在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CELSR1 Antibody

  • 中文名稱:
    CELSR1兔多克隆抗體
  • 貨號:
    CSB-PA982432
  • 規格:
    ¥2024
  • 圖片:
    • Immunofluorescence analysis of MCF-7 cells, using CELSR1 antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CELSR1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from internal of Human CELSR1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:100-1:500
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor that may have an important role in cell/cell signaling during nervous system formation.
  • 基因功能參考文獻:
    1. Patients with CELSR1 mutations and spina bifida can have significant renal malformations. PMID: 27597235
    2. This single-nucleotide polymorphism-by-sex genome-wide association analysis identified the fetal lung development gene, CELSR1, as a potential sex-specific risk factor for Chronic obstructive pulmonary disease. PMID: 27854507
    3. Upregulating CELSR1 expression significantly promoted cell growth, while knocking down CELSR1 inhibited the growth and decreased tube formation. PMID: 27301287
    4. Single nucleotide polymorphisms in nNOS, renalase, MTHFR, CELSR1 and XYLB genes were found significantly associated with ischemic stroke in Chinese patients. PMID: 25855559
    5. the present study has proven for the first time that CELSR1 is a susceptibility gene for ischaemic stroke in the Chinese Han population, especially for large artery atherosclerosis. PMID: 25117632
    6. CELSR1 mutations contribute to the risk of spina bifida in a cohort of spina bifida patients from California PMID: 24632739
    7. Celsr1 regulates dynamic cell movements by inhibiting stabilization of VE-cadherin and maturation of adherens junctions. PMID: 23792146
    8. CELSR1 is a risk factor for neural tube defects or caudal agenesis via pathogenic role of planar cell polarity signaling in these malformations. PMID: 22371354
    9. Missense variants in CELSR1 may represent a cause of craniorachischisis in humans, as in mice, with defective planar cell polarity protein trafficking to the plasma membrane a likely pathogenic mechanism. PMID: 22095531
    10. CELSR1 may have a role in ischemic stroke, as shown in a Portuguese case-control cohort PMID: 21511255
    11. The planar cell polarity genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis. PMID: 20223754
    12. Identification of CELSR1 as a susceptibility gene for ischemic stroke in Japanese individuals by a genome-wide association study. PMID: 19403135
    13. exclusion as a candidate gene for schizophrenia-- a cadhrin gene PMID: 11807409
    14. Variations in the nine ectodomains of CELSR1 do not increase susceptibility to schizophrenia. PMID: 12782967

    顯示更多

    收起更多

  • 相關疾病:
    Neural tube defects (NTD)
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 2 family, LN-TM7 subfamily
  • 數據庫鏈接:

    HGNC: 1850

    OMIM: 182940

    KEGG: hsa:9620

    STRING: 9606.ENSP00000262738

    UniGene: Hs.252387



主站蜘蛛池模板: 亚洲国产成人极品综合| 亚洲愉拍99热成人精品| 国产内射老熟女aaaa∵| 亚洲人成自拍网站在线观看| 欧美亚洲日本日韩在线| 久久久久99精品成人片试看 | 亚洲欧美日韩国产自偷| 男人j桶进女人p无遮挡免费观看| 国产97在线 | 免费| 日韩精品无码一区二区三区视频| 国产成人夜色高潮福利影视| 亚洲日韩国产精品第一页一区| 97精品一区二区视频在线观看| 国产99在线 | 免费| 99久久99视频只有精品| 国产精品区免费视频| 国产69精品久久久久777| 国产在线一区二区在线视频 | 国语自产拍精品香蕉在线播放| 永久免费观看美女裸体视频的网站| 伊人成色综合网| 性色欲情网站iwww| 欧美性xxxx极品hd欧美风情| 日韩欧美亚洲综合久久影院| 日韩成人无码一区二区三区| 亚洲婷婷六月的婷婷| 蜜桃视频在线观看免费网址入口| 天美麻花果冻视频大全英文版| 处破痛哭a√18成年片免费| 黄网站色视频免费观看| 大又大又粗又硬又爽少妇毛片| 国产亚洲一区二区在线观看| 欧美亚洲国产精品久久| 国产啪视频1000部免费| av免费网址在线观看 | 日本人又黄又爽又色的视频| 日韩不卡1卡2卡三卡2021精品推荐| 国产精品成人99一区无码 | 国产精品久线在线观看| 国产精品白浆在线观看免费| 精品亚洲国产成人av制服|