在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DLEC1 Antibody

  • 中文名稱:
    DLEC1兔多克隆抗體
  • 貨號:
    CSB-PA080103
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    DLEC1
  • 別名:
    DLEC1 antibody; DLC1Deleted in lung and esophageal cancer protein 1 antibody; Deleted in lung cancer protein 1 antibody; DLC-1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human DLEC1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    IHC, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Essential for spermatogenesis and male fertility. May play an important role in sperm head and tail formation. May act as a tumor suppressor by inhibiting cell proliferation.
  • 基因功能參考文獻:
    1. We found no correlation between the DLEC1, TUSC4 and MLH1 gene expression and NSCLC patient characteristics (gender, age and smoking) or cancer histopathology. No significant differences in the gene expression among NSCLC subtypes indicate the weakness of DLEC1, TUSC4 and MLH1 expression analysis as potential differentiating markers of NSCLC subtypes in the Polish population. PMID: 28674222
    2. the expression levels of DLEC1 and ITGA9 were prominently decreased in lung tumor samples PMID: 27287342
    3. DLEC1 mediates tumor-suppressive activities through NF-kappaB signaling. PMID: 25648635
    4. DLEC1 methylation was not associated with the clinicopathological variables of gastric cancer. PMID: 25574068
    5. DLEC1 is down-regulated in head and neck squamous cell tumors and it's promoter methylation is not associated with the clinicopathological parameters. PMID: 25746324
    6. methylation-mediated silencing of DLEC1 plays an important role in multiple lymphomagenesis, and may serve as a non-invasive tumor marker for lymphoma diagnosis PMID: 23050586
    7. Repression of DLEC1 in squamous cell carcinoma tissues is associated with promoter hypermethylation. DLEC1 is downregulated in sinonasal squamous cell carcinoma and inverted papilloma and has a distinct mechanism. PMID: 22569009
    8. Epigenetic inactivation of DLEC1 was crucial in gastric and colorectal carcinogenesis. DLEC1 methylation in serum may be a promise biomarker for GAC and CRAC early diagnosis. PMID: 21443130
    9. results demonstrate that down-expression and promoter methylation of DLEC1 increased from normal tissues to premalignancies and then to malignancies. PMID: 20952247
    10. Frequent epigenetic inactivation of deleted in lung and esophageal cancer 1 gene by promoter methylation is associated with non-small-cell lung cancer. PMID: 20630829
    11. DLEC1 is often down-regulated by CpG methylation and shows tumor inhibitory function in renal cell carcinoma cells, indicating its role as a tumor suppressor PMID: 20639048
    12. DLEC1 expression levels were significantly lower in samples from patients who developed metastasis, local recurrence, or died of breast cancer when compared to those who were disease free for >10 years. PMID: 20530412
    13. DLEC1 suppresses the growth of ovarian cancer cells and its downregulation is closely associated with promoter hypermethylation and histone hypoacetylation PMID: 16756719
    14. Silencing of DLEC1 expression by promoter hypermethylation and histone deacetylation may be important in nasopharyngeal carcinoma tumorigenesis. PMID: 17099870
    15. DLEC1 is a candidate tumor suppressor gene that plays an important role in the development and progression of hepatocellular carcinoma. PMID: 18191269
    16. DLEC1 methylation was an independent marker of poor survival in patients with non-small cell lung carcinoma. PMID: 18594535
    17. DLEC1 underwent promoter methylation-associated silencing in colon and gastric tumour cell lines and primary tumours. PMID: 19156137

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Lung cancer (LNCR); Esophageal cancer (ESCR)
  • 亞細胞定位:
    Cytoplasm.
  • 組織特異性:
    Expressed in all tissues examined. Expression is highest in prostate and testis.
  • 數據庫鏈接:

    HGNC: 2899

    OMIM: 133239

    KEGG: hsa:9940

    STRING: 9606.ENSP00000308597

    UniGene: Hs.714499



主站蜘蛛池模板: 欧美 日产 国产在线观看| 国产免费久久精品99久久| 女人被弄到高潮的免费视频| 亚洲人成人伊人成综合网无码| 久青青在线观看视频国产| 久久久久99精品成人片试看| 久久国产色av免费看| 亚洲另类成人小说综合网| 中文日产幕无线码6区收藏| 岛国av动作片在线观看| 漂亮人妻去按摩被按中出| 亚洲 丝袜 制服 欧美 另类| 日本大片免费观看视频| 中文字幕精品久久久久人妻| 亚洲日韩va无码中文字幕| 亚洲精品夜夜夜妓女网| 亚洲伊人久久成人综合网| 国产精品久久久久无码av色戒| 香蕉久久久久久久av网站| 日本欧美一区二区三区在线播放| 欧美亚洲高清国产| 久久精品国产99国产精品澳门| 7878成人国产在线观看| 国内精品久久久久影院优| 午夜亚洲福利在线老司机| 亚洲精品动漫免费二区| 国产精品一区二区在线蜜芽tv| 亚洲人成无码网www| 精品无码无人网站免费视频| 2019最新久久久视频精品| 成人无码午夜在线观看| 亚洲熟妇无码av| 成人h动漫精品一区二区| 亚洲爆乳成av人在线蜜芽| 欧洲无码一区二区三区在线观看| 国产精品亚洲专区无码牛牛| 亚洲 欧美 另类 制服 日韩| 丰满多毛少妇做爰视频爽爽和| 欧美最猛黑人xxxx| 色一情一乱一伦一区二区三区小说 | 日本一道一区二区视频|