在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CBLN1 Antibody

  • 中文名稱(chēng):
    CBLN1兔多克隆抗體
  • 貨號(hào):
    CSB-PA945254
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from HUVEC cells, using CBLN1 antibody.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng):
    Rabbit anti-Homo sapiens (Human) CBLN1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human CBLN1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類(lèi)型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Required for synapse integrity and synaptic plasticity. During cerebellar synapse formation, essential for the matching and maintenance of pre- and post-synaptic elements at parallel fiber-Purkinje cell synapses, the establishment of the proper pattern of climbing fiber-Purkinje cell innervation, and induction of long-term depression at parallel fiber-Purkinje cell synapses. Plays a role as a synaptic organizer that acts bidirectionally on both pre- and post-synaptic components. On the one hand induces accumulation of synaptic vesicles in the pre-synaptic part by binding with NRXN1 and in other hand induces clustering of GRID2 and its associated proteins at the post-synaptic site through association of GRID2. NRXN1-CBLN1-GRID2 complex directly induces parallel fiber protrusions that encapsulate spines of Purkinje cells leading to accumulation of GRID2 and synaptic vesicles. Required for CBLN3 export from the endoplasmic reticulum and secretion. NRXN1-CBLN1-GRID2 complex mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis. Essential for long-term maintenance but not establishment of excitatory synapses. Inhibits the formation and function of inhibitory GABAergic synapses in cerebellar Purkinje cells.; The cerebellin peptide exerts neuromodulatory functions. Directly stimulates norepinephrine release via the adenylate cyclase/PKA-dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release.
  • 基因功能參考文獻(xiàn):
    1. Cbln1 and Cbln2 are co-expressed in the endolysosomal compartment of the thalamic neurons responsible for the synaptic alterations in striatum of Cbln1-null mice. PMID: 22117778
  • 亞細(xì)胞定位:
    Secreted. Cell junction, synapse, postsynaptic cell membrane.
  • 組織特異性:
    In the Purkinje cells postsynaptic structures. In the cerebellum, cerebellin is much less abundant than [des-Ser1]-cerebellin.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 1543

    OMIM: 600432

    KEGG: hsa:869

    STRING: 9606.ENSP00000219197

    UniGene: Hs.458423



主站蜘蛛池模板: 国产国产久热这里只有精品| 92电影网午夜福利| 亚洲日韩国产一区二区三区| 国产传媒麻豆剧精品av国产 | 国产美女遭强高潮网站下载| 东京热人妻丝袜av无码| 久久精品国产精品亚洲毛片| 免费人妻精品一区二区三区| s级爆乳玩具酱国产vip皮裤| 国产亚洲精品一区在线播放| 日日摸日日碰夜夜爽av| 美女露全乳无遮掩视频| 午夜天堂一区人妻| 国产欧美精品aaaaaa片| 丰满护士巨好爽好大乳| 亚洲精品国产一二三无码av| 影音先锋中文字幕人妻| 国产精品你懂的在线播放| 宅男宅女精品国产av天堂| 久久九九精品国产免费看小说| 极品美女扒开粉嫩小泬| 亚洲熟妇久久精品| 国产av老师丝袜美腿丝袜| 久久天天躁狠狠躁夜夜2019| 亚洲爆乳无码精品aaa片蜜桃| 5x性社区免费视频播| 久久精品国产只有精品2020| 新版天堂资源中文8在线| 波多野结衣av无码| 午夜福利视频极品国产83| 无遮挡很爽很污很黄的网站| 午夜片无码区私人影院| 永久免费无码成人网站| 伊人色综合九久久天天蜜桃| 中文成人无字幕乱码精品区| 天天做天天躁天天躁| 亚洲成αv人片在线观看| 欧美真人性做爰全过程| 人人妻人人澡人人爽欧美一区 | 久久综合a∨色老头免费观看| 熟妇人妻无乱码中文字幕|