在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CXXC5 Antibody

CXXC5 Antibody

  • 中文名稱：
    CXXC5兔多克隆抗體
  • 貨號：
    CSB-PA806953
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA806953(CXXC5 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA806953(CXXC5 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    CXXC5
  • 別名：
    CF5 antibody; CXXC finger 5 protein antibody; CXXC finger protein 5 antibody; CXXC-type zinc finger protein 5 antibody; CXXC5 antibody; CXXC5_HUMAN antibody; HSPC195 antibody; Putative MAPK-activating protein PM08 antibody; Putative NF-kappa-B-activating protein 102 antibody; retinoid-inducible nuclear factor antibody; RINF antibody; TCCCIA00297 antibody; WID antibody; WT1-induced Inhibitor of Dishevelled antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human CXXC5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ. Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG.
  • 基因功能參考文獻：
    1. show here that CXXC5 is an E2-ERalpha responsive gene regulated by the interaction of E2-ERalpha with an ERE present at a region upstream of the initial translation codon of the gene PMID: 27886276
    2. High CXXC5 expression seems to affect several steps in human leukemogenesis, including intracellular events as well as extracellular communication. PMID: 25605239
    3. Findings suggest that overexpression of CXXC5 in C2C12 myoblasts facilitated myocyte differentiation, while RNAi interference of CXXC5 significantly inhibited the differentiation of C2C12 myoblasts. PMID: 25433557
    4. Low CXXC5 expression is associated with acute myeloid leukemia. PMID: 25805812
    5. targeting of CXXC5/RINF should be considered as a possible therapeutic strategy, especially in high-risk patients who show increased expression in AML cells compared with normal hematopoietic cells PMID: 23988457
    6. Lack of promoter hypermethylation or somatic mutations are found in the potential tumor suppressor CXXC5 in myelodysplastic syndromes or acute myeloid leukemia with deletion 5q. PMID: 23190153
    7. RINF overexpression represents an independent molecular marker for poor prognosis in breast tumors. PMID: 21325450
    8. RINF expression correlates with retinoid-induced differentiation of leukemic cells and with cytokine-induced myelopoiesis of normal CD34(+) progenitors. PMID: 19182210
    9. These findings suggest that CF5 plays a crucial role in ATM-p53 signaling in response to DNA damage. PMID: 19557330

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 數據庫鏈接：

    HGNC: 26943

    OMIM: 612752

    KEGG: hsa:51523

    STRING: 9606.ENSP00000302543

    UniGene: Hs.189119



主站蜘蛛池模板： 亚洲精品tv久久久久久久久久| 久久午夜神器| 亚洲 成人 无码 在线观看| 国产偷人妻精品一区二区在线| 国产自偷在线拍精品热| 国产成人18黄网站| 久久精品国产清自在天天线| 国产一区二区三区成人欧美日韩在线观看| 久久精品国产99久久6动漫| 国产三级视频在线播放线观看| 国产精品福利视频导航| 免费无码又爽又刺激高潮| 亚洲高清无在码在线电影| 99这里有精品视频视频| 亚洲性猛交xxxx| 先锋影音男人av资源| 亚洲一区二区三区成人网站| 国产日韩av无码免费一区二区| 18禁止观看强奷免费国产大片| 婷婷射精av这里只有精品| 天堂а√在线中文在线| 欧美黑人异族videos| 欧美35页视频在线观看| 亚洲色精品aⅴ一区区三区| 亚洲日韩国产一区二区三区| 亚洲乱码在线卡一卡二卡新区豆瓣| 国产欧美亚洲精品a第一页| 秋霞在线观看秋| 人妻无码中文字幕一区二区三区 | 秋霞av在线露丝片av无码| 精品露脸国产偷人在视频| 亚洲春色在线视频| 中文字幕日本最新乱码视频| 久爱www人成免费网站| 国内揄拍国内精品少妇| 天堂网在线最新版www资源网| 一边啪啪的一边呻吟声口述| 色婷婷亚洲一区二区综合| 欧美精品videosex性欧美| 加勒比无码人妻东京热| 人人莫人人擦人人看|