在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Cd63 Antibody, HRP conjugated

Cd63 Antibody, HRP conjugated

  • 中文名稱：
    Cd63兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA004950EB01MO
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Mus musculus (Mouse) Cd63 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    Cd63
  • 別名：
    Cd63CD63 antigen antibody; CD antigen CD63 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Mouse
  • 免疫原：
    Recombinant Mouse CD63 antigen protein (103-203AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
  • 基因功能參考文獻：
    1. In renal proximal tubules, CD63 determines the insertion of OCT2 into the proper membrane domain and mediates transporter regulation by trafficking processes. PMID: 28031320
    2. TIMP1 signaling via CD63 leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells. PMID: 27506299
    3. The Muted protein is important for the steady-state level of CD63. PMID: 27531610
    4. Data show that CD63 is a crucial player in the regulation of the tumor cell-intrinsic metastatic potential by affecting cell plasticity. PMID: 25354204
    5. These findings identify CD63 as an important component of allergic inflammation. PMID: 23945142
    6. CD63 serves to bridge between beta1 integrin and VEGFR2 because CD63 silencing disrupted VEGFR2-beta1 integrin complex formation identified using proximity ligation assay PMID: 23632027
    7. Loss of CD63 is associated impairment of amyloidogenesis and downstream melanosome morphogenesis. PMID: 21962903
    8. Loss of CD63 has a similar phenotype to loss of P-selectin itself, thus CD63 is an essential cofactor to P-selectin. PMID: 21803846
    9. CXCR4 can be downregulated on activated B cells by IL-21-induced endocytosis and CD63-mediated endosomal recruitment. PMID: 21270405
    10. The findings identify palmitoylation-dependent association with the tetraspanin CD63 as the mechanism by which Syt VII is targeted to lysosomes. PMID: 21041449
    11. CD63, but not RILP, is recruited to the phagosomes in macrophages expressing the dominant negative form of Rab7. PMID: 20236428
    12. CD63 is recruited to already-budded Weibel-Palade bodies by an AP-3-dependent route PMID: 16683915
    13. Upon phagocytosis of Cryptococcus neoformans and polystyrene beads, CD63 was recruited selectively to C. neoformans-containing phagosomes in a MyD88-independent acidification-dependent manner PMID: 17043215
    14. protein region defined by amino acid residues 103-205 for CD63 interacts with amelogenin PMID: 17708745
    15. CD63 knockout mice show an increased urinary flow, water intake, reduced urine osmolality, and a higher fecal water content. PMID: 19075008
    16. the activation-induced degranulation of Fas ligand has distinct requirements and involves different mechanisms than those of the granule markers CD63 and CD107a/Lamp-1 PMID: 19079288

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endosome, multivesicular body. Melanosome. Secreted, extracellular exosome. Cell surface.
  • 蛋白家族：
    Tetraspanin (TM4SF) family
  • 組織特異性：
    Ubiquitous. Strongly expressed in kidney. Detected in spleen, bone marrow, peripheral blood mononuclear cells and macrophages.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 三级做爰高清视频| 丰满人妻一区二区三区无码av| 亚洲 欧美 另类图片| 少妇爽到呻吟的视频| 无码人妻黑人中文字幕| 国产精品露脸国语对白| 最近免费中文字幕中文高清百度| 日韩人妻无码一区二区三区综合| 国产成人精品高清在线观看93| 无码无套少妇毛多18pxxxx| 国模少妇一区二区三区| 孕妇怀孕高潮潮喷视频孕妇| 青青视频免费观看免费| 毛片无码国产| 欧美性猛交xxxx黑人| 东京热无码一区二区三区av| 伊人久久精品无码二区麻豆| 色一情一区二区三区四区| 午夜美女裸体福利视频| 少妇无码av无码专线区大牛影院| a亚洲va欧美va国产综合| а√中文在线资源库| 日日摸夜夜摸狠狠摸婷婷| 丰满少妇人妻无码| 精品一区精品二区制服| 亚洲aⅴ永久无码一区二区三区| 天天影视性色香欲综合网| 亚洲成av人片在线观看www| 久久精品人妻一区二区三区| 少妇大叫太大太爽受不了在线观看| 欧美午夜刺激影院| 亚洲产国偷v产偷v自拍色戒| 日本天天黄网站| 国产aⅴ夜夜欢一区二区三区| 99精品无人区乱码在线观看| 2020最新国产高清毛片| 午夜影视免费x看| 色综合中文综合网| 国产九九99久久99大香伊| 第一亚洲中文久久精品无码| 野花社区视频在线观看|