在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DNAH5 Antibody, Biotin conjugated

DNAH5 Antibody, Biotin conjugated

  • 中文名稱：
    DNAH5兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA819476LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DNAH5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DNAH5
  • 別名：
    axonemal antibody; Axonemal beta dynein heavy chain 5 antibody; Ciliary dynein heavy chain 5 antibody; DNAH 5 antibody; Dnah5 antibody; DNAHC5 antibody; DYH5_HUMAN antibody; Dynein heavy chain 5 antibody; Dynein heavy chain 5; axonemal antibody; HL1 antibody; KIAA1603 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Dynein heavy chain 5, axonemal protein (2364-2560AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles.
  • 基因功能參考文獻(xiàn)：
    1. A novel mutation causing primary ciliary dyskinesia was found in Japanese patients. PMID: 28939216
    2. to the best of our knowledge, the first reported case of PCD caused by the DNAH5 mutation in a Japanese patient. PMID: 27779714
    3. These findings demonstrated that new DNAH5 mutations could be used for molecular diagnosis of Kartagener syndrome, providing families with genetic counseling and prenatal diagnosis. PMID: 27988889
    4. The mutation of p.Glu2610Gly in DNAH5 is novel. PMID: 24912412
    5. In chronic obstructive pulmonary disease, total lung capacity was associated with a SNP in DNAH5. PMID: 25134640
    6. A novel mutation in DNAH5 (c. 8030G>A) is identified in a Han Chinese family with chronic rhinosinusitis and primary ciliary dyskinesia. PMID: 24150548
    7. DNAH5 (rs2277046) is associated with single nucleotide polymorphisms in Korean patients, either non-segmental or segmental type. PMID: 23678272
    8. DNAH5 is the cause of primary ciliary dyskinesia in two siblings in a nuclear family as identified by whole genome sequencing. PMID: 20220176
    9. immunofluorescence studies of respiratory epithelial cells with secondary ciliary dyskinesia identified in vitro and in vivo normal axonemal DNAH5 localization PMID: 16492982
    10. DNAH5 is frequently mutated in patients with primary ciliary dyskinesia exhibiting outer dynein arm defects and mutations cluster in five exons. PMID: 16627867
    11. Male carriers of the mutations always exhibit asthenozoospermia, whereas female carriers manifest no alterations in either fertility or pulmonary clearance. PMID: 18492703
    12. Two dynein genes, encoding ODA intermediate chain (DNAI1) and heavy chain (DNAH5), have been seen to be mutated in approximately 30-38% of the families PMID: 19300264
    13. Although genetic alterations remain to be identified in most patients, DNAH5 is to date the main PCD gene. PMID: 19357118
    14. Two "major" genes, DNAI1 and DNAH5, underlie PCD in nearly half of the patients with ODA defects PMID: 19410201

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Ciliary dyskinesia, primary, 3 (CILD3)
  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton, cilium axoneme.
  • 蛋白家族：
    Dynein heavy chain family
  • 組織特異性：
    Expressed in airway epithelial cells (at protein level). Not detected in spermatozoa (at protein level).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2950

    OMIM: 603335

    KEGG: hsa:1767

    STRING: 9606.ENSP00000265104

    UniGene: Hs.212360



主站蜘蛛池模板： 熟睡人妻被讨厌的公侵犯深田咏美| 国产精品色无码av在线观看 | 成人亚洲欧美成αⅴ人在线观看 | 国产无遮挡aaa片爽爽| 10000部拍拍拍免费视频| 99在线精品免费视频九九视| 精品麻豆丝袜高跟鞋av| 无码ol丝袜高跟秘书在线观看| 国产百合互慰吃奶互揉视频| 377p欧洲日本亚洲大胆| 丰满女人又爽又紧又丰满| 国产精品 无码专区| 亚洲精品无码一二区a片| 日本一区二区无卡高清视频| 黑人大战日本人妻嗷嗷叫不卡视频 | 久久婷婷丁香七月色综合| 亚洲另类欧美在线电影| 亚洲国产香蕉碰碰人人| 少妇白浆高潮无码免费区| 国产乱子伦精品免费视频| 国产精品午夜福利麻豆| 在线观看国产精品乱码app| 久久精品成人亚洲另类欧美 | 亚洲一区在线日韩在线尤物| 99精品国产综合久久久久五月天| 99re8这里有精品热视频免费| 成人欧美一区二区三区在线| 四虎影视无码永久免费| 中文字幕av无码免费一区| 伊人久久大香线蕉无码| 国产成人无码av在线播放dvd| 免费又黄又裸乳的视频| 亚洲成片在线观看12345| 在线 | 国产精品星空传媒丿| 中文字幕丰满孑伦无码专区| 性xxxx欧美老妇胖老太269| 日本人又黄又爽又色的视频| 8x国产精品视频| 一本一道波多野结衣av一区| 亚洲va中文字幕无码久久 | 少妇性bbb搡bbb爽爽爽欧美|