在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CXXC1 Antibody

  • 中文名稱:
    CXXC1兔多克隆抗體
  • 貨號:
    CSB-PA006300GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CXXC1
  • 別名:
    2410002I16Rik antibody; 5830420C16Rik antibody; AI426635 antibody; CFP 1 antibody; CFP1 antibody; CpG binding protein antibody; CpG-binding protein antibody; CXXC 1 antibody; CXXC finger 1 antibody; CXXC finger 1 PHD domain antibody; CXXC finger protein 1 antibody; CXXC type zinc finger protein 1 antibody; CXXC-type zinc finger protein 1 antibody; CXXC1 antibody; CXXC1_HUMAN antibody; DNA binding protein with PHD finger and CXXC domain antibody; hCGBP antibody; HsT2645 antibody; PCCX 1 antibody; PCCX1 antibody; PHD finger and CXXC domain containing protein 1 antibody; PHD finger and CXXC domain-containing protein 1 antibody; PHF 18 antibody; PHF18 antibody; Protein containing CXXC domain 1 antibody; SPP 1 antibody; SPP1 antibody; ZCGPC 1 antibody; ZCGPC1 antibody; Zinc finger; CpG binding type containing 1 antibody
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CXXC1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.
  • 基因功能參考文獻:
    1. CFP1 binds open chromatin regions of active genes, including enhancers and non-CpG islands. PMID: 30292235
    2. directly controls the expression of key genes important for thymocyte survival, such as RORgammat, and for T-cell receptor signaling, including Zap70 and CD8, through maintaining the appropriate H3K4me3 on their promoters PMID: 27210293
    3. NF-kappaB recruitment enhanced the occupancy of the CpG island within the 14-3-3gamma promoter by CFP1.14-3-3gamma induction in CSR is enabled by the CFP1-mediated H3K4me3 enrichment in the promoter, dependent on NF-kappaB and sustained by E2A. PMID: 23851690
    4. The crescent-shaped CFP1 CXXC domain is wedged into the major groove of the CpG DNA, distorting the B-form DNA, and interacts extensively with the major groove of the DNA. PMID: 21407193
    5. CXXC finger protein 1 is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex PMID: 16253997
    6. CXXC finger protein 1 is required for normal proliferation and differentiation of the PLB-985 myeloid cell line. PMID: 17328666
    7. CGBP interacts with MLL1, MLL2 as well as Set1 H3-Lysine 4 (H3K4) specific methyl-transferases and plays critical roles in regulations of MLL target genes. PMID: 18082152
    8. study shows endogenous DNMT1 & CFP1 interact in vivo; CFP1 interaction with Setd1A or Setd1B not required for its interaction with DNMT1; result indicates CFP1 intersects cytosine methylation machinery independently of its association with Setd1 complexes PMID: 18680430
    9. expression of either the amino half of Cfp1 (amino acids 1 to 367 [Cfp1(1-367)]) or the carboxyl half of Cfp1 (Cfp1(361-656)) is sufficient to correct all of the defects observed with embryonic stem cells that lack Cfp1 PMID: 19433449

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus speckle. Nucleus. Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes.
  • 組織特異性:
    Ubiquitous.
  • 數據庫鏈接:

    HGNC: 24343

    OMIM: 609150

    KEGG: hsa:30827

    STRING: 9606.ENSP00000390475

    UniGene: Hs.180933



主站蜘蛛池模板: 国产精品亚洲五月天高清| 中文字幕高清免费日韩视频在线| 亚洲人成网站999久久久综合| 久久免费的精品国产v∧| 中文字幕无码不卡免费视频| 亚洲第一成年免费网站| 亚在线第一国产州精品99| 亚洲日韩国产中文其他| 色欲久久久中文字幕综合网| 亚洲熟妇中文字幕五十中出| 日本乱人伦在线观看| 中文字幕人妻熟女人妻洋洋| 久久久久免费看成人影片| 熟女俱乐部五十路六十路| 黑色丝袜无码中中文字幕| 久久无码专区国产精品| 亚洲精华国产精华精华液网站| 欧美激情内射喷水高潮| 麻豆精产一二三产区| 久久国产欧美成人av| 狠狠色丁香久久婷婷综合蜜芽五月 | 亚洲在av人极品无码| 欧美三級片黃色三級片黃色| 成人免费精品网站在线观看影片| 狠狠色狠狠色综合网| 精品国产乱码久久久久久影片 | 人妻熟女久久久久久久| 好爽好黄的视频| 国产高清在线a视频大全| 狠狠色噜噜狠狠狠狠色综合久| 99热成人精品热久久6网站| 天堂网www天堂资源网| 国产高清在线精品一区免费| 国产一精品一av一免费| 久久发布国产伦子伦精品| 337p人体 欧洲人体 亚洲| 久久久久国色av∨免费看| 亚洲伊人成综合网| 少妇熟女高潮流白浆| 欧美日韩人人模人人爽人人喊| 超碰97人人做人人爱亚洲尤物|