在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DEF6 Antibody

DEF6 Antibody

  • 中文名稱：
    DEF6兔多克隆抗體
  • 貨號：
    CSB-PA884467LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Mouse liver tissue, Mouse kidney tissue
      All lanes: DEF6 antibody at 4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 74 kDa
      Observed band size: 74 kDa
    • Immunofluorescent analysis of U251 cells using CSB-PA884467LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DEF6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DEF6
  • 別名：
    DEF-6 antibody; Def6 antibody; DEFI6_HUMAN antibody; Differentially expressed in FDCP 6 homolog antibody; Differentially expressed in FDCP 6 homologue mouse antibody; IBP antibody; IRF4-binding protein antibody; Swap70 like adapter of T cells antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Differentially expressed in FDCP 6 homolog protein (20-114AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，DEF6 Antibody (CSB-PA884467LA01HU)，的標記方式是Non-conjugated。對于DEF6 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA884467LB01HU DEF6 Antibody, HRP conjugated ELISA
    FITC CSB-PA884467LC01HU DEF6 Antibody, FITC conjugated
    Biotin CSB-PA884467LD01HU DEF6 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling.
  • 基因功能參考文獻：
    1. this study identifies Def6 as a novel inhibitor of osteoclastogenesis in physiological and inflammatory conditions PMID: 28314855
    2. DEF6 expression may serve as an independent prognostic factor, and interacted positively with p16 toward high tumor stage and shorter survival. PMID: 27488395
    3. IBP was expressed ectopically in someoral squamous cell carcinoma samples and correlated significantly with tumor size, differentiation, clinical stage and distant metastases PMID: 23088770
    4. DEF6, a novel substrate for the Tec kinase ITK, contains a glutamine-rich aggregation-prone region and forms cytoplasmic granules that co-localize with P-bodies. PMID: 22829599
    5. Molecular cloning of IBP, a guanine nucleotide exchange factor, which is highly expressed in the immune system. PMID: 12651066
    6. IBP is a novel guanine nucleotide exchange factor and is recruited to the immunological synapse by T cell receptor engagement PMID: 12923183
    7. DEF6 not only activates Rho-family GTPases but also cooperates with activated Rac1 to exert its cellular function PMID: 17121847
    8. level of expression correlates with the degree of malignancy in breast carcinoma tissues PMID: 19393345
    9. Overexpression of the Interferon regulatory factor 4-binding protein is associated with Colorectal Carcinoma. PMID: 19679060
    10. DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA. PMID: 15023524

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane. Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, filopodium.
  • 組織特異性：
    Broadly expressed in the immune system and can be detected in T and B-cells.
  • 數據庫鏈接：

    HGNC: 2760

    OMIM: 610094

    KEGG: hsa:50619

    STRING: 9606.ENSP00000319831

    UniGene: Hs.15476



主站蜘蛛池模板： 欧美s码亚洲码精品m码| 免费观看男女性高视频| 色诱久久久久综合网ywww| 久久天天躁夜夜躁狠狠躁| 国产精品无码av一区二区三区| 18禁止看的免费污网站| 99精品久久久久久久婷婷| 久久综合一色综合久久小蛇| 国产福利姬喷水福利在线观看| 国产精品va无码二区| 精品国模一区二区三区| 久久免费的精品国产v∧| 国产av激情无码久久| av无码人妻一区二区三区牛牛| 国内精品久久久久影院优| 亚洲久久久久久中文字幕| 亚洲国产中文在线二区三区免| 国产高清av在线播放| 九色精品国产成人综合网站| 国产精品区一区二区三在线播放| 日本va在线视频播放| 久久99精品久久久久久动态图| 无码国产精品一区二区免费vr| 亚洲中文无码av永久伊人| 亚洲精品中文字幕| 日本免费大黄在线观看| 奇米精品视频一区二区三区| 亚洲欲色欲色xxxxx在线观看| 午夜伦费影视在线观看| 亚洲中文字幕无码爆乳av| 成年女人免费v片| 日日摸日日碰夜夜爽无码| 国产无遮挡18禁无码网站免费| 久久综合伊人77777| 亚洲国产精品一区二区第四页| 久久国产超碰女女av| 熟女少妇人妻中文字幕| 国产a√精品区二区三区四区| 欧美性生交xxxxx无码久久久 | 国产精品久久久久久成人影院| 一本无码中文字幕在线观|