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DCTN4 Antibody

  • 中文名稱:
    DCTN4兔多克隆抗體
  • 貨號:
    CSB-PA892445LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate, Jurkat whole cell lysate, HEK293 whole cell lysate, SH-SY5Y whole cell lysate
      All lanes: DCTN4 antibody at 3.4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 53, 46, 54 kDa
      Observed band size: 53 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DCTN4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DCTN4
  • 別名:
    DCTN 4 antibody; Dctn4 antibody; DCTN4_HUMAN antibody; Dynactin 4 (p62) antibody; Dynactin 4 antibody; Dynactin p62 subunit antibody; Dynactin subunit 4 antibody; Dynactin subunit p62 antibody; Dynactin4 antibody; p62 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Dynactin subunit 4 protein (2-460AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,DCTN4 Antibody (CSB-PA892445LA01HU),的標記方式是Non-conjugated。對于DCTN4 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA892445LB01HU DCTN4 Antibody, HRP conjugated ELISA
    FITC CSB-PA892445LC01HU DCTN4 Antibody, FITC conjugated
    Biotin CSB-PA892445LD01HU DCTN4 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
  • 基因功能參考文獻:
    1. Findings provide evidence that DCTN4 missense variants, especially p.Tyr263Cys, may be involved in the pathogenesis of chronic Pseudomonas aeruginosa infection in male with cystic fi brosis. PMID: 25763772
    2. used an extreme phenotype study to discover that variants in DCTN4, encoding a dynactin protein, are associated with time to first P. aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis PMID: 22772370
    3. ATP7B interaction with p62 is a key component of the copper-induced trafficking pathway that delivers ATP7B to subapical vesicles of hepatocytes for the removal of excess copper into bile PMID: 16554302
  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm, cell cortex. Cytoplasm, myofibril, sarcomere.
  • 蛋白家族:
    Dynactin subunit 4 family
  • 數據庫鏈接:

    HGNC: 15518

    OMIM: 614758

    KEGG: hsa:51164

    STRING: 9606.ENSP00000414906

    UniGene: Hs.675564



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