在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CGGBP1 Antibody

  • 中文名稱:
    CGGBP1兔多克隆抗體
  • 貨號:
    CSB-PA070082
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CGGBP1
  • 別名:
    20 kDa CGG binding protein antibody; 20 kDa CGG-binding protein antibody; CGBP1_HUMAN antibody; CGG binding protein 1 antibody; CGG triplet repeat binding protein 1 antibody; CGG triplet repeat-binding protein 1 antibody; CGG-binding protein 1 antibody; CGGBP 1 antibody; CGGBP antibody; Cggbp1 antibody; OTTHUMP00000213853 antibody; OTTHUMP00000213877 antibody; p20 CGG binding protein antibody; p20 CGGBP antibody; p20 CGGBP DNA binding protein antibody; p20-CGGBP DNA-binding protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human CGGBP1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter.
  • 基因功能參考文獻:
    1. By studying global gene expression patterns and genome-wide DNA-binding patterns of CGGBP1, it has been shown that a possible mechanism through which it affects the expression of RNA Pol II-transcribed genes in trans depends on Alu RNA. PMID: 25483050
    2. CGGBP1 has no direct effect on FMR1 transcription and CGG repeat stability. PMID: 26306647
    3. CGGBP1 protein play an important cytoprotective role in patients with cancer. PMID: 26482656
    4. CGGBP1 is a possible bidirectional regulator of CpG methylation at Alus, and acts as a repressor of methylation at L1 retrotransposons. PMID: 25981527
    5. Our results suggest that CGGBP1 phosphorylation at S164 is a novel telomere protection signal, which can affect telomere-protective function of the shelterin complex PMID: 24196442
    6. Over-expression of miR-7 could significantly inhibit the growth of human lung cancer cells in vivo and in vitro, which might be related to the down-regulated expression of tumor growth-associated protein CGGBP1 PMID: 24491049
    7. CGGBP1 depletion by RNA interference in tumor-derived cells caused an increase in the cell population at G0/G1 phase and reduced the number of cells in the S phase. PMID: 21733196
    8. CGGBP-20 downregulates the activity of 5'-region of FMR1 gene in the presence of GCC-triplets only. PMID: 20141036
    9. CGGBP1 was mapped to chromosome 3p and a sequence of 235 nucleotides 5' upstream of CGGBP1 is essential for promoter activity. PMID: 14667814
    10. Differences in factors implicated in CGG repeat instability--CGG repeat size, XS548/FRAXAC1 haplotypes, and AGG interspersion pattern-are present in the Basque populations analyzed. PMID: 19728537

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Ubiquitous. Highly expressed in placenta, thymus, lymph nodes, cerebellum and cerebral cortex. Low expression in other regions of the brain.
  • 數據庫鏈接:

    HGNC: 1888

    OMIM: 603363

    KEGG: hsa:8545

    STRING: 9606.ENSP00000381428

    UniGene: Hs.444818



主站蜘蛛池模板: 性xxxxx大片免费视频| 亚洲色成人中文字幕网站| 人妻体内射精一区二区| 老湿机69福利区18禁网站| av无码久久久精品免费| 青青草原精品资源站久久| 99国内精品久久久久久久| 欧洲美熟女乱又伦av影片| 国产亚洲精品久久久久久入口| 18禁成人黄网站免费观看久久| 久久婷婷人人澡人人爽人人爱| 伊人久久综合成人网| 亚洲444kkkk在线观看| 朋友的丰满人妻中文字幕| 国产无遮挡裸体免费视频在线观看| 亚洲精品一区国产| 国产日韩亚洲大尺度高清| 激情按摩系列片aaaa| 狠狠色噜噜狠狠狠8888米奇| 久久久综合九色合综国产精品| 亚洲欧洲精品无码av| 久久午夜神器| 爱性久久久久久久久| 国产精品麻豆成人av网| 2019午夜福利不卡片在线| 国产精品十八禁在线观看| 做爰高潮视频免费的看| 久久久精品人妻一区二区三区gv | 婷婷网亚洲色偷偷男人的天堂| 中国熟女仑乱hd| 丰满女人又爽又紧又丰满| 亚洲欧美日本国产专区一区| 精品国产一区二区三区av色诱| 成人丝袜激情一区二区| 精品国产一区二区三区四区五区| 久久人人妻人人爽人人爽| 在线成人爽a毛片免费软件| 少妇饥渴xxhd麻豆xxhd骆驼| 看国产黄大片在线观看| 老熟女老太婆爽| 日韩网红少妇无码视频香港 |