DIAPH2 Antibody
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中文名稱：DIAPH2兔多克隆抗體
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貨號：CSB-PA006891ESR1HU
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規格：￥440
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圖片：
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Western blot
All lanes: DIAPH2 antibody at 4.75μg/ml
Lane 1: 293T whole cell lysate
Lane 2: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 126, 125 kDa
Observed band size: 126 kDa -
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA006891ESR1HU at dilution of 1:100 -
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA006891ESR1HU at dilution of 1:100
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) DIAPH2 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：Dia 2 antibody; DIA antibody; Dia drome antibody; Dia2 antibody; Diap 2 antibody; Diap2 antibody; DIAP2_HUMAN antibody; DIAPH 2 antibody; Diaph2 antibody; Diaphanous 2 antibody; Diaphanous homolog 2 (Drosophila) antibody; Diaphanous homolog 2 antibody; Diaphanous related formin 2 antibody; Diaphanous-related formin-2 antibody; Diaphanous2 antibody; Diaphorase 2 antibody; Diaphorase2 antibody; DRF 2 antibody; DRF2 antibody; FLJ11167 antibody; OTTHUMP00000024270 antibody; OTTHUMP00000024271 antibody; OTTHUMP00000062171 antibody; POF 2 antibody; POF antibody; POF2 antibody; Protein diaphanous homolog 2 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Protein diaphanous homolog 2 protein (1-120AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton.
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基因功能參考文獻：
- Low DIA2 expression is associated with breast cancer. PMID: 29596520
- DIAPH2 has been associated with premature ovarian insufficiency, an aging phenotype in humans. PMID: 24037343
- In podocytes, INF2 appears to be an important modulator of actin-dependent behaviors that are under the control of Rho/mDia signaling. PMID: 23620398
- Dia2 and DIP co-tether to nascent blebs and this linkage is required for bleb formation. PMID: 23024796
- Long HIV filopodial formation in infected dendritic cells was dependent on the formin diaphanous 2 (Diaph2) PMID: 22685410
- Our results indicated that DIAPH2 may be a polygenic pleiotropy for premature ovarian failure (POF) and AMD. PMID: 21386871
- Dia2 plays an important role in formation of lamellipodia. PMID: 18044991
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相關疾病：Premature ovarian failure 2A (POF2A)
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亞細胞定位：[Isoform 3]: Cytoplasm, cytosol. Early endosome. Note=Isoform 3 is cytosolic but when coexpressed with RHOD, the 2 proteins colocalize to early endosomes.
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蛋白家族：Formin homology family, Diaphanous subfamily
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組織特異性：Expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes.
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數據庫鏈接：
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