在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DNAJA1 Antibody, Biotin conjugated

  • 中文名稱:
    DNAJA1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA006999LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DNAJA1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    DJ 2 antibody; DJ2 antibody; DjA1 antibody; DnaJ (Hsp40) homolog; subfamily A; member 1 antibody; DnaJ homolog subfamily A member 1 antibody; DnaJ protein homolog 2 antibody; DNAJ2 antibody; Dnaja1 antibody; DNJA1_HUMAN antibody; hDJ 2 antibody; HDJ-2 antibody; HDJ2 antibody; Heat shock 40 kDa protein 4 antibody; heat shock protein DNAJ like 2 antibody; Heat shock protein J2 antibody; HSDJ antibody; HSJ-2 antibody; HSJ2 antibody; HSPF4 antibody; Human DnaJ protein 2 antibody; NEDD7 antibody; Neural precursor cell expressed developmentally down regulated 7 antibody; OTTHUMP00000021193 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human DnaJ homolog subfamily A member 1 protein (8-106AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Co-chaperone for HSPA8/Hsc70. Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV.
  • 基因功能參考文獻:
    1. that DNAJA1 controls the fate of misfolded stabilization of mutant p53 PMID: 27775703
    2. Therefore, we propose that DnaJA1 is co-opted by the influenza A virus to enter the nucleus and to enhance its RNA polymerase activity in an Hsp70 cochaperone-independent manner. PMID: 25253355
    3. structure and function of human DNAJA1 and its relationship to pancreatic cancer PMID: 24512202
    4. we combined the Hsp70-NEF pairs with cochaperones of the J protein family (DnaJA1, DnaJA2, DnaJB1, and DnaJB4) to generate 16 permutations. PMID: 24318877
    5. Moreover, the levels of DnaJA1 and Hsp70 seem to play against each other with regard to tau: as DnaJA1 levels increase, tau levels are reduced, but this can be prevented if Hsp70 levels are simultaneously induced. PMID: 22343013
    6. Hdj2 directly associates with Japanese encephalitis virus nonstructural protein NS5 and facilitates viral replication. PMID: 21999493
    7. Hsc70 and a dimer of DjA1 independently bind to an unfolded protein PMID: 20363747
    8. Hsp40 type 1 chaperones DJA1 (DNAJA1/Hdj2) and DJA2 (DNAJA2) as key modulators of hERG degradation PMID: 19940115
    9. Mammalian, yeast, bacterial, and chemical chaperones reduce aggregate formation and death in a cell model of oculopharyngeal muscular dystrophy PMID: 11796717
    10. HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor PMID: 11809754
    11. sequence analysis of two isoforms PMID: 12974469
    12. Multiple tissue polymerase chain reaction (PCR) results showed that nDnaJA1 expressed highly in testis and lung but low in thymus, prostate, colon and liver PMID: 15595953
    13. Results indicate that DjA1 and DjB4 of subfamilies A and B of human Hsp40 have different quaternary structures and chaperone functions. PMID: 15661747
    14. DJA1 was inhibitory of refolding with DJA2 and Hsc70. PMID: 18684711

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Lipid-anchor. Cytoplasm. Microsome. Nucleus. Cytoplasm, perinuclear region. Mitochondrion.
  • 組織特異性:
    Ubiquitous. Isoform 2 is highly expressed in testis and lung, but detected at low levels in thymus, prostate, colon and liver.
  • 數據庫鏈接:

    HGNC: 5229

    OMIM: 602837

    KEGG: hsa:3301

    STRING: 9606.ENSP00000369127

    UniGene: Hs.445203



主站蜘蛛池模板: 欧美不卡视频一区发布| 国产精品白浆在线观看免费| 亚洲精品国产品国语在线观看| 久久精品女人的天堂av| 亚洲色欲在线播放一区| 亚洲精品久久婷婷丁香51| 免费ā片在线观看| 日韩中文高清在线专区| 狠狠躁夜夜躁人人爽天天bl| 无码精品国产va在线观看| 国产成人精品亚洲线观看| 国产又粗又猛又大爽老大爷| 精品少妇人妻av久久久| 精品视频在线观自拍自拍| 久久不见久久见免费影院www| 国产一区二区在线视频| 国产欧美在线一区二区三| 国产乱码一区二区三区爽爽爽| 影音先锋中文字幕人妻| 亚洲性无码av在线欣赏网| 天堂最新版资源网| 亚洲伊人久久精品酒店| 亚洲日韩欧洲乱码av夜夜摸| 无遮挡aaaaa大片免费看 | 久久国产高潮流白浆免费观看| 国产成人a视频高清在线观看| 国产成人精品福利网站| 国产成人av区一区二区三| 国产精品午夜小视频观看| 日韩成人无码中文字幕| 国产精品多p对白交换绿帽| 色天使亚洲综合一区二区| av天堂午夜精品蜜臀av| 成 人片 黄 色 大 片| 欧美牲交a欧美牲交aⅴ图片| 亚洲精品成人久久电影网 | 99久久国语露脸精品国产| 日本久久久久久久久久加勒比| 波多野结衣办公室33分钟| 日韩视频在线观看| 男人猛戳女人30分钟视频大全|