在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CXXC5 Antibody

  • 中文名稱:
    CXXC5兔多克隆抗體
  • 貨號:
    CSB-PA741975LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA741975LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA741975LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CXXC5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CXXC5
  • 別名:
    CF5 antibody; CXXC finger 5 protein antibody; CXXC finger protein 5 antibody; CXXC-type zinc finger protein 5 antibody; CXXC5 antibody; CXXC5_HUMAN antibody; HSPC195 antibody; Putative MAPK-activating protein PM08 antibody; Putative NF-kappa-B-activating protein 102 antibody; retinoid-inducible nuclear factor antibody; RINF antibody; TCCCIA00297 antibody; WID antibody; WT1-induced Inhibitor of Dishevelled antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human CXXC-type zinc finger protein 5 protein (1-227AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,CXXC5 Antibody (CSB-PA741975LA01HU),的標記方式是Non-conjugated。對于CXXC5 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA741975LB01HU CXXC5 Antibody, HRP conjugated ELISA
    FITC CSB-PA741975LC01HU CXXC5 Antibody, FITC conjugated
    Biotin CSB-PA741975LD01HU CXXC5 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ. Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG.
  • 基因功能參考文獻:
    1. show here that CXXC5 is an E2-ERalpha responsive gene regulated by the interaction of E2-ERalpha with an ERE present at a region upstream of the initial translation codon of the gene PMID: 27886276
    2. High CXXC5 expression seems to affect several steps in human leukemogenesis, including intracellular events as well as extracellular communication. PMID: 25605239
    3. Findings suggest that overexpression of CXXC5 in C2C12 myoblasts facilitated myocyte differentiation, while RNAi interference of CXXC5 significantly inhibited the differentiation of C2C12 myoblasts. PMID: 25433557
    4. Low CXXC5 expression is associated with acute myeloid leukemia. PMID: 25805812
    5. targeting of CXXC5/RINF should be considered as a possible therapeutic strategy, especially in high-risk patients who show increased expression in AML cells compared with normal hematopoietic cells PMID: 23988457
    6. Lack of promoter hypermethylation or somatic mutations are found in the potential tumor suppressor CXXC5 in myelodysplastic syndromes or acute myeloid leukemia with deletion 5q. PMID: 23190153
    7. RINF overexpression represents an independent molecular marker for poor prognosis in breast tumors. PMID: 21325450
    8. RINF expression correlates with retinoid-induced differentiation of leukemic cells and with cytokine-induced myelopoiesis of normal CD34(+) progenitors. PMID: 19182210
    9. These findings suggest that CF5 plays a crucial role in ATM-p53 signaling in response to DNA damage. PMID: 19557330

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 數據庫鏈接:

    HGNC: 26943

    OMIM: 612752

    KEGG: hsa:51523

    STRING: 9606.ENSP00000302543

    UniGene: Hs.189119



主站蜘蛛池模板: 国产乱码一区二区三区| 久久精品中文字幕第一页| 美女网站免费福利视频| 国产成人午夜高潮毛片| 亚洲日韩国产一区二区三区| 天干天干夜啦天干天干国产| 亚洲色大成网站久久久| 久久精品国产精品亚洲毛片| 中文精品无码中文字幕无码专区| 欧美黑人巨大videos在线| 午夜免费啪在线观看视频 | 亚洲精品一区中文字幕乱码| 日本久久高清一区二区三区毛片| 国内熟妇人妻色无码视频在线| 国产在线精品二区| 性按摩xxxx在线观看| 在线毛片片免费观看| 国产老熟女狂叫对白| 国产精品妇女一二三区| 国产农村妇女aaaaa视频| 精品国产福利久久久| 午夜不卡无码中文字幕影院| 亚洲熟妇色自偷自拍另类| 在线观看免费视频污网站| 成人无码专区免费播放三区| 无码一区二区三区在线| 各处沟厕大尺度偷拍女厕嘘嘘| 最新国产精品好看的精品 | 亚洲精品92内射| 女性自慰网站免费看ww| 国产麻豆精品福利在线观看| 一本一道久久综合狠狠老| 青青草国产精品日韩欧美| 国产清纯美女遭强到高潮| 岛国av动作片在线观看| 欧美大屁股xxxx高跟欧美黑人 | 人妻中文字幕乱人伦在线| 粗大的内捧猛烈进出少妇视频| 国产成人高清精品亚洲| 国产精品www夜色视频| 偷欧洲亚洲另类图片av天堂|