在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

COX5B Antibody

  • 中文名稱:
    COX5B兔多克隆抗體
  • 貨號(hào):
    CSB-PA007159
  • 規(guī)格:
    ¥1090
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    COX 5B antibody; COX5B antibody; COX5B_HUMAN antibody; COXVB antibody; Cytochrome c oxidase polypeptide Vb antibody; Cytochrome c oxidase polypeptide VB mitochondrial antibody; Cytochrome c oxidase subunit 5B antibody; Cytochrome c oxidase subunit 5B mitochondrial antibody; Cytochrome c oxidase subunit Vb antibody; mitochondrial antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human COX5b.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
  • 基因功能參考文獻(xiàn):
    1. Our results suggest that COX5B protein level might be associated with tumor size. COX5B overexpression indicated a worse DFS (p < 0.05) in breast cancer. PMID: 28592145
    2. These experiments suggest that the FAD group of cytochrome b5 reductase increase its solvent exposition upon complex formation promoting an efficient electron transfer between the proteins. PMID: 29111436
    3. silence of COX5B leads to metabolic disorders, such as increased glucose uptake and decreased lactate secretion PMID: 26506233
    4. Transfected the A549 cells with COX Vb small interfering or shRNA and observed a significant reduction of their COX activity, oxygen consumption, ATP and ability to grow in soft agar and as poorly differentiated tumors in athymic mice. PMID: 22917272
    5. Data show that Bcl-2 expression positively influences the targeting of nuclear-encoded COX Va and Vb to the mitochondria of cancer cells. PMID: 19834492

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
  • 蛋白家族:
    Cytochrome c oxidase subunit 5B family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 2269

    OMIM: 123866

    KEGG: hsa:1329

    STRING: 9606.ENSP00000258424

    UniGene: Hs.1342



主站蜘蛛池模板: 久久综合九色综合97网| 亚洲精品无码永久中文字幕| 好疼太大了太粗太长了视频| 欧美真人性做爰一二区| 无码aⅴ精品一区二区三区浪潮| 台湾佬中文娱乐22vvvv| 亚洲国产成人av网站| 亚洲成av人片在线观看橙子| 欧美精品亚洲精品日韩专区一乛方| 无码成a毛片免费| 亚洲中文字幕无码一久久区 | 国产中文欧美日韩在线| 久久精品第一国产久精国产宅男66 | 鲁鲁狠狠狠7777一区二区 | 久久久一本精品99久久精品88 | 乱子伦av无码中文字| 中文字幕资源网| 国产成人精品一区二区三区| 国产69精品久久久久999小说| 狠狠做深爱婷婷久久综合一区| 亚洲人禽杂交av片久久| 亚洲aⅴ天堂av天堂无码| 国产真实乱人偷精品人妻| 国产麻豆精品久久一二三| 日本少妇内射视频播放舔| 露脸叫床粗话东北少妇| 波多野结衣av无码| 国产亚洲视频在线播放香蕉| 在线看片免费人成视频国产片| 日本丰满熟妇hd| 国产精品无码久久久久久久久久| 国精品人妻无码一区二区三区d3| 亚洲精品久久yy5099| 精品 在线 视频 亚洲| 人妻色综合网站| 99久久er这里只有精品18| 天堂亚洲国产中文在线| 扒开双腿疯狂进出爽爽爽视频| 人妻教师痴汉电车波多野结衣 | 狠狠色色综合站| 99久久人妻无码精品系列蜜桃|