在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DOCK7 Antibody, FITC conjugated

  • 中文名稱:
    DOCK7兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA836266LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DOCK7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DOCK7
  • 別名:
    DOCK7 antibody; KIAA1771Dedicator of cytokinesis protein 7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization. As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton. Has a role in pigmentation. Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3.
  • 基因功能參考文獻:
    1. these results suggest that the DOCK-ANGPTL3 SNPs and their haplotypes were associated with the angiographic severity to coronary artery atherosclerosis and the risk of coronary artery disease (CAD) and ischemic stroke in the Southern Chinese Han population. PMID: 29454388
    2. Possible inter-locus interactions among the DOCK7, PCSK9 and GALNT2 SNPs were also noted. PMID: 26493351
    3. Differences in lipid profiles between the Jing and Han populations might partially attribute to the DOCK7, PCSK9 and GALNT2 gene polymorphisms and their haplotypes determining different risk for the development of cardiovascular diseases. PMID: 26744084
    4. Interaction of myosin VI and its binding partner DOCK7 plays an important role in NGF-stimulated protrusion formation in PC12 cells. PMID: 27018747
    5. These observations suggest that loss of DOCK7 function causes a syndromic form of epileptic encephalopathy by affecting multiple neuronal processes. PMID: 24814191
    6. Dock7 mediates serum- and HGF-induced glioblastoma cell invasion. PMID: 24518591
    7. DOCK7 functions as an essential and downstream regulator of RAGE-mediated cellular migration through the formation of dendritic pseudopodia. PMID: 23254359
    8. The action of DOCK7 in vivo may involve the coordinated integration of Cdc42/Rac signaling in the context of the membrane recruitment of a DOCK7 guanine nucleotide exchange factor (GEF) complex. PMID: 23718289
    9. Dock7 functions as an intracellular substrate for ErbB2 to promote Schwann cell migration. PMID: 18426980

    顯示更多

    收起更多

  • 相關疾病:
    Epileptic encephalopathy, early infantile, 23 (EIEE23)
  • 亞細胞定位:
    Cell projection, axon. Note=Enriched in the developing axons of hippocampal neurons.
  • 蛋白家族:
    DOCK family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 19190

    OMIM: 615730

    KEGG: hsa:85440

    STRING: 9606.ENSP00000340742

    UniGene: Hs.744927



主站蜘蛛池模板: 丁香婷婷综合久久来来去| 中文字幕高清免费日韩视频在线| 亚州少妇无套内射激情视频| 18禁午夜宅男成年网站| 亚洲精品无码专区在线| 亚洲精品国产嫩草在线观看东京热| 黄网站色视频免费国产| 一本无码中文字幕在线观| 亚洲国产精久久久久久久| 乱熟女高潮一区二区在线| 成人欧美一区二区三区1314| 中文字幕三级人妻无码视频| 丰满人妻被公侵犯完整版| 国语自产拍无码精品视频在线| 亚洲日韩av无码| 日本亚洲色大成网站www久久| 人妻丰满熟妞av无码区| 一本丁香综合久久久久不卡网站| 亚洲欧美日韩中文播放| 亚洲成亚洲成网| 99精品国产一区二区三区不卡| 国产成人综合色就色综合| 亚洲天堂男人影院| 亚洲人成色777777精品音频| 亚洲国产精品无码中文字满| 国产片免费福利片永久| 又黄又爽的60分钟视频| 中日av乱码一区二区三区乱码| 国产精品无码av无码| 美女裸奶100%无遮挡免费网站| 国产成人av性色在线影院色戒 | 亚洲精品色情aⅴ色戒| 免费人成再在线观看视频| 成在人线无码aⅴ免费视频| 亚洲肥老太bbw中国熟女| 精品少妇人妻av免费久久久| 色伊人亚洲综合网站| 综合色一色综合久久网| 天天综合网天天综合色| 色哟哟网站在线观看| 无码三级av电影在线观看|