在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CFD Antibody

  • 中文名稱(chēng):
    CFD兔多克隆抗體
  • 貨號(hào):
    CSB-PA005271ESR2HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA005271ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA005271ESR2HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng):
    Rabbit anti-Homo sapiens (Human) CFD Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Adipsin antibody; Adipsin/complement factor D antibody; Adn antibody; C3 convertase activator antibody; CFAD_HUMAN antibody; CFD antibody; Complement factor D antibody; complement factor D preproprotein antibody; D component of complement antibody; DF antibody; FactorD antibody; PFD antibody; Properdin factor D antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Complement factor D protein (26-253AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類(lèi)型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
  • 基因功能參考文獻(xiàn):
    1. MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked. PMID: 27535802
    2. disturbance of reciprocal relationships between adipsin and leptin in obesity is associated with the development of insulin resistance PMID: 28864895
    3. TZDs (pioglitazone, rosiglitazone, and ciglitazone) slow tumor cell growth in vitro and in vivo with decreases in cell proliferation and increases in PPARg and adipsin PMID: 28219679
    4. The strong association of PLIN1, CFD and ADIPOQ genes with adipogenesis prompted authors to study the influence the bone health status as evaluated by quantitative ultrasound (QUS) bone densitometer in a North Indian cohort. Overall, ADIPOQ (rs1501299 and rs3774261) and combined cluster of PLIN1 rs2304796 and rs2304795) and CFD (rs1683563) demonstrated correlation. PMID: 28189761
    5. our findings set up a novel mechanism for FABP4, adipsin and adiponectin through gut microbiota mediating expression in gut Paneth cells. PMID: 26687459
    6. Overall adipsin levels among male asbestos industry workers were significantly higher than among control subjects. PMID: 25840635
    7. Data indicate that a urinary protein, adipsin, was significantly increased in patients with preeclampsia. PMID: 24958499
    8. Study demonstrates that T2DM patients with beta cell failure are deficient in adipsin. PMID: 24995977
    9. Complement factor D (FD) is activated by its substrate through interactions outside the active site which lock the unbound native state into an ordered inactive conformation via the self-inhibitory loop in FD. PMID: 24598742
    10. We demonstrate novel secretion of adipsin and ASP by placental Hofbauer cells. PMID: 23956345
    11. Increased activation of the alternative complement pathway in vitreous was controlled by disease stage and genetic variation in the complement pathway, supporting a role for complement activation in macular degeneration disease pathogenesis. PMID: 22930722
    12. Anti factor D Fab fragment inhibits FD proteolytic function by interfering with macromolecular substrate access rather than by inhibiting FD catalysis. PMID: 22362762
    13. CFD regulates activation of the alternative complement pathway, which is implicated in age related macular degeneration pathogenesis. PMID: 22003108
    14. CFD may not play a major role in the genetic susceptibility to age-related macular degeneration. PMID: 21139680
    15. crystal structure of C3bB at 4 A and complex with factor D at 3.5 A; data show how factor B binding to C3b forms open "activation" state of C3bB; Factor D binds open conformation of factor B through a site distant from the catalytic center PMID: 21205667
    16. As adiponectin and adipsin levels in CSF did not correlate with their levels in plasma, it seems that there could be a secondary intrathecal synthesis of these adipocytokines in multiple sclerosis PMID: 19538214
    17. increased serum levels in patients with seasonal allergic rhinitis PMID: 19699327

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Complement factor D deficiency (CFDD)
  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    Peptidase S1 family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 2771

    OMIM: 134350

    KEGG: hsa:1675

    STRING: 9606.ENSP00000332139

    UniGene: Hs.155597



主站蜘蛛池模板: 天天躁日日躁狠狠躁av| 蜜桃少妇av久久久久久久| 久久人人97超碰a片精品| 艳妇乳肉豪妇荡乳在线观看| 内射人妻少妇无码一本一道| 99草草国产熟女视频在线| 少妇高潮太爽了在线观看| 天天综合网亚在线| 亚洲精品v日韩精品| 久久久无码一区二区三区| 亚洲精品国产av天美传媒| 玩弄少妇的肉体k8经典| 亚洲精品无码精品mv在线观看 | 久久久久成人精品免费播放动漫| 少妇又爽又刺激视频| 女性自慰网站免费观看w| 国产成人无码短视频| 欧美肥胖老妇bbw| 国产又色又爽又黄的在线观看视频| 性无码专区一色吊丝中文字幕| 亚洲娇小与黑人巨大交| 99精品无人区乱码在线观看| 亚洲综合激情另类小说区| 亚洲va在线va天堂va欧美va| 48沈阳熟女高潮嗷嗷叫| 一边添奶一边添p好爽视频| 成年午夜性影院免费观看| 亚洲第一天堂无码专区| 久久亚洲精品无码va白人极品| 欧美人做人爱a全程免费| 欧美成人精品三级一二三在线观看| 无套内射chinesehd熟女| 欧美交换国产一区内射| 东京热一区二区三区无码视频| 亚洲高清成人aⅴ片| 老子影院午夜伦不卡无码| 无套内射极品少妇chinese| 夜夜爽狠狠天天婷婷五月| 亚洲欧洲精品无码av| 日本亚洲欧洲无免费码在线| 日本人妻人人人澡人人爽|