在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DNASE2 Antibody, Biotin conjugated

  • 中文名稱:
    DNASE2兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA007053LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DNASE2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DNASE2
  • 別名:
    Acid DNase antibody; Deoxyribonuclease 2 alpha antibody; Deoxyribonuclease 2 antibody; Deoxyribonuclease II alpha antibody; Deoxyribonuclease II antibody; Deoxyribonuclease II lysosomal antibody; Deoxyribonuclease-2-alpha antibody; Deoxyribonuclease2 antibody; DeoxyribonucleaseII antibody; DNASE 2 antibody; DNASE 2A antibody; DNase II alpha antibody; DNase II lysosomal antibody; DNASE2 antibody; DNASE2A antibody; DNaseII antibody; DNL 2 antibody; DNL antibody; DNL2 antibody; DNS2A_HUMAN antibody; Lysosomal DNase II antibody; R31240 2 antibody; R31240_2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Deoxyribonuclease-2-alpha protein (19-152AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
  • 基因功能參考文獻:
    1. Study identifies biallelic mutations in DNASE2, associated with a loss of DNase II endonuclease activity causing type I interferonopathy in three patients from two unrelated families. PMID: 29259162
    2. 15 nonsynonymous human DNase II SNPs were genotyped in three ethnic groups including 16 different populations using the PCR-restriction fragment length polymorphism technique. PMID: 24242851
    3. study demonstrated the relationship of genotypes/haplotypes with the in vivo DNase II and promoter activities; significant correlations between genotype in each rheumatoid arthritis (RA)-related SNP and enzymatic activity levels were found; alleles associated with RA exhibited a reduction in serum DNase II activity. PMID: 23019102
    4. upregulation of expression during myelomonocytic differentiation of HL-60 and THP-1 cells PMID: 12147225
    5. Sp1 and Sp3 are involved in up-regulation of this enzyme's transcriptoin during cell differentiation of hl-60 cells. PMID: 12694199
    6. the enzyme is a monomeric phospholipase D-family member with a pseudodimeric protein fold PMID: 17192590
    7. The association of SNPs in the 5'-regulatory region of the DNA degrading enzyme DNASE2 with Rheumatoid Arthritis implies a role for this enzyme in the pathogenesis of this autoimmune disease. PMID: 18812394

    顯示更多

    收起更多

  • 亞細胞定位:
    Lysosome.
  • 蛋白家族:
    DNase II family
  • 數據庫鏈接:

    HGNC: 2960

    OMIM: 126350

    KEGG: hsa:1777

    STRING: 9606.ENSP00000222219

    UniGene: Hs.118243



主站蜘蛛池模板: 噜噜色综合天天综合网mp3| 久精品国产欧美亚洲色aⅴ大片| 乱码视频午夜间在线观看| 国产一区二区三区免费高清在线播放 | 国产午夜成人无码免费| 亚洲精品久久久久一区二区| 国产麻豆一精品一av一免费 | 中文字幕人成乱码在线观看| 欧美色欧美亚洲另类二区| 啪啪激情婷婷久久婷婷色五月| 日本一卡二卡四卡无卡国产| 大乳丰满人妻中文字幕日本| 日本午夜免费啪视频在线| 成年女人午夜性视频| 内射合集对白在线| 五月丁香啪啪| 无码人妻精品一区二区三区不卡 | 国产一卡二卡三新区2022| 一区一区三区产品乱码| 国产不卡视频一区二区三区| 成人午夜无码专区性视频性视频| 在线 国产 精品 蜜芽| 长腿校花无力呻吟娇喘的视频| 国内精品久久久久伊人av| 亚洲人成自拍网站在线观看| 亚州日本乱码一区二区三区| 再深点灬舒服灬太大了网站| 人妻aⅴ中文字幕| 天堂久久天堂av色综合| 精品人伦一区二区三电影| 欧洲熟妇色xxxx欧美老妇| 欧美饥渴熟妇高潮喷水| 国产成人一区二区三区免费| 日韩av无码精品人妻系列| 2018年亚洲欧美在线v| 人妻丰满熟妇av无码区动漫| 99精品久久精品一区二区| 与子敌伦刺激对白播放的优点| 国产超碰人人做人人爱一二区视品| 男人j进女人p免费视频| 成人精品视频一区二区三区尤物|