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DNAJB8 Antibody, Biotin conjugated

  • 中文名稱:
    DNAJB8兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA836779LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DNAJB8 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DNAJB8
  • 別名:
    DJ6 antibody; DnaJ (Hsp40) homolog; subfamily B; member 8 antibody; DnaJ homolog subfamily B member 8 antibody; Dnajb8 antibody; DNJB8_HUMAN antibody; mDj6 antibody; MGC33884 antibody; OTTHUMP00000216243 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human DnaJ homolog subfamily B member 8 protein (1-232AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins.
  • 基因功能參考文獻:
    1. DNAJB8 is a central and versatile player in the protein aggregation and degradation system.DNAJB8 protein keeps Parkin C289G mutant protein in a soluble, degradation-competent form. PMID: 27713507
    2. Results show that DNAJB8 expression is induced by heat shock stress which increases side population cells and cancer stem-like cells. PMID: 29316077
    3. Taken together, the results indicate that DNAJB8 is expressed and has role in CRC CSC/CIC and that DNAJB8 is a novel target of CRC CSC/CIC-targeting immunotherapy. PMID: 24450541
    4. The mechanism of DNAJB6 and DNAJB8 is suppression of polyQ protein aggregation by directly binding the polyQ tract. PMID: 23612975
    5. Cancer stem-like cell (CSC) maintenance and that it offers a candidate for CSC-targeting immunotherapy in renal cell carcinoma PMID: 22552285
    6. DNAJB6b and DNAJB8 are superior suppressors of aggregation and toxicity of disease-associated polyglutamine proteins. PMID: 20159555

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  • 數據庫鏈接:

    HGNC: 23699

    OMIM: 611337

    KEGG: hsa:165721

    STRING: 9606.ENSP00000316053

    UniGene: Hs.518241



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