在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

COL9A1 Antibody

  • 中文名稱:
    COL9A1兔多克隆抗體
  • 貨號:
    CSB-PA005757ESR1HU
  • 規(guī)格:
    ¥440
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) COL9A1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    COL9A1Collagen alpha-1(IX) chain antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Collagen alpha-1(IX) chain protein (20-270AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Structural component of hyaline cartilage and vitreous of the eye.
  • 基因功能參考文獻(xiàn):
    1. the COL9A1 rs35470562 variant may contribute to congenital talipes equinovarus susceptibility in the Chinese population examined. PMID: 27819742
    2. We observed a significant association between rs6910140 of COL9A1 and KBD, suggesting a role of COL9A1 in the development of KBD. PMID: 25774918
    3. The study demonstrated that hypermethylation is associated with down-regulation of COL9A1 expression in osteoarthritic (OA) cartilage and highlights the pivotal role of epigenetics in OA. PMID: 25048791
    4. The NC2 domain of type IX collagen determines the chain composition but also the chain register of the triple helix. PMID: 23132862
    5. Type IX collagen interacts with fibronectin providing an important molecular bridge in articular cartilage PMID: 21768108
    6. A second, novel mutation was identified in COL9A1, causing autosomal recessive Stickler syndrome together with the previously described nucleotide change in two separate families. PMID: 21421862
    7. COL9A1 protein is highly expressed in patients with idiopathic congenital talipes equinovarus (ICTEV) and rs1135056, which is located in the coding region of COL9A1 gene, may be associated with the pathogenesis of ICTEV. PMID: 21672422
    8. NC2 domain of collagen IX provides chain selection and heterotrimerization PMID: 20507993
    9. This study extends the range of gene-mutations that can cause multiple epiphyseal dysplasia-related myopathy. PMID: 20358595
    10. Data show that the proximal-promoter region of the human COL9A1 gene can drive expression of a reporter gene in chondrocytic RCS cells, but not in nonchondrocytic cell lines. PMID: 12399468
    11. the amino-terminal NC4 domain of human collagen IX interacts with glycosaminoglycans and cartilage oligomeric matrix protein PMID: 15047691
    12. COMP, type IX collagen and MATN3 play important roles in matrix assembly PMID: 15694129
    13. A search of the microRNA database revealed a highly conserved target sequence for miR-9 immediately preceding the overlapping polyadenylation signals in the novel 3' UTR of COL9A1, suggesting its role in posttranscriptional regulation of COL9A1. PMID: 16718610
    14. COL9A1 is the fourth identified gene that can cause Stickler syndrome. PMID: 16909383
    15. analysis of the crystal structure of the N-terminal NC4 domain of collagen IX PMID: 17553797
    16. the matrilin-3 A-domain appears to bind exclusively to the COL3 domain of type IX collagen and this binding is abolished in the presence of a disease causing mutation in type IX collagen PMID: 17881354
    17. mutation causes multiple epiphyseal dysplasia; genetic heterogeneity PMID: 11565064

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Multiple epiphyseal dysplasia 6 (EDM6); Stickler syndrome 4 (STL4)
  • 亞細(xì)胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Fibril-associated collagens with interrupted helices (FACIT) family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 2217

    OMIM: 120210

    KEGG: hsa:1297

    STRING: 9606.ENSP00000349790

    UniGene: Hs.590892



主站蜘蛛池模板: 亚洲午夜免费福利视频| ass日本丰满熟妇pics| 日韩综合夜夜香内射| 国产日产欧洲无码视频| 欧美尺码专线欧洲b1b1| 亚洲成a∧人片在线观看无码| 在线天堂资源www在线污| 男女啪啦啦超猛烈动态图| 中文字幕一区二区三区乱码| 秋霞午夜成人久久电影网| 天堂中文8资源在线8| 欧美成aⅴ人高清怡红院 | 精品人妻少妇嫩草av无码专区| a毛看片免费观看视频| 亚洲日韩a∨无码久| 免费很黄无遮挡的视频| 在办公室被c到呻吟的动态图| 久久国产精品-国产精品| 国产精品国产自线拍免费不卡| 国产女人天天春夜夜春| 午夜伦费影视在线观看| 成人国产亚洲精品a区天堂| 成片免费观看视频大全| 久久精品成人免费国产片小草| 色婷婷五月综合色啪网| 亚洲国产欧洲综合997久久| 日韩乱码人妻无码中文字幕久久| 国产高清在线精品一区小说| 国产99视频精品免视看7| 亚洲欧洲日产国码无码久久99| 色综合久久久无码中文字幕| 蜜桃日本免费观看mv| 国产黄在线观看免费观看软件| 麻豆精品一区二区综合av| 中文乱码人妻系列一区二区| 国产超碰女人任你爽| 在线 v亚洲 v欧美v 专区| 午夜无码一区二区三区在线观看| 亚洲日韩看片无码电影| 日本动漫瀑乳h动漫啪啪免费| 日韩国产成人无码av毛片|