在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CDKN2AIP Antibody

CDKN2AIP Antibody

  • 中文名稱：
    CDKN2AIP兔多克隆抗體
  • 貨號(hào)：
    CSB-PA696531
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA696531(CDKN2AIP Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CDKN2AIP
  • 別名：
    Calcium response factor antibody; CARF antibody; CARF_HUMAN antibody; CDKN2A interacting protein antibody; CDKN2A-interacting protein antibody; Cdkn2aip antibody; collaborates/cooperates with ARF (alternate reading frame) protein antibody; Collaborator of ARF antibody; FLJ20036 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Fusion protein of Human CDKN2AIP
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Regulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence.
  • 基因功能參考文獻(xiàn)：
    1. a comprehensive current understanding into the molecular mechanisms of CARF functions in regulation of DNA damage response, cell cycle checkpoints, cell survival and death signaling pathways. PMID: 28754531
    2. report that CARF (Collaborator of ARF) is a new target of miR-335 that regulates its growth suppressor function by complex crosstalk with other proteins including p16(INK4A), pRB, HDM2 and p21(WAF1) PMID: 27457128
    3. Oncogenic functions of CARF in hepatocellular carcinoma tumorigenesis is a result of activation of beta-catenin/TCF signaling. PMID: 27829235
    4. CARF promotes carcinogenesis in p53-deficient cells by repressing p21WAF1 and promoting cell cycle progression. PMID: 26278998
    5. The results suggest that CARF regulates early steps of pre-rRNA processing during ribosome biogenesis by controlling spatial distribution of XRN2 between the nucleoplasm and nucleolus. PMID: 26531822
    6. CARF regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signaling. PMID: 24825908
    7. Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66, USP20 and OR7C2 in a Korean population. PMID: 22552337
    8. CARF knockdown elicited DNA damage response as evidenced by increased levels of phosphorylated ATM and gammaH2AX, leading to induction of mitotic arrest and eventual apoptosis. PMID: 21052095
    9. CARF may act as a novel key regulator of the p53 pathway at multiple checkpoints PMID: 18555516
    10. cooperates with human p14ARF in activating p53 PMID: 12154087
    11. CARF may exert a vital control on p53-HDM2-p21(WAF1) pathway that is central to the cell cycle control, senescence, and DNA damage response of human cells PMID: 17460193
    12. CARF exerts a vital control on the p53-HDM2-p21WAF1 pathway that is frequently altered in cancer cells. PMID: 18292944
    13. CARF plays a dual role in regulating p53-mediated senescence and apoptosis, the two major tumor suppressor mechanisms. PMID: 19001376

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus, nucleoplasm.
  • 蛋白家族：
    CARF family
  • 組織特異性：
    Ubiquitously expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24325

    OMIM: 615914

    KEGG: hsa:55602

    STRING: 9606.ENSP00000427108

    UniGene: Hs.592508



主站蜘蛛池模板： 久久久精品456亚洲影院| 无码帝国www无码专区色综合| 在线资源天堂www| 任我爽橹在线精品视频| 国产精品99久久久久久董美香| 后入到高潮免费观看| 777久久精品一区二区三区无码| 日本十八禁视频无遮挡| 无码尹人久久相蕉无码| 国产美女精品自在线拍免费 | 国产裸体xxxx视频在线播放| 大战丰满无码人妻50p| 浪潮av激情高潮国产精品| 日韩av影院在线观看| 色综合色综合久久综合频道88| 84pao国产成视频永久免费| 国产av无码专区亚洲草草| 亚洲中文字幕a∨在线| 国产又a又黄又潮娇喘视频| 欧美三根一起进三p| 亚洲熟妇无码一区二区三区导航| 女人喷水高潮时的视频网站| 免费能直接看黄的视频| 成人亚洲欧美激情在线电影| 真实的国产乱xxxx| 18禁裸男晨勃露j毛免费观看| 成在人线av无码免费看| 国产高清-国产av| 免费国产污网站在线观看| 亚洲 丝袜 另类 校园 欧美| 国产激情久久久久久熟女老人av| 久久www香蕉免费人成| 丰满少妇大叫太大太粗| 好想被狂躁无码视频在线观看| 一本大道熟女人妻中文字幕在线| 天天躁日日躁狠狠很躁| 国产真实野战在线视频| 久久精品av一区二区免费| 无码h肉动漫在线观看| 久久欧美国产伦子伦精品| 夜夜精品无码一区二区三区|