在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CRTAP Antibody

CRTAP Antibody

  • 中文名稱：
    CRTAP兔多克隆抗體
  • 貨號(hào)：
    CSB-PA005999GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CRTAP
  • 別名：
    CRTAP antibody; CASPCartilage-associated protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human CRTAP
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues.
  • 基因功能參考文獻(xiàn)：
    1. To the best of our knowledge, our study is the first to exclude potential correlations between heterozygous variants in CRTAP and milder skeletal impairments in a large number of patients PMID: 27901313
    2. This study enhances our knowledge about the mutational pattern of the LEPRE1, CRTAP, and PPIB genes. LEPRE1 should be the first gene analyzed in mutation detection studies in patients with recessive OI. PMID: 26634552
    3. An additional function of the rough endoplasmic reticulum protein complex prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B: the CXXXC motif reveals disulfide isomerase activity in vitro. PMID: 24043621
    4. SNP rs7623768 and the haplotype G-C of rs4076086-rs7623768 in CRTAP were associated with femoral neck bone mineral density (p = 0.009 and p = 0.003, respectively). PMID: 19727905
    5. Importantly, human mutations in the CRTAP gene have been associated with recessive forms of OI. PMID: 20425614
    6. CRTAP deficiency results in higher bone mineral content of the bone matrix in osteogenesis imperfecta type VII. PMID: 19895918
    7. Null mutations in LEPRE1 and CRTAP cause severe recessive osteogenesis imperfecta. PMID: 19862557
    8. CRTAP and P3H1 are mutually stabilized in the collagen prolyl 3-hydroxylation complex in endoplasmic reticulum. PMID: 19846465
    9. CRTAP mutations not described earlier were identified in 10 individuals who had a clinical diagnosis of lethal and severe osteogenesis imperfecta. PMID: 19550437
    10. complexes with prolyl 3-hydroxylase 1 (P3H1) to decrease prolyl 3 hydroxylation; dysregulation of prolyl 3 hydroxylation is a mechanism for connective tissue disease PMID: 17055431
    11. Screening of 78 subjects diagnosed with osteogenesis imperfecta type II or III, identified three probands with mutations in CRTAP and 16 with mutations in LEPRE1. PMID: 18566967
    12. Mutations in CRTAP and LEPRE1 are found in 3 patients with type II osteogenesis imperfecta. PMID: 18996919

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Osteogenesis imperfecta 7 (OI7)
  • 亞細(xì)胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Leprecan family
  • 組織特異性：
    Found in articular chondrocytes. Expressed in a variety of tissues.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 2379

    OMIM: 605497

    KEGG: hsa:10491

    STRING: 9606.ENSP00000323696

    UniGene: Hs.517888



主站蜘蛛池模板： 性欧美欧美巨大69| 国产在线乱子伦一区二区| 麻豆md0077饥渴少妇| 国产丰满麻豆videossexhd | 两个黑人大战嫩白金发美女| 无码人中文字幕| 精品少妇人妻av久久久| 人人爽人人澡人人人妻、百度| 国产人成无码视频在线观看| 国产思思99re99在线观看| 色欲天天网站欧美成人福利网| 日韩精品一卡2卡3卡4卡新区视频 国产亚洲精品一区二三区 | 国产交换配偶在线视频| 香港三日本三级少妇三级66| av在线亚洲男人的天堂| 无遮挡男女激烈动态图| 亚洲色精品三区二区一区| 波多野结衣av手机在线观看| 精品玖玖玖视频在线观看| 久久天天躁狠狠躁夜夜2020老熟妇| 苍井空一区二区波多野结衣av| 国产午夜伦鲁鲁| 国产成人欧美日本在线观看| 国内精品伊人久久久久网站| 日本高清aⅴ毛片免费| 国产女人与公拘交在线播放| 裸体女人高潮毛片| 久久99精品久久久久子伦| 人妻互换 综合| 国产精品久久久久久无码五月| 丰满少妇被猛烈进入试看| 69精品人人人人| 粉嫩虎白女毛片人体| 亚洲精品乱码久久久久蜜桃| 日本va欧美va精品发布| 2021年国产精品专区丝袜| 久久九九精品国产免费看小说| 国产精品揄拍100视频| 人妻少妇av无码一区二区| 乱子伦av无码中文字| 亚洲午夜成人av电影|