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  4. DCTN4 Antibody

DCTN4 Antibody

  • 中文名稱：
    DCTN4兔多克隆抗體
  • 貨號：
    CSB-PA006567GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    DCTN4
  • 別名：
    DCTN 4 antibody; Dctn4 antibody; DCTN4_HUMAN antibody; Dynactin 4 (p62) antibody; Dynactin 4 antibody; Dynactin p62 subunit antibody; Dynactin subunit 4 antibody; Dynactin subunit p62 antibody; Dynactin4 antibody; p62 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human DCTN4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
  • 基因功能參考文獻(xiàn)：
    1. Findings provide evidence that DCTN4 missense variants, especially p.Tyr263Cys, may be involved in the pathogenesis of chronic Pseudomonas aeruginosa infection in male with cystic fi brosis. PMID: 25763772
    2. used an extreme phenotype study to discover that variants in DCTN4, encoding a dynactin protein, are associated with time to first P. aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis PMID: 22772370
    3. ATP7B interaction with p62 is a key component of the copper-induced trafficking pathway that delivers ATP7B to subapical vesicles of hepatocytes for the removal of excess copper into bile PMID: 16554302
  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cytoplasm, myofibril, sarcomere.
  • 蛋白家族：
    Dynactin subunit 4 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 15518

    OMIM: 614758

    KEGG: hsa:51164

    STRING: 9606.ENSP00000414906

    UniGene: Hs.675564



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