在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DNAH1 Antibody, FITC conjugated

  • 中文名稱:
    DNAH1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA878961LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DNAH1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    DNAH1 antibody; DHC7 antibody; DNAHC1 antibody; KIAA1410 antibody; Dynein heavy chain 1 antibody; axonemal antibody; Axonemal beta dynein heavy chain 1 antibody; Ciliary dynein heavy chain 1 antibody; Heat shock regulated protein 1 antibody; HSRF-1 antibody; hDHC7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Dynein heavy chain 1, axonemal protein (2225-2407AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme.
  • 基因功能參考文獻:
    1. DNAH1 variations were identified in 6 of 287 patients, including 8 heterozygous variations in exons and a splicing site. 4 variations (g.52400764G>C, g.52409336C>T, g.52430999_52431000del, g.52412624C>A) had already been registered in the 1000 Genomes and Exome Aggregation Consortium databases. The other novel variations (g.52418050del, g.52404762T>G, g.52430536del, g.52412620del) were all predicted to be pathogenic. PMID: 30544445
    2. Pedigree analysis supported the notion that the combination of DNAH1 gene mutations 52430998CCT>C and 52409336C>T and 52428484G>T alone were associated with MMAF. CONCLUSION(S): These DNAH1 gene mutations may be associated with DFS and infertility in the Han population. PMID: 28577616
    3. This mutation was distinct from previously reported DNAH1 mutations associated with MMAF and only affected the East Asian group. Furthermore, the variant DNAH1 protein could not be detected in spermatozoa by Western blot or immunofluorescence staining although DNAH1 mRNA was expressed in the spermatozoa. PMID: 27573432
    4. variation in DNAH1 may play a role in primary ciliary dyskinesia PMID: 25927852
    5. Although DNAH1 is expressed in other ciliated cells, infertility was the only symptom of primary ciliary dyskinesia observed in affected subjects, suggesting that DNAH1 function in cilium is not as critical as in sperm flagellum. PMID: 24360805
    6. Male carriers of the mutations always exhibit asthenozoospermia, whereas female carriers manifest no alterations in either fertility or pulmonary clearance. PMID: 18492703
    7. Dynein motor function is important for regulating Gag and viral RNA egress on endosomal membranes in the cytoplasm to directly impact on viral production. PMID: 19286658
    8. clathrin serving as a regulator of SNX4-dependent transport; upon clathrin release, dynein may bind SNX4 and mediate retrograde movement PMID: 19529763

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Spermatogenic failure 18 (SPGF18); Ciliary dyskinesia, primary, 37 (CILD37)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.
  • 蛋白家族:
    Dynein heavy chain family
  • 組織特異性:
    Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in brain.
  • 數據庫鏈接:

    HGNC: 2940

    OMIM: 603332

    KEGG: hsa:25981

    STRING: 9606.ENSP00000401514

    UniGene: Hs.655469



主站蜘蛛池模板: 久久国内精品自在自线400部| 精品国产一二三产品区别在哪| 久久视频这里只精品| 精品国产av一区二区果冻传媒 | 久久99精品国产免费观观| 亚洲精品久久| 欧妇女乱妇女乱视频| 久久夜色撩人精品国产小说| 免费人成黄页在线观看国产| 国产成人久久综合第一区| 熟女人妻aⅴ一区二区三区60路| 欧美亚洲色综久久精品国产| 国产精品久久久久av| 亚洲国产精品无码7777一线| 亚州久久久久区1区2少妇| 国产亚洲视频中文字幕97精品| 免费观看性行为视频的网站| 久久人人97超碰超国产| 国产精品综合av一区二区国产馆| 亚洲 欧美 日韩 国产综合 在线| 欧美黑人欧美精品刺激| 国产乱人伦偷精品视频下| 久久99九九精品久久久久蜜桃| 午夜精品久久久久久毛片| 亚洲va久久久噜噜噜久久天堂| 曰批免费视频播放免费直播| 久久天天躁狠狠躁夜夜96流白浆 | 一本无码久本草在线中文字幕dvd| 亚洲人成色777777精品音频| 免费国产黄网在线观看| 国产精品乱码久久久久软件| 欧洲成人午夜精品无码区久久| 无遮无挡爽爽免费毛片| 骚女人干起来舒服视频在线 | 12裸体自慰免费观看网站| 337p日本欧洲亚洲大胆精筑 | 国内露脸中年夫妇交换| 国产a三级久久精品| 国产日韩在线视看高清视频手机| 少妇人妻无码专区视频| 色 亚洲 日韩 国产 综合|