在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

D2HGDH Antibody

  • 中文名稱:
    D2HGDH兔多克隆抗體
  • 貨號:
    CSB-PA006476GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    D2HGDH
  • 別名:
    D2HGDH antibody; D2HGDD-2-hydroxyglutarate dehydrogenase antibody; mitochondrial antibody; EC 1.1.99.- antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human D2HGDH
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate. Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC). Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC.
  • 基因功能參考文獻:
    1. D2HGDH-GAL3ST2 is more frequently seen in prostate cancer samples, and seems to be enriched in African Americans. PMID: 27322736
    2. D2HGDH elevates alpha-KG levels via IDH2 expression modulation, influencing histone and DNA methylation, and HIF1alpha hydroxylation. D2HGDH mutants found in diffuse large B-cell lymphoma are enzymatically inert. PMID: 26178471
    3. D2HGDH mutation is not associated with glioblastoma. PMID: 21625441
    4. We did not find evidence for mutations in the genes D2HGDH and L2HGDH as an alternative mechanism for raised 2-hydroxyglutarate levels in brain tumours PMID: 20727073
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20727073
    6. Two novel pathogenic mutations in D-2-hydroxyglutarate dehydrogenase gene in patient with a mild presentation and asymptomatic siblings with D-2-hydroxyglutaric aciduria with a splice error (IVS4-2A-->G) and a missense mutation (c.1315A-->G;p.Asn439Asp). PMID: 16037974
    7. This enzyme assay will have utility in differentiating patients with 2-hydroxyglutaric aciduria and in assessing the residual activities linked to pathogenic mutations in the D2HGDH gene PMID: 19283509

    顯示更多

    收起更多

  • 相關疾病:
    D-2-hydroxyglutaric aciduria 1 (D2HGA1)
  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    FAD-binding oxidoreductase/transferase type 4 family
  • 數據庫鏈接:

    HGNC: 28358

    OMIM: 600721

    KEGG: hsa:728294

    STRING: 9606.ENSP00000315351

    UniGene: Hs.516813



主站蜘蛛池模板: 亚洲 另类 在线 欧美 制服| 国内精品自在自线| 一本本月无码-| 激情偷乱人伦小说视频| 国产裸体xxxx视频在线播放| 牲交欧美兽交欧美| 亚洲 自拍 另类 欧美 综合| 在线观看国产成人av片| 国产精品麻豆aⅴ人妻| 久久国产免费直播| 成 人 色 网 站免费观看| 久久天天躁夜夜躁狠狠i女人| 777米奇影院狠狠色| 国产玉足榨精视频在线观看| 免费萌白酱国产一区二区三区| 无码熟熟妇丰满人妻啪啪| 乌克兰美女浓毛bbw| 超碰免费公开| 亚洲精品久久久蜜桃| 无码国内精品久久人妻蜜桃| 色夜码无码av网站| 人妻少妇中文字幕久久| 人妻丝袜av中文系列先锋影音| 国产成人毛片无码视频软件| 人人人妻人人人妻人人人| 偷拍区清纯另类丝袜美腿| 日本高清www午色夜在线视频 | 四川丰满少妇被弄到高潮| 人人妻人人澡人人爽欧美一区| 日韩av爽爽爽久久久久久| av片在线观看永久免费| 大地资源网第二页免费观看 | 精品少妇人妻av免费久久久| 在线亚洲日产一区二区| 国产边摸边吃奶边叫做激情视频| 亚洲性啪啪无码av天堂| 成人免费视频在线观看| 中文字幕v亚洲日本在线电影| 内射白浆一区二区在线观看| 51久久成人国产精品麻豆| 欧美成人一卡二卡三卡四卡|