 少妇白浆高潮无码免费区| 亚洲日韩片无码中文字幕| 亚洲桃色天堂网| 99亚洲乱人伦aⅴ精品| 毛多水多www偷窥小便| 7m精品福利视频导航| 日本少妇高潮喷水免费可以看| 在线 | 国产精品99传媒丿| а天堂中文最新一区二区三区| 女人被男人爽到呻吟的视频| 日韩精品无码一区二区| 人妻av无码系列专区移动可看| 亚洲成在人网站无码天堂| 无码av永久免费专区麻豆| 小说区 图片区色 综合区| 少妇下蹲露大唇无遮挡| 亚洲欧美国产双大乳头| 西欧free性满足hd| 中文字幕人妻无码一夲道| 色综合久久蜜芽国产精品| 久久人人爽人人爽人人片ⅴ| 国产乱子伦三级在线播放| 亚洲精品无码成人片久久| 亚洲跨种族黑人xxxxx|