在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DNAJA1 Antibody

  • 中文名稱:
    DNAJA1兔多克隆抗體
  • 貨號:
    CSB-PA006999GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    DJ 2 antibody; DJ2 antibody; DjA1 antibody; DnaJ (Hsp40) homolog; subfamily A; member 1 antibody; DnaJ homolog subfamily A member 1 antibody; DnaJ protein homolog 2 antibody; DNAJ2 antibody; Dnaja1 antibody; DNJA1_HUMAN antibody; hDJ 2 antibody; HDJ-2 antibody; HDJ2 antibody; Heat shock 40 kDa protein 4 antibody; heat shock protein DNAJ like 2 antibody; Heat shock protein J2 antibody; HSDJ antibody; HSJ-2 antibody; HSJ2 antibody; HSPF4 antibody; Human DnaJ protein 2 antibody; NEDD7 antibody; Neural precursor cell expressed developmentally down regulated 7 antibody; OTTHUMP00000021193 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human DNAJA1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Co-chaperone for HSPA8/Hsc70. Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV.
  • 基因功能參考文獻:
    1. that DNAJA1 controls the fate of misfolded stabilization of mutant p53 PMID: 27775703
    2. Therefore, we propose that DnaJA1 is co-opted by the influenza A virus to enter the nucleus and to enhance its RNA polymerase activity in an Hsp70 cochaperone-independent manner. PMID: 25253355
    3. structure and function of human DNAJA1 and its relationship to pancreatic cancer PMID: 24512202
    4. we combined the Hsp70-NEF pairs with cochaperones of the J protein family (DnaJA1, DnaJA2, DnaJB1, and DnaJB4) to generate 16 permutations. PMID: 24318877
    5. Moreover, the levels of DnaJA1 and Hsp70 seem to play against each other with regard to tau: as DnaJA1 levels increase, tau levels are reduced, but this can be prevented if Hsp70 levels are simultaneously induced. PMID: 22343013
    6. Hdj2 directly associates with Japanese encephalitis virus nonstructural protein NS5 and facilitates viral replication. PMID: 21999493
    7. Hsc70 and a dimer of DjA1 independently bind to an unfolded protein PMID: 20363747
    8. Hsp40 type 1 chaperones DJA1 (DNAJA1/Hdj2) and DJA2 (DNAJA2) as key modulators of hERG degradation PMID: 19940115
    9. Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy PMID: 11796717
    10. HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor PMID: 11809754
    11. sequence analysis of two isoforms PMID: 12974469
    12. Multiple tissue polymerase chain reaction (PCR) results showed that nDnaJA1 expressed highly in testis and lung but low in thymus, prostate, colon and liver PMID: 15595953
    13. Results indicate that DjA1 and DjB4 of subfamilies A and B of human Hsp40 have different quaternary structures and chaperone functions. PMID: 15661747
    14. DJA1 was inhibitory of refolding with DJA2 and Hsc70. PMID: 18684711

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Membrane; Lipid-anchor. Cytoplasm. Microsome. Nucleus. Cytoplasm, perinuclear region. Mitochondrion.
  • 組織特異性:
    Ubiquitous. Isoform 2 is highly expressed in testis and lung, but detected at low levels in thymus, prostate, colon and liver.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 5229

    OMIM: 602837

    KEGG: hsa:3301

    STRING: 9606.ENSP00000369127

    UniGene: Hs.445203



主站蜘蛛池模板: 女上男下啪啪激烈高潮无遮盖| 色妞精品av一区二区三区| 美女被张开双腿日出白浆| 骚虎成人免费99xx| 一道本在线伊人蕉无码| 风韵丰满熟妇啪啪区老熟熟女| 亚洲欧美在线人成最新| 欧美中文亚洲v在线| 中文字幕久热精品视频在线| 大又大粗又爽又黄少妇毛片| 与子敌伦刺激对白播放的优点 | 亚洲伊人久久大香线蕉av| 好爽…又高潮了毛片免费看| 国产乱子伦农村叉叉叉| 娜娜麻豆国产电影| 人妻av无码专区| 波多野结衣av手机在线观看 | 久久青草费线频观看| 天天躁日日躁狠狠躁2018| 让少妇高潮无乱码高清在线观看| 男女啪啪进出阳道猛进| 国产成a人片在线观看视频下载| 亚洲va久久久噜噜噜久久男同| 92精品成人国产在线观看| 亚洲成av人片在www色猫咪| 免费观看激色视频网站| 国产丝袜在线精品丝袜| 乱码国产丰满人妻www| 粉嫩少妇内射浓精videos| 国产清纯白嫩初高生在线观看| 亚洲国产成人久久综合碰碰| 亚洲精品无amm毛片| 一本一道色欲综合网中文字幕| 日韩加勒比一本无码精品| 欧美另类人妖| 熟女人妻一区二区三区免费看| 国产在热线精品视频99公交| 无码免费h成年动漫在线观看| 久久丫精品久久丫| 国产影片av级毛片特别刺激| 人妻av无码系列一区二区三区 |