在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

COX5B Antibody

  • 中文名稱:
    COX5B兔多克隆抗體
  • 貨號:
    CSB-PA126082
  • 規格:
    ¥1100
  • 圖片:
    • Gel: 10+12%SDS-PAGE, Lysate: 40 μg, Lane: Human liver cancer tissue, Primary antibody: CSB-PA126082(COX5B Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    COX 5B antibody; COX5B antibody; COX5B_HUMAN antibody; COXVB antibody; Cytochrome c oxidase polypeptide Vb antibody; Cytochrome c oxidase polypeptide VB mitochondrial antibody; Cytochrome c oxidase subunit 5B antibody; Cytochrome c oxidase subunit 5B mitochondrial antibody; Cytochrome c oxidase subunit Vb antibody; mitochondrial antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human COX5B
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:200-1:1000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
  • 基因功能參考文獻:
    1. Our results suggest that COX5B protein level might be associated with tumor size. COX5B overexpression indicated a worse DFS (p < 0.05) in breast cancer. PMID: 28592145
    2. These experiments suggest that the FAD group of cytochrome b5 reductase increase its solvent exposition upon complex formation promoting an efficient electron transfer between the proteins. PMID: 29111436
    3. silence of COX5B leads to metabolic disorders, such as increased glucose uptake and decreased lactate secretion PMID: 26506233
    4. Transfected the A549 cells with COX Vb small interfering or shRNA and observed a significant reduction of their COX activity, oxygen consumption, ATP and ability to grow in soft agar and as poorly differentiated tumors in athymic mice. PMID: 22917272
    5. Data show that Bcl-2 expression positively influences the targeting of nuclear-encoded COX Va and Vb to the mitochondria of cancer cells. PMID: 19834492

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族:
    Cytochrome c oxidase subunit 5B family
  • 數據庫鏈接:

    HGNC: 2269

    OMIM: 123866

    KEGG: hsa:1329

    STRING: 9606.ENSP00000258424

    UniGene: Hs.1342



主站蜘蛛池模板: 日韩人妻潮喷中文在线视频| 国产精品久久婷婷六月丁香| 国产精品成人久久久久久久| 人人澡人摸人人添| 国产在不卡免费一区二区三| 2020国产精品午夜福利在线观看| 色在线 | 国产| 男女性杂交内射女bbwxz| 女人下面毛多水多视频| 国产午夜成人无码免费看不卡| 永久免费无码网站在线观看个| 日韩不卡1卡2卡三卡2021精品推荐 | 国产成人综合在线视频| 老太脱裤让老头玩ⅹxxxx | 亚洲人成小说网站色在线观看| 亚洲6080yy久久无码产自国产 | 国产av久久人人澡人人爱| 欧美人与禽zozzo性伦交| 午夜伦费影视在线观看| 996热re视频精品视频这里| 免费特级毛片| 欧美日韩精品无码一本二本三本色| 亚洲一区二区无码影院| 色一情一乱一乱一区99av白浆| 国产精品后入内射日本在线观看| 色综合色狠狠天天综合色| 国内精品国语自产拍在线观看 | 国产亚洲精品合集久久久久| 色屁屁www影院免费观看| 乌克兰少妇videos高潮| 大战熟女丰满人妻av| 欧美日产亚洲国产精品| 国产欧美日韩中文久久| 97久久超碰国产精品2021 | 猫咪www免费人成人入口| 久章草国语自产拍在线观看| 久久久久国色av∨免费看| 亚洲a∨无码男人的天堂| 欧美老妇与zozozo交| 精品少妇人妻av久久久| 日产精品一二三区|