在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CCNG1 Antibody

  • 中文名稱:
    CCNG1兔多克隆抗體
  • 貨號(hào):
    CSB-PA203465
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from Jurkat cells, using Cyclin G antibody.
    • Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Cyclin G antibody.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) CCNG1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from Human Cyclin G.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
  • 基因功能參考文獻(xiàn):
    1. miR-516b functions as a tumor suppressor by directly modulating CCNG1 expression in esophageal squamous carcinoma cells. PMID: 30119241
    2. Low CCNG1 expression is associated with cancer. PMID: 29787434
    3. Data show that the miR-27b/cyclin G1 protein (CCNG1)/p53 tumor suppressor protein (P53)/miR-508-5p axis plays important roles in gastric cancer (GC)-associated multidrug resistance (MDR). PMID: 26623719
    4. Results show that miR-23b may inhibit epithelial ovarian tumorigenesis and progression by targeting CCNG1 and modulating the expression of the relevant genes. PMID: 26872615
    5. OA induced cell cycle arrest in lung cancer cells through miR-122/Cyclin G1/MEF2D pathway. This finding may contribute to the understanding of the molecular mechanism of OA's anti-tumor activity PMID: 25472877
    6. Progesterone-induced cyclin G1 mediates the inhibitory effect of progesterone on endometrial epithelial cell proliferation. PMID: 25007270
    7. cyclin G1 exerts negative control on proliferation of endometrial carcinoma cells (ECCs). PMID: 23589924
    8. cyclin G1 levels were increased in normal tissue compared with hepatocellular carcinoma tissue and vary over the course of the cell cycle, with equal distribution between the nucleus and cytoplasm. PMID: 22835824
    9. data suggest that the deficiency of progesterone and its receptors is an important cause of the decreased expression of cyclin G1 in endometrial carcinoma, which may account for carcinogenesis and development of endometrial carcinomas PMID: 22649121
    10. Cyclin G1 overexpression enhanced Akt activation through interaction with p85 (regulatory subunit of phosphoinositide 3-kinase) PMID: 22271581
    11. Expression of cyclin G1 and G2 is strongly associated with nasopharyngeal carcinoma cell differentiation. PMID: 21688120
    12. Loss of microRNA 122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G(1) -modulated P53 activity. PMID: 22105316
    13. Low expression of P27(kip1) and the high expression of cyclin G in patients acute leukemia may have some correlation with genesis and development of the disease. PMID: 19698214
    14. cyclin G1 has growth inhibitory activity that is mechanistically linked to ARF-p53 and pRb tumor suppressor pathways. PMID: 12556559
    15. does not increase significantly during colorectal carcinogenesis and during later metastasis to lymph nodes. PMID: 12684677
    16. cyclin G has a role in ATM-dependent p53 regulation and in cell cycle regulation during DNA damage PMID: 15077171
    17. cyclin G1 is a target of miR-122a in human hepatocellular carcinoma PMID: 17616664
    18. the cyclin box has a role in the proteasome-mediated degradation of cyclin G1 PMID: 18632610
    19. The B'alpha1 subunit of the serine/threonine protein phosphatase 2A, which binds to cyclin G1, can stabilize cyclin G1 under unstressed conditions and upon DNA damage, as well as inhibit the ability of cyclin G1 to be ubiquitinated. PMID: 18981217
    20. Results show that in patients resected for HCC, lower miR-122 levels were associated with a shorter TTR, whereas higher cyclin G1 expression was related to a lower survival, suggesting that miR-122 might represent an effective molecular target for HCC. PMID: 19584283

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus. Note=DNA replication foci after DNA damage.
  • 蛋白家族:
    Cyclin family, Cyclin G subfamily
  • 組織特異性:
    High levels in skeletal muscle, ovary, kidney and colon.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 1592

    OMIM: 601578

    KEGG: hsa:900

    STRING: 9606.ENSP00000344635

    UniGene: Hs.79101



主站蜘蛛池模板: 免费视频爱爱太爽了激情| 四虎影视永久免费观看| av色欲无码人妻中文字幕| 国内精品视频自在一区| 国产卡一卡二卡三卡免费| 欧美18videosex性欧美黑吊| 超碰97人人射妻| 国内精品久久久久影院嫩草| 狠狠做久久深爱婷婷| 中国精学生妹品射精久久| 中文字幕色av一区二区三区 | 我把护士日出水了视频90分钟| 国产无遮挡又黄又爽免费网站| 亚洲中文字幕av无码区| 欧美丰满熟妇xxxx性ppx人| 久久综合久色欧美综合狠狠| 人禽杂交18禁网站免费| 免费的av网站在线观看国产精品| 欧美 日韩 亚洲 精品二区| 国产精品51麻豆cm传媒| 中文字幕无码毛片免费看| 国产精品亚洲专区无码老司国 | 中文字幕精品亚洲无线码一区| 好大好湿好硬顶到了好爽视频| 亚洲成本人无码薄码区| 中文字幕无码家庭乱欲| 又大又粗又长的高潮视频| 久久久久久久久无码精品亚洲日韩 | 农民人伦一区二区三区| 国产精品亚洲一区二区三区喷水| 欧美性xxxx极品hd欧美风情| 免费无码肉片在线观看| 中文在线а√天堂| 人妻人人澡人人添人人爽人人玩| 五月天天天综合精品无码| 日韩 欧美 动漫 国产 制服| 国产人妻高清国产拍精品| 亚洲一线二线三线品牌精华液久久久| 色www视频永久免费| 亚洲欧洲无卡二区视頻| 亚洲综合网站精品一区二区|