在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CRTAP Antibody

  • 中文名稱:
    CRTAP兔多克隆抗體
  • 貨號:
    CSB-PA005999ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: CRTAP antibody at 0.96µg/ml
      Lane 1: 293T whole cell lysate
      Lane 2: Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 47 kDa
      Observed band size: 47 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA005999ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA005999ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CRTAP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CRTAP
  • 別名:
    CRTAP antibody; CASPCartilage-associated protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Cartilage-associated protein (20-240AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues.
  • 基因功能參考文獻:
    1. To the best of our knowledge, our study is the first to exclude potential correlations between heterozygous variants in CRTAP and milder skeletal impairments in a large number of patients PMID: 27901313
    2. This study enhances our knowledge about the mutational pattern of the LEPRE1, CRTAP, and PPIB genes. LEPRE1 should be the first gene analyzed in mutation detection studies in patients with recessive OI. PMID: 26634552
    3. An additional function of the rough endoplasmic reticulum protein complex prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B: the CXXXC motif reveals disulfide isomerase activity in vitro. PMID: 24043621
    4. SNP rs7623768 and the haplotype G-C of rs4076086-rs7623768 in CRTAP were associated with femoral neck bone mineral density (p = 0.009 and p = 0.003, respectively). PMID: 19727905
    5. Importantly, human mutations in the CRTAP gene have been associated with recessive forms of OI. PMID: 20425614
    6. CRTAP deficiency results in higher bone mineral content of the bone matrix in osteogenesis imperfecta type VII. PMID: 19895918
    7. Null mutations in LEPRE1 and CRTAP cause severe recessive osteogenesis imperfecta. PMID: 19862557
    8. CRTAP and P3H1 are mutually stabilized in the collagen prolyl 3-hydroxylation complex in endoplasmic reticulum. PMID: 19846465
    9. CRTAP mutations not described earlier were identified in 10 individuals who had a clinical diagnosis of lethal and severe osteogenesis imperfecta. PMID: 19550437
    10. complexes with prolyl 3-hydroxylase 1 (P3H1) to decrease prolyl 3 hydroxylation; dysregulation of prolyl 3 hydroxylation is a mechanism for connective tissue disease PMID: 17055431
    11. Screening of 78 subjects diagnosed with osteogenesis imperfecta type II or III, identified three probands with mutations in CRTAP and 16 with mutations in LEPRE1. PMID: 18566967
    12. Mutations in CRTAP and LEPRE1 are found in 3 patients with type II osteogenesis imperfecta. PMID: 18996919

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Osteogenesis imperfecta 7 (OI7)
  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Leprecan family
  • 組織特異性:
    Found in articular chondrocytes. Expressed in a variety of tissues.
  • 數據庫鏈接:

    HGNC: 2379

    OMIM: 605497

    KEGG: hsa:10491

    STRING: 9606.ENSP00000323696

    UniGene: Hs.517888



主站蜘蛛池模板: 久久99亚洲精品久久频| 狠狠久久噜噜熟女| 久久97久久97精品免视看秋霞 | 强 暴 疼 哭 处 女 身子视频| 国产日韩在线视看第一页| 久久成人影院精品777| 医院人妻闷声隔着帘子被中出 | 高清免费精品国自产拍| 后入内射国产一区二区| 国产精品无码永久免费不卡| 久久精品成人免费国产片小草 | 8888四色奇米在线观看| 精品久久久久久久免费人妻| 成人国产片视频在线观看| 国产免费不卡av在线播放| 农村欧美丰满熟妇xxxx| 老妇肥熟凸凹丰满刺激| 精品国产你懂的在线观看| 96亚洲精华国产精华精华液| 青草草在线视频永久免费| 中文乱码人妻系列一区二区| 国产欧洲精品自在自线官方| 国产精品无码一区二区三级| 无码夜色一区二区三区| 1区2区3区高清视频| 日韩在线 | 中文| 沈阳45老熟女高潮喷水亮点| 蜜桃成人无码区免费视频网站| 又大又粗又爽又黄的少妇毛片| 九色porny丨自拍视频| 亚洲精品乱码久久久久久日本| 日韩精品无码成人专区| 免费午夜福利不卡片在线| 久久99国产综合精品| 天天干天天日| 男女做爰猛烈啪啪吃奶动| 欧美午夜精品久久久久免费视| 国产精品99久久久久久www| 国产成+人+综合+亚洲专区| 欧美日本日韩| 天天噜日日噜狠狠噜免费 |