在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CCRL2 Antibody

  • 中文名稱:
    CCRL2兔多克隆抗體
  • 貨號:
    CSB-PA001416
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HepG2 cells using CCRL2 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    CCRL2; CCR11; CCR6; CKRX; CRAM; HCR; C-C chemokine receptor-like 2; Chemokine receptor CCR11; Chemokine receptor X; Putative MCP-1 chemokine receptor
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human CCRL2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses.
  • 基因功能參考文獻:
    1. CCRL2 mRNA was not significantly changed in murine and human non-alcoholic steatohepatitis liver. CCRL2 mRNA levels were positively correlated with inflammation, fibrosis and NASH scores in the patients. PMID: 28600126
    2. CCRL2 inhibited the growth of breast cancer cells in vitro and in vivo. PMID: 26487662
    3. in breast cancer, CRAM-A becomes specifically upregulated under inflammatory stimuli and may serve as a potential marker of immune response. PMID: 26563945
    4. these results suggest for the first time that elevated CCRL2 in glioma promotes cell migration and invasion. PMID: 23142225
    5. Considering the newly defined role of CCRL2 in lung dendritic cell trafficking, this atypical chemokine receptor may affect pneumocystis pneumonia through immune regulation and inducing inflammation. PMID: 22046140
    6. demonstration that the homeostatic chemokine CCL19 is a specific ligand for CRAM PMID: 20002784
    7. CCRL2 expression is up-regulated on synovial neutrophils of rheumatoid arthritis patients PMID: 15188357
    8. Results identify chemerin as a natural nonsignaling protein ligand for both human and mouse CCRL2. PMID: 18794339

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Expressed abundantly in immunal tissues such as spleen, fetal liver, lymph node and bone marrow. Strong expression also in lung and heart. Expressed in almost all hematopoietic cells including monocytes, macrophages, PMNs, T-cells (both CD4+ and CD8+), mo
  • 數據庫鏈接:

    HGNC: 1612

    OMIM: 608379

    KEGG: hsa:9034

    STRING: 9606.ENSP00000349967

    UniGene: Hs.535713



主站蜘蛛池模板: 国产精品久久久久野外| 免费网站观看www在线观看| 亚洲国产精品久久精品| 人妻夜夜爽天天爽| 永久免费毛片在线播放| 69国产成人精品午夜福中文| 亚洲人成无码网站| 在线观看欧美一区二区三区| 久久婷婷五月综合色d啪| 亚洲精品美女久久777777| 亚洲国产av一区二区三区| 人人妻人人澡人人爽国产一区 | 欧美日韩一卡2卡三卡4卡 乱码欧美孕交| 高潮潮喷奶水飞溅视频无码| 欧美做爰性生交视频| 人妻妺妺窝人体色www聚色窝| 黑人巨大videos精品| 中文字幕制服丝袜人妻动态图| 情人伊人久久综合亚洲| 东方aⅴ免费观看久久av| 狠狠做久久深爱婷婷| 毛片无码免费无码播放| 全球av集中精品导航福利| 韩国无码av片在线观看| 婷婷成人五月综合激情| 久久久久国产精品嫩草影院 | 亚洲第一在线综合网站| 中文字幕久热精品视频在线| 亚洲天堂男人影院| 人人澡人摸人人添| 国产在线观看无码不卡| 国产又大又硬又粗| 欧美两根一起进3p做受视频| 久久久久中文伊人久久久| 国产午夜精品av一区二区麻豆| 国产精品人妻| 国产毛片不卡野外视频| 小13箩利洗澡无码视频网站| 日韩av无码中文字幕| 亚洲中文字幕久久精品无码va| 国产精品免费久久久久软件|