在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CELSR1 Antibody, HRP conjugated

  • 中文名稱:
    CELSR1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA868360NB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CELSR1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    CELSR1 antibody; CDHF9 antibody; FMI2Cadherin EGF LAG seven-pass G-type receptor 1 antibody; Cadherin family member 9 antibody; Flamingo homolog 2 antibody; hFmi2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence from Human Cadherin EGF LAG seven-pass G-type receptor 1 protein (345-363AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor that may have an important role in cell/cell signaling during nervous system formation.
  • 基因功能參考文獻:
    1. Patients with CELSR1 mutations and spina bifida can have significant renal malformations. PMID: 27597235
    2. This single-nucleotide polymorphism-by-sex genome-wide association analysis identified the fetal lung development gene, CELSR1, as a potential sex-specific risk factor for Chronic obstructive pulmonary disease. PMID: 27854507
    3. Upregulating CELSR1 expression significantly promoted cell growth, while knocking down CELSR1 inhibited the growth and decreased tube formation. PMID: 27301287
    4. Single nucleotide polymorphisms in nNOS, renalase, MTHFR, CELSR1 and XYLB genes were found significantly associated with ischemic stroke in Chinese patients. PMID: 25855559
    5. the present study has proven for the first time that CELSR1 is a susceptibility gene for ischaemic stroke in the Chinese Han population, especially for large artery atherosclerosis. PMID: 25117632
    6. CELSR1 mutations contribute to the risk of spina bifida in a cohort of spina bifida patients from California PMID: 24632739
    7. Celsr1 regulates dynamic cell movements by inhibiting stabilization of VE-cadherin and maturation of adherens junctions. PMID: 23792146
    8. CELSR1 is a risk factor for neural tube defects or caudal agenesis via pathogenic role of planar cell polarity signaling in these malformations. PMID: 22371354
    9. Missense variants in CELSR1 may represent a cause of craniorachischisis in humans, as in mice, with defective planar cell polarity protein trafficking to the plasma membrane a likely pathogenic mechanism. PMID: 22095531
    10. CELSR1 may have a role in ischemic stroke, as shown in a Portuguese case-control cohort PMID: 21511255
    11. The planar cell polarity genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis. PMID: 20223754
    12. Identification of CELSR1 as a susceptibility gene for ischemic stroke in Japanese individuals by a genome-wide association study. PMID: 19403135
    13. exclusion as a candidate gene for schizophrenia-- a cadhrin gene PMID: 11807409
    14. Variations in the nine ectodomains of CELSR1 do not increase susceptibility to schizophrenia. PMID: 12782967

    顯示更多

    收起更多

  • 相關疾病:
    Neural tube defects (NTD)
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 2 family, LN-TM7 subfamily
  • 數據庫鏈接:

    HGNC: 1850

    OMIM: 182940

    KEGG: hsa:9620

    STRING: 9606.ENSP00000262738

    UniGene: Hs.252387



主站蜘蛛池模板: 国产一区二区三区久久精品| 东京热无码国产精品| 色视频www在线播放国产人成| 国产精品夜夜春夜夜爽久久小说| 国产熟人av一二三区| 无码熟妇人妻av在线影片 | 国产免费人成视频尤勿视频| 欧美婷婷六月丁香综合| 久久97超碰色中文字幕总站| 高潮毛片无遮挡高清免费| 欧美人与禽猛交狂配| 午夜爱爱免费视频体验区| 午夜福利av无码一区二区| 99亚洲男女激情在线观看| 亚洲乱亚洲乱妇中文影视| 欧洲极品无码一区二区三区| 国产欧美丝袜在线二区| 午夜天堂一区人妻| 女人被狂躁c到高潮| av高清无码 在线播放| 亚洲国产丝袜精品一区| 窝窝午夜理论片影院| 人妻无码中文字幕免费视频蜜桃| 亚洲欧美人成网站在线观看看| 一本热久久sm色国产| 人妻少妇精品中文字幕av| 国产精品亚洲精品日韩己满十八小 | 午夜福利视频极品国产83| 无码少妇一区二区浪潮av| 深夜福利视频在线播放| 精产国品一二三产区蘑菇视频| 亚洲人成电影免费观看在线看| 国产欧美va天堂在线观看视频| 久久久久亚洲精品男人的天堂| 奇米777四色在线精品| 天堂在线.www天堂在线资源| 久久精品国产99国产精品澳门| 欧洲免费无线码在线一区| 精品国产中文字幕在线视频| 欲香欲色天天综合和网| 久久国产色av免费看|