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CYP4B1 Antibody

  • 中文名稱:
    CYP4B1兔多克隆抗體
  • 貨號:
    CSB-PA006448GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CYP4B1
  • 別名:
    CP4B1_HUMAN antibody; CYP4B1 antibody; CYPIVB1 antibody; Cytochrome P450 4B1 antibody; Cytochrome P450 family 4 subfamily B polypeptide 1 antibody; Cytochrome P450 subfamily IVB polypeptide 1 antibody; Cytochrome P450-HP antibody; Microsomal monooxygenase antibody; P450HP antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CYP4B1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  • 基因功能參考文獻:
    1. the Ser207 insertion does not rescue the P450 functional activity of human CYP4B1 that has been lost during evolution. PMID: 26355749
    2. A proline residue in the meander region at position 427 in human CYP4B1 and 422 in rabbit CYP4B1 is important for protein stability and rescues the 4-ipomeanol bioactivation. PMID: 25247810
    3. polymorphism in humans: evidence for a non-functional allelic variant PMID: 12142726
    4. CYP4B1 is a senescene-associated gene in normal human oral keratinocytes. PMID: 12837283
    5. Results demostrated an increased risk of bladder cancer associated with the CYP4B1*1/*2 and *2/*2 genotypes. PMID: 18713828

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  • 亞細胞定位:
    Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
  • 蛋白家族:
    Cytochrome P450 family
  • 組織特異性:
    Detected in the liver and lung (at protein level).
  • 數據庫鏈接:

    HGNC: 2644

    OMIM: 124075

    KEGG: hsa:1580

    STRING: 9606.ENSP00000360991

    UniGene: Hs.436317



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