在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CDKN2AIP Antibody

CDKN2AIP Antibody

  • 中文名稱：
    CDKN2AIP兔多克隆抗體
  • 貨號：
    CSB-PA687184
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA687184(CDKN2AIP Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    CDKN2AIP
  • 別名：
    Calcium response factor antibody; CARF antibody; CARF_HUMAN antibody; CDKN2A interacting protein antibody; CDKN2A-interacting protein antibody; Cdkn2aip antibody; collaborates/cooperates with ARF (alternate reading frame) protein antibody; Collaborator of ARF antibody; FLJ20036 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Fusion protein of Human CDKN2AIP
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence.
  • 基因功能參考文獻：
    1. a comprehensive current understanding into the molecular mechanisms of CARF functions in regulation of DNA damage response, cell cycle checkpoints, cell survival and death signaling pathways. PMID: 28754531
    2. report that CARF (Collaborator of ARF) is a new target of miR-335 that regulates its growth suppressor function by complex crosstalk with other proteins including p16(INK4A), pRB, HDM2 and p21(WAF1) PMID: 27457128
    3. Oncogenic functions of CARF in hepatocellular carcinoma tumorigenesis is a result of activation of beta-catenin/TCF signaling. PMID: 27829235
    4. CARF promotes carcinogenesis in p53-deficient cells by repressing p21WAF1 and promoting cell cycle progression. PMID: 26278998
    5. The results suggest that CARF regulates early steps of pre-rRNA processing during ribosome biogenesis by controlling spatial distribution of XRN2 between the nucleoplasm and nucleolus. PMID: 26531822
    6. CARF regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signaling. PMID: 24825908
    7. Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66, USP20 and OR7C2 in a Korean population. PMID: 22552337
    8. CARF knockdown elicited DNA damage response as evidenced by increased levels of phosphorylated ATM and gammaH2AX, leading to induction of mitotic arrest and eventual apoptosis. PMID: 21052095
    9. CARF may act as a novel key regulator of the p53 pathway at multiple checkpoints PMID: 18555516
    10. cooperates with human p14ARF in activating p53 PMID: 12154087
    11. CARF may exert a vital control on p53-HDM2-p21(WAF1) pathway that is central to the cell cycle control, senescence, and DNA damage response of human cells PMID: 17460193
    12. CARF exerts a vital control on the p53-HDM2-p21WAF1 pathway that is frequently altered in cancer cells. PMID: 18292944
    13. CARF plays a dual role in regulating p53-mediated senescence and apoptosis, the two major tumor suppressor mechanisms. PMID: 19001376

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus, nucleoplasm.
  • 蛋白家族：
    CARF family
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：

    HGNC: 24325

    OMIM: 615914

    KEGG: hsa:55602

    STRING: 9606.ENSP00000427108

    UniGene: Hs.592508



主站蜘蛛池模板： 亚洲成a人片在线观看日本| 日韩精品人妻无码久久影院| 国产露脸精品产三级国产av| 蜜臀av片在线观看| 无码办公室丝袜ol中文字幕| 日产一区日产2区| 丝袜自慰一区二区三区| 亚洲国产精品久久久久4婷婷| 农村乱人伦一区二区| 亚洲成av人片香蕉片| 亚洲国产一区二区波多野结衣| 好日子在线观看视频大全免费动漫 | 老色鬼永久视频网站| 中老年熟妇激情啪啪大屁股| 精品国产三级a∨在线欧美| 999国内精品永久免费视频| 丰满少妇高潮惨叫久久久一| 人妻有码av中文字幕久久琪| 忘忧草日本在线www| 国产亚洲欧美日韩在线观看一区| 青青草原精品99久久精品66| 婷婷四房综合激情五月| 亚洲人成人伊人成综合网无码| 欧美亚洲日本国产其他| 亚洲精品无码专区| 少妇性l交大片7724com | 国产妇女馒头高清泬20p多| 精品久久久无码中文字幕边打电话| 亚洲色大网站www永久网站| 中文天堂最新版资源www官网| 国产精品丝袜黑色高跟鞋| av无码小缝喷白浆在线观看| 免费观看国产小粉嫩喷水| 1000部拍拍拍18勿入免费视频| 无码国产精品一区二区免费式芒果| 麻豆蜜桃av蜜臀av色欲av| 国产产在线精品亚洲aavv| 亚洲电影在线观看| 色先锋资源久久综合5566| 第一亚洲中文久久精品无码| 日韩精品一区二区三区视频|