在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CPSF4 Antibody

CPSF4 Antibody

  • 中文名稱：
    CPSF4兔多克隆抗體
  • 貨號：
    CSB-PA913267
  • 規(guī)格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, 293T cells, Primary antibody: CSB-PA913267(CPSF4 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CPSF4
  • 別名：
    cleavage and polyadenylation specific factor 4; 30kDa antibody; Cleavage and polyadenylation specificity factor 30 kDa subunit antibody; Cleavage and polyadenylation specificity factor subunit 4 antibody; cleavage polyadenylation specificity factor; 30kD antibody; CPSF 30 kDa subunit antibody; CPSF30 antibody; Cpsf4 antibody; CPSF4_HUMAN antibody; NAR antibody; Neb-1 antibody; NEB1 antibody; No arches homolog antibody; no arches like zinc finger protein antibody; NS1 effector domain binding protein 1 antibody; NS1 effector domain-binding protein 1 antibody; OTTHUMP00000206235 antibody; OTTHUMP00000206237 antibody; OTTHUMP00000206239 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human CPSF4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
  • 基因功能參考文獻(xiàn)：
    1. The authors define the molecular architecture of the core human CPSF complex comprising CPSF160, WDR33, CPSF30 and Fip1 and identify specific domains involved in inter-subunit interactions. Together, these results shed light on the function of CPSF in mediating polyA signal-dependent RNA cleavage and polyadenylation. PMID: 29274231
    2. Residues F103 and M106 within the NS1-CPSF4 binding region are important for viral replication. PMID: 28554059
    3. Cleavage and polyadenylation specific factor 4 targets NF-kappaB/cyclooxygenase-2 signaling to promote the growth and survival of non-small cell lung carcinoma cells. PMID: 27450326
    4. These findings support a role for iron in some zinc-finger proteins. Using electrophoretic mobility shift assays and fluorescence anisotropy, we report that CPSF30 selectively recognizes the AU-rich hexamer (AAUAAA) sequence present in pre-mRNA, providing the first molecular-based evidence to our knowledge for CPSF30/RNA binding. PMID: 27071088
    5. unexpectedly found that CPSF subunits CPSF30 and Wdr33 directly contact AAUAAA PMID: 25301780
    6. CPSF4 upregulates human TERT promoter activity, human TERT expression and telomerase activity. PMID: 24618080
    7. Data show that 4 drug-like compounds from traditional Chinese Medicine (TCM) database were selected as potential inhibitors for the cleavage and polyadenylation specific factor CPSF30-binding site of influenza A virus of non-structural protein 1 (NS1A). PMID: 24562912
    8. CPSF4 plays a critical role in regulating lung cancer cell proliferation and survival and may be a potential prognostic biomarker and therapeutic target for lung adenocarcinoma. PMID: 24358221
    9. Data show that the NS1A protein of the pathogenic H5N1 influenza A/Hong Kong/483/97 (HK97) virus isolated from humans has an intrinsic defect in CPSF30 binding. PMID: 17522219

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    CPSF4/YTH1 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2327

    OMIM: 603052

    KEGG: hsa:10898

    STRING: 9606.ENSP00000292476

    UniGene: Hs.489287



主站蜘蛛池模板： 日本亲与子乱人妻hd| 亚洲色大成网站www国产| 麻豆精产国品| 亚洲看片lutube在线观看| 极品粉嫩福利午夜在线播放| 国产成人欧美一区二区三区| 国产卡一卡二卡三无线乱码新区| 国产成人无码国产亚洲| 亚洲中文字幕在线精品2021| 国产高清在线精品一区免费| 亚洲 欧美 日韩 综合aⅴ| 97夜夜澡人人爽人人喊a| 国产成人av一区二区三区无码 | 色哟哟精品视频在线观看| 中国亚洲女人69内射少妇| 久久婷婷久久一区二区三区| 亚洲国产精品成人精品无码区| 婷婷综合久久中文字幕| √天堂资源地址中文在线| 日韩乱码在线观看免费视频网站| 少妇无码av无码专线区大牛影院| 久久午夜羞羞影院免费观看| 一边摸一边做爽的视频17国产| 中文字幕av无码不卡免费| 在线观看片a免费不卡观看| 国产成人综合久久亚洲精品| 国产精品成人永久在线| 婷婷色怡春院| 熟女少妇人妻中文字幕| 欧美不卡高清一区二区三区| 国产精品丝袜亚洲熟女| 成人午夜福利视频后入| 国产色无码精品视频国产| 亚洲国产欧美在线人成人| 国产成年女人毛片80s网站| 国产免费mv大片人人电影播放器| 亚洲精品无码av黄瓜影视| 国产片av国语在线观麻豆| 国产精品一卡二卡三卡四卡| 欧美熟妇性开放| 无人区一线二线三线乱码|