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CST7 Antibody

  • 中文名稱:
    CST7兔多克隆抗體
  • 貨號:
    CSB-PA006095GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CST7
  • 別名:
    CMAP antibody; CST 7 antibody; Cst7 antibody; Cystatin 7 antibody; cystatin F (leukocystatin) antibody; Cystatin like metastasis associated protein antibody; Cystatin-7 antibody; Cystatin-F antibody; Cystatin-like metastasis-associated protein antibody; Cystatin7 antibody; CystatinF antibody; CYTF_HUMAN antibody; dJ568C11.1 antibody; Leukocystatin antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CST7
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
  • 基因功能參考文獻:
    1. during monocyte to macrophage differentiation, the endosomal/lysosomal proteolytic activity can be regulated by cystatin F whose expression is under the control of transcriptional factor C/EBP alpha. PMID: 30033148
    2. Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells. PMID: 22365146
    3. Transgenic cystatin F is expressed in model mice only during demyelination; in chronic demyelination, remyelinating ability is lost. PMID: 21344476
    4. cystatin F is an intracellular cysteine peptidase inhibitor with readily regulated expression PMID: 12423348
    5. CST7 is secreted, but artificial modification of its C-terminus can induce its endocytic targeting. PMID: 15212960
    6. Cystatin F was not colocalized with cystatin C shich suggests distinct functions for these two cysteine protease inhibitors in U937 cells. PMID: 15752368
    7. analysis of reduction-dependent activation of human cystatin F PMID: 16601115
    8. A latent protease inhibitor which is itself regulated by proteolysis in the endocytic pathway. PMID: 18256700
    9. Data demonstrate the addition of N-linked sugars to an Asn-X-Cys motif in cystatin F and suggest that the mannose 6-phosphate sorting machinery is used to divert cystatin F from the secretory pathway and to mediate its uptake from extracellular pools. PMID: 19192250

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  • 亞細胞定位:
    Secreted. Cytoplasm.
  • 蛋白家族:
    Cystatin family
  • 組織特異性:
    Primarily expressed in peripheral blood cells and spleen.
  • 數據庫鏈接:

    HGNC: 2479

    OMIM: 603253

    KEGG: hsa:8530

    STRING: 9606.ENSP00000420384

    UniGene: Hs.143212



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