在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CRTAP Antibody

CRTAP Antibody

  • 中文名稱：
    CRTAP兔多克隆抗體
  • 貨號(hào)：
    CSB-PA005999GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CRTAP
  • 別名：
    CRTAP antibody; CASPCartilage-associated protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human CRTAP
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues.
  • 基因功能參考文獻(xiàn)：
    1. To the best of our knowledge, our study is the first to exclude potential correlations between heterozygous variants in CRTAP and milder skeletal impairments in a large number of patients PMID: 27901313
    2. This study enhances our knowledge about the mutational pattern of the LEPRE1, CRTAP, and PPIB genes. LEPRE1 should be the first gene analyzed in mutation detection studies in patients with recessive OI. PMID: 26634552
    3. An additional function of the rough endoplasmic reticulum protein complex prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B: the CXXXC motif reveals disulfide isomerase activity in vitro. PMID: 24043621
    4. SNP rs7623768 and the haplotype G-C of rs4076086-rs7623768 in CRTAP were associated with femoral neck bone mineral density (p = 0.009 and p = 0.003, respectively). PMID: 19727905
    5. Importantly, human mutations in the CRTAP gene have been associated with recessive forms of OI. PMID: 20425614
    6. CRTAP deficiency results in higher bone mineral content of the bone matrix in osteogenesis imperfecta type VII. PMID: 19895918
    7. Null mutations in LEPRE1 and CRTAP cause severe recessive osteogenesis imperfecta. PMID: 19862557
    8. CRTAP and P3H1 are mutually stabilized in the collagen prolyl 3-hydroxylation complex in endoplasmic reticulum. PMID: 19846465
    9. CRTAP mutations not described earlier were identified in 10 individuals who had a clinical diagnosis of lethal and severe osteogenesis imperfecta. PMID: 19550437
    10. complexes with prolyl 3-hydroxylase 1 (P3H1) to decrease prolyl 3 hydroxylation; dysregulation of prolyl 3 hydroxylation is a mechanism for connective tissue disease PMID: 17055431
    11. Screening of 78 subjects diagnosed with osteogenesis imperfecta type II or III, identified three probands with mutations in CRTAP and 16 with mutations in LEPRE1. PMID: 18566967
    12. Mutations in CRTAP and LEPRE1 are found in 3 patients with type II osteogenesis imperfecta. PMID: 18996919

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Osteogenesis imperfecta 7 (OI7)
  • 亞細(xì)胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Leprecan family
  • 組織特異性：
    Found in articular chondrocytes. Expressed in a variety of tissues.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 2379

    OMIM: 605497

    KEGG: hsa:10491

    STRING: 9606.ENSP00000323696

    UniGene: Hs.517888



主站蜘蛛池模板： 一区二区乱子伦在线播放| 午夜免费福利小电影| 日日摸天天摸爽爽狠狠97| 欧美性开放情侣网站| 亚洲日韩欧美一区二区三区在线| 亚洲国产人成自精在线尤物| 亚洲爆乳成av人在线视菜奈实| 亚洲精品久久久久国产剧8| av无码免费永久在线观看| 亚洲电影在线观看| 免费无码成人片| 人妻无码一区二区三区tv| 亚洲综合一区国产精品| 久久国产精品_国产精品| 精品无码人妻一区二区三区| 国产精品美女久久久免费| 国产熟妇高潮呻吟喷水| 日本天天黄网站| 久久精品免费一区二区三区| 成人区人妻精品一区二区不卡网站 | 亚洲午夜无码av毛片久久| 欧美xxxxx高潮喷水麻豆| 欧美亚洲色aⅴ大片| 亚洲精品区午夜亚洲精品区| 极品粉嫩嫩模大尺度无码视频| 国产久热精品无码激情 | 国产成人综合日韩精品无码不卡 | 免费午夜福利不卡片在线播放| 精品无码黑人又粗又大又长| 国产女同疯狂作爱系列| 国产精品午夜福利不卡120| 日韩精品少妇无码受不了| 国产免费牲交视频| 久久久久无码精品亚洲日韩| 久久精品成人免费观看三| 亚洲欧美国产制服图片区| 亚洲色大成网站www永久男同| 黄页网站视频| 男女做爽爽爽视频免费软件| 少妇精品视频无码专区| 精品av无码国产一区二区|