在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DNAH5 Antibody, FITC conjugated

  • 中文名稱:
    DNAH5兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA819476LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DNAH5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DNAH5
  • 別名:
    axonemal antibody; Axonemal beta dynein heavy chain 5 antibody; Ciliary dynein heavy chain 5 antibody; DNAH 5 antibody; Dnah5 antibody; DNAHC5 antibody; DYH5_HUMAN antibody; Dynein heavy chain 5 antibody; Dynein heavy chain 5; axonemal antibody; HL1 antibody; KIAA1603 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Dynein heavy chain 5, axonemal protein (2364-2560AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles.
  • 基因功能參考文獻:
    1. A novel mutation causing primary ciliary dyskinesia was found in Japanese patients. PMID: 28939216
    2. to the best of our knowledge, the first reported case of PCD caused by the DNAH5 mutation in a Japanese patient. PMID: 27779714
    3. These findings demonstrated that new DNAH5 mutations could be used for molecular diagnosis of Kartagener syndrome, providing families with genetic counseling and prenatal diagnosis. PMID: 27988889
    4. The mutation of p.Glu2610Gly in DNAH5 is novel. PMID: 24912412
    5. In chronic obstructive pulmonary disease, total lung capacity was associated with a SNP in DNAH5. PMID: 25134640
    6. A novel mutation in DNAH5 (c. 8030G>A) is identified in a Han Chinese family with chronic rhinosinusitis and primary ciliary dyskinesia. PMID: 24150548
    7. DNAH5 (rs2277046) is associated with single nucleotide polymorphisms in Korean patients, either non-segmental or segmental type. PMID: 23678272
    8. DNAH5 is the cause of primary ciliary dyskinesia in two siblings in a nuclear family as identified by whole genome sequencing. PMID: 20220176
    9. immunofluorescence studies of respiratory epithelial cells with secondary ciliary dyskinesia identified in vitro and in vivo normal axonemal DNAH5 localization PMID: 16492982
    10. DNAH5 is frequently mutated in patients with primary ciliary dyskinesia exhibiting outer dynein arm defects and mutations cluster in five exons. PMID: 16627867
    11. Male carriers of the mutations always exhibit asthenozoospermia, whereas female carriers manifest no alterations in either fertility or pulmonary clearance. PMID: 18492703
    12. Two dynein genes, encoding ODA intermediate chain (DNAI1) and heavy chain (DNAH5), have been seen to be mutated in approximately 30-38% of the families PMID: 19300264
    13. Although genetic alterations remain to be identified in most patients, DNAH5 is to date the main PCD gene. PMID: 19357118
    14. Two "major" genes, DNAI1 and DNAH5, underlie PCD in nearly half of the patients with ODA defects PMID: 19410201

    顯示更多

    收起更多

  • 相關疾病:
    Ciliary dyskinesia, primary, 3 (CILD3)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton, cilium axoneme.
  • 蛋白家族:
    Dynein heavy chain family
  • 組織特異性:
    Expressed in airway epithelial cells (at protein level). Not detected in spermatozoa (at protein level).
  • 數據庫鏈接:

    HGNC: 2950

    OMIM: 603335

    KEGG: hsa:1767

    STRING: 9606.ENSP00000265104

    UniGene: Hs.212360



主站蜘蛛池模板: 婷婷六月丁香缴 清| 精品国产三级在线观看| 久久九九av免费精品| 免费无人区男男码卡二卡| 欧美日韩国产中文高清视频 | 狠狠久久噜噜熟女| 无码中文字幕波多野结衣| 国产成人综合久久免费| 人妻夜夜添夜夜无码av| 久久亚洲私人国产精品va| 国产漂亮白嫩美女在线观看| 无码帝国www无码专区色综合| 亚洲成a人无码| 精品国产乱码久久久久久影片 | 免费看又黄又无码的网站| 国产 一二三四五六| 在线偷着国产精选视频| 男人把女人桶到爽免费应用| 国产亚洲精品精华液| 欧洲美熟女乱又伦av影片| 日本免费更新一二三区不卡 | 老湿机69福利区无码| 中文人妻熟妇乱又伦精品| 在线天堂中文官网| 99热精品久久只有精品| 国产精品成人永久在线四虎| 免费看国产成年无码av| 久碰人妻人妻人妻人妻人掠| 国产精品久久久久久久久人妻 | 国产交换配乱婬视频| 熟妇丰满多毛的大隂户| 青草精品国产福利在线视频| 精品久久久久中文字幕app| 免费三级网站| 国产亚洲精品a在线| 欧美乱人伦视频在线| 三上悠亚久久精品| 成人免费看黄网站yyy456| 激情综合婷婷丁香五月情 | 亚洲精品久久久久国产| 日本老熟妇毛茸茸|