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COG5 Antibody

  • 中文名稱：
    COG5兔多克隆抗體
  • 貨號：
    CSB-PA890771ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: COG5 antibody at 2.04 μg/ml
      Lane 1: Mouse large intestine tissue
      Lane 2: A549 whole cell lysate
      Lane 3: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 93, 95, 91 kDa
      Observed band size: 93, 70 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA890771ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA890771ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) COG5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    COG5
  • 別名：
    COG5 antibody; GOLTC1 antibody; GTC90Conserved oligomeric Golgi complex subunit 5 antibody; COG complex subunit 5 antibody; 13S Golgi transport complex 90 kDa subunit antibody; GTC-90 antibody; Component of oligomeric Golgi complex 5 antibody; Golgi transport complex 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Conserved oligomeric Golgi complex subunit 5 protein (1-260AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Required for normal Golgi function.
  • 基因功能參考文獻(xiàn)：
    1. Targeted silencing of components of lobe B of the COG complex, namely COG5, COG6, COG7 and COG8, inhibited HIV-1 replication PMID: 25179963
    2. Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex. PMID: 25331899
    3. In conclusion, we find that GDF5, but not COG5 or MCF2L, influence the extent of radiographic damage in knee osteoarthritis PMID: 22615457
    4. Report on a uterine leiomyoma with a novel HMGA2 fusion gene in a 44-year-old woman. PMID: 20804914
    5. Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp PMID: 11929878
    6. COG5- and COG7 subunits play distinctive roles in controlling Golgi structure and function PMID: 16051600

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  • 相關(guān)疾病：
    Congenital disorder of glycosylation 2I (CDG2I)
  • 亞細(xì)胞定位：
    Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein.
  • 蛋白家族：
    COG5 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 14857

    OMIM: 606821

    KEGG: hsa:10466

    STRING: 9606.ENSP00000297135

    UniGene: Hs.239631



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