在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CCNG1 Antibody

  • 中文名稱:
    CCNG1兔多克隆抗體
  • 貨號:
    CSB-PA004820GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    CCNG 1 antibody; CCNG antibody; CCNG1 antibody; CCNG1_HUMAN antibody; CYCG1 antibody; Cyclin G antibody; Cyclin G1 antibody; Cyclin-G antibody; Cyclin-G1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CCNG1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
  • 基因功能參考文獻:
    1. miR-516b functions as a tumor suppressor by directly modulating CCNG1 expression in esophageal squamous carcinoma cells. PMID: 30119241
    2. Low CCNG1 expression is associated with cancer. PMID: 29787434
    3. Data show that the miR-27b/cyclin G1 protein (CCNG1)/p53 tumor suppressor protein (P53)/miR-508-5p axis plays important roles in gastric cancer (GC)-associated multidrug resistance (MDR). PMID: 26623719
    4. Results show that miR-23b may inhibit epithelial ovarian tumorigenesis and progression by targeting CCNG1 and modulating the expression of the relevant genes. PMID: 26872615
    5. OA induced cell cycle arrest in lung cancer cells through miR-122/Cyclin G1/MEF2D pathway. This finding may contribute to the understanding of the molecular mechanism of OA's anti-tumor activity PMID: 25472877
    6. Progesterone-induced cyclin G1 mediates the inhibitory effect of progesterone on endometrial epithelial cell proliferation. PMID: 25007270
    7. cyclin G1 exerts negative control on proliferation of endometrial carcinoma cells (ECCs). PMID: 23589924
    8. cyclin G1 levels were increased in normal tissue compared with hepatocellular carcinoma tissue and vary over the course of the cell cycle, with equal distribution between the nucleus and cytoplasm. PMID: 22835824
    9. data suggest that the deficiency of progesterone and its receptors is an important cause of the decreased expression of cyclin G1 in endometrial carcinoma, which may account for carcinogenesis and development of endometrial carcinomas PMID: 22649121
    10. Cyclin G1 overexpression enhanced Akt activation through interaction with p85 (regulatory subunit of phosphoinositide 3-kinase) PMID: 22271581
    11. Expression of cyclin G1 and G2 is strongly associated with nasopharyngeal carcinoma cell differentiation. PMID: 21688120
    12. Loss of microRNA 122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G(1) -modulated P53 activity. PMID: 22105316
    13. Low expression of P27(kip1) and the high expression of cyclin G in patients acute leukemia may have some correlation with genesis and development of the disease. PMID: 19698214
    14. cyclin G1 has growth inhibitory activity that is mechanistically linked to ARF-p53 and pRb tumor suppressor pathways. PMID: 12556559
    15. does not increase significantly during colorectal carcinogenesis and during later metastasis to lymph nodes. PMID: 12684677
    16. cyclin G has a role in ATM-dependent p53 regulation and in cell cycle regulation during DNA damage PMID: 15077171
    17. cyclin G1 is a target of miR-122a in human hepatocellular carcinoma PMID: 17616664
    18. the cyclin box has a role in the proteasome-mediated degradation of cyclin G1 PMID: 18632610
    19. The B'alpha1 subunit of the serine/threonine protein phosphatase 2A, which binds to cyclin G1, can stabilize cyclin G1 under unstressed conditions and upon DNA damage, as well as inhibit the ability of cyclin G1 to be ubiquitinated. PMID: 18981217
    20. Results show that in patients resected for HCC, lower miR-122 levels were associated with a shorter TTR, whereas higher cyclin G1 expression was related to a lower survival, suggesting that miR-122 might represent an effective molecular target for HCC. PMID: 19584283

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Note=DNA replication foci after DNA damage.
  • 蛋白家族:
    Cyclin family, Cyclin G subfamily
  • 組織特異性:
    High levels in skeletal muscle, ovary, kidney and colon.
  • 數據庫鏈接:

    HGNC: 1592

    OMIM: 601578

    KEGG: hsa:900

    STRING: 9606.ENSP00000344635

    UniGene: Hs.79101



主站蜘蛛池模板: av大片在线无码免费| 国产喷水1区2区3区咪咪爱av| 欧美亚洲日本国产综合在线| 尤物蜜芽国产成人精品区| 国产精品美女久久久久av爽| 无码精品人妻一区二区三区98| 早起邻居人妻奶罩太松av | 亚洲国产日韩制服在线观看| 丝袜 亚洲 另类 欧美 变态| 国产网红主播无码精品| 成人无码男男gv在线观看网站| 337p粉嫩日本欧洲亚福利| av无码中出一区二区三区| 亚洲精品成a人在线观看| 女人裸体性做爰视频| 夜夜躁狠狠躁日日躁202| 国内久久婷婷六月综合欲色啪 | 久久丫精品久久丫| 国产精品无码素人福利| 亚洲欧美另类成人综合图片| 在线永久无码不卡av| a国产一区二区免费入口| 天堂在线中文网www| 国产精品午夜爆乳美女视频| 中文字幕aⅴ在线视频| 18禁黄无遮挡网站| 成人午夜无码专区性视频性视频| 亚洲欧美成人一区二区在线| 亚洲熟女乱色一区二区三区| 女人被狂躁60分钟视频 | 99久久精品精品6精品精品| 欧美特级婬片毛多的少妇| 香蕉久久人人爽人人爽人人片av| 国产乱子伦精品视频| 日本看片一二三区高清| 国产熟妇乱子伦视频在线观看| 夜夜高潮夜夜爽国产伦精品 | 国产亚洲精品久久yy5099| 男女做爰猛烈啪啪吃奶伸舌头下载| 欧美野性肉体狂欢大派对| 国产9色在线 | 日韩|